1-(4-Methoxyphenyl)piperazine hydrochloride
Based on 1 Customer Validation
1-(4-Methoxyphenyl)piperazine (Piperazine, 1- (4-methoxyphenyl)-) hydrochloride is a piperazine derivative with neural activity.
For research use only. We do not sell to patients.
- Purity : 99.27%
- CAS No.: 38869-47-5
- Formula: C11H18Cl2N2O
- Molecular Weight:265.18
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Storage:
Store at room temperature, keep dry and cool.
In solvent -80°C, 1 year , -20°C, 6 months
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Cyclo(Phe-Asp)Aspartame Impurity
Biological Activity
Description
Chemical Information
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CAS No. 38869-47-5
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Appearance Solid
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Molecular Weight 265.18
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Formula C11H18Cl2N2O
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Color Off-white to light brown
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SMILES
COC1=CC=C(N2CCNCC2)C=C1.Cl.Cl
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Synonyms
Piperazine, 1- (4-methoxyphenyl)-, dihydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature, keep dry and cool
In solvent -80°C 1 year -20°C 6 months
Solvent & Solubility
In Vitro:
DMSO : 25 mg/mL (94.28 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (9.43 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 3.7710 mL | 18.8551 mL | 37.7102 mL | 94.2756 mL |
| 5 mM | 0.7542 mL | 3.7710 mL | 7.5420 mL | 18.8551 mL | |
| 10 mM | 0.3771 mL | 1.8855 mL | 3.7710 mL | 9.4276 mL | |
| 15 mM | 0.2514 mL | 1.2570 mL | 2.5140 mL | 6.2850 mL | |
| 20 mM | 0.1886 mL | 0.9428 mL | 1.8855 mL | 4.7138 mL | |
| 25 mM | 0.1508 mL | 0.7542 mL | 1.5084 mL | 3.7710 mL | |
| 30 mM | 0.1257 mL | 0.6285 mL | 1.2570 mL | 3.1425 mL | |
| 40 mM | 0.0943 mL | 0.4714 mL | 0.9428 mL | 2.3569 mL | |
| 50 mM | 0.0754 mL | 0.3771 mL | 0.7542 mL | 1.8855 mL | |
| 60 mM | 0.0629 mL | 0.3143 mL | 0.6285 mL | 1.5713 mL | |
| 80 mM | 0.0471 mL | 0.2357 mL | 0.4714 mL | 1.1784 mL |
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