Adinazolam-d5
Adinazolam-d5 (U 41123-d5) is a deuterium labeled Adinazolam (HY-A0198). Adinazolam is a triazolobenzodiazepine. Adinazolam binds to peripheral-type benzodiazepine receptors which interact allosterically with GABA receptors. Adinazolam has dual anxiolytic and antidepressant activities.
For research use only. We do not sell to patients.
- Formula: C19H13D5ClN5
- Molecular Weight:356.86
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 37115-32-5
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Molecular Weight 356.86
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Formula C19H13D5ClN5
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SMILES
CN(C)CC1=NN=C2N1C3=CC=C(Cl)C=C3C(C4=C([2H])C([2H])=C([2H])C([2H])=C4[2H])=NC2
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Synonyms
U 41123-d5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. P A Broderick.Adinazolam affects biogenic amine release in hippocampal CA1 neuronal circuitry.Brain Res Bull. 1991 Nov;27(5):689-92. [Content Brief]
[2]. R M Escorihuela,et al. Flumazenil prevents the anxiolytic effects of diazepam, alprazolam and adinazolam on the early acquisition of two-way active avoidance. Pharmacol Res. Jul-Aug 1993;28(1):53-8. [Content Brief]
[3]. Adinazolam.
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)