Adinazolam
Based on 1 Customer Validation
Adinazolam (U 41123) is a triazolobenzodiazepine. Adinazolam binds to peripheral-type benzodiazepine receptors which interact allosterically with GABA receptors. Adinazolam has dual anxiolytic and antidepressant activities.
For research use only. We do not sell to patients.
- Purity: 99.0%
- CAS No.: 37115-32-5
- Formula: C19H18ClN5
- Molecular Weight:351.83
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Sprague-Dawley rats weighing 409±30 g[2]
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Dosage:6 mg/kg
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Administration:Administered i.p. in 2 mL/kg
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Result:Increased avoidance acquisition in 195% as compared to control animals.
Chemical Information
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CAS No. 37115-32-5
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Appearance Solid
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Molecular Weight 351.83
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Formula C19H18ClN5
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Color White to off-white
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SMILES
CN(C)CC1=NN=C2N1C3=CC=C(Cl)C=C3C(C4=CC=CC=C4)=NC2
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Synonyms
U 41123
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : 1 mg/mL (2.84 mM; Need ultrasonic and warming)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (570 KB)
- English - EN (570 KB)
- Français - FR (570 KB)
- Deutsch - DE (570 KB)
- Norwegian - NO (570 KB)
- Español - ES (570 KB)
- Swedish - SV (570 KB)
- Italian - IT (570 KB)
- Korean - KR (570 KB)
- Portuguese - PT (570 KB)
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Handling Instructions (2659 KB)
References
[1]. P A Broderick.Adinazolam affects biogenic amine release in hippocampal CA1 neuronal circuitry.Brain Res Bull. 1991 Nov;27(5):689-92. [Content Brief]
[2]. R M Escorihuela,et al. Flumazenil prevents the anxiolytic effects of diazepam, alprazolam and adinazolam on the early acquisition of two-way active avoidance. Pharmacol Res. Jul-Aug 1993;28(1):53-8. [Content Brief]
[3]. Adinazolam.
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 2.8423 mL | 14.2114 mL | 28.4228 mL | 71.0570 mL |
Adinazolam Related Classifications
HY-A0198 Related Classifications
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