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Cat. No.: HY-A0198A

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Adinazolam mesylate

(Synonyms: U 41123F mesylate)

Adinazolam (U 41123F) mesylate is a triazolobenzodiazepine. Adinazolam mesylate binds to peripheral-type benzodiazepine receptors which interact allosterically with GABA receptors. Adinazolam mesylate has dual anxiolytic and antidepressant activities.

For research use only. We do not sell to patients.

CAS No.: 57938-82-6
Formula: C₂₀H₂₂ClN₅O₃S
Molecular Weight:447.94

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Adinazolam mesylate Chemical Structure

CAS No.: 57938-82-6

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vivo

Adinazolam (6 mg/kg) mesylate increases shuttlebox avoidance acquisition in male Sprague-Dawley rats^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Male Sprague-Dawley rats weighing 409±30 g^[2]
Dosage:

6 mg/kg
Administration:

Administered i.p. in 2 mL/kg
Result:

Increased avoidance acquisition in 195% as compared to control animals.

Chemical Information

CAS No. 57938-82-6
Molecular Weight 447.94
Formula C₂₀H₂₂ClN₅O₃S
SMILES

O=S(O)(C)=O.ClC1=CC(C(C2=CC=CC=C2)=NCC3=NN=C(CN(C)C)N43)=C4C=C1
Synonyms

U 41123F mesylate
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. P A Broderick.Adinazolam affects biogenic amine release in hippocampal CA1 neuronal circuitry.Brain Res Bull. 1991 Nov;27(5):689-92. [Content Brief]

[2]. R M Escorihuela,et al. Flumazenil prevents the anxiolytic effects of diazepam, alprazolam and adinazolam on the early acquisition of two-way active avoidance. Pharmacol Res. Jul-Aug 1993;28(1):53-8. [Content Brief]

[3]. Adinazolam.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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