37115-32-5
37115-32-5
Chemical Structure
Adinazolam
Synonym(s): U 41123
- CAS No.: 37115-32-5
- Formula:C19H18ClN5
- Molecular Weight:351.83
IUPAC Name: 1-(8-chloro-6-phenyl-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepin-1-yl)-N,N-dimethylmethanamine
InChIKey: GJSLOMWRLALDCT-UHFFFAOYSA-N
SMILES: CN(C)CC1=NN=C2N1C3=CC=C(Cl)C=C3C(C4=CC=CC=C4)=NC2
Biological Activity: Adinazolam (U 41123) is a triazolobenzodiazepine. Adinazolam binds to peripheral-type benzodiazepine receptors which interact allosterically with GABA receptors. Adinazolam has dual anxiolytic and antidepressant activities[1][2][3].
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Adinazolam | 99.0% | Adinazolam (U 41123) is a triazolobenzodiazepine. Adinazolam binds to peripheral-type benzodiazepine receptors which interact allosterically with GABA receptors. Adinazolam has dual anxiolytic and antidepressant activities. | ||||||||||||||||||||
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Adinazolam-d5 | Adinazolam-d5 (U 41123-d5) is a deuterium labeled Adinazolam (HY-A0198). Adinazolam is a triazolobenzodiazepine. Adinazolam binds to peripheral-type benzodiazepine receptors which interact allosterically with GABA receptors. Adinazolam has dual anxiolytic and antidepressant activities. | |||||||||||||||||||||
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References
- [1]. P A Broderick.Adinazolam affects biogenic amine release in hippocampal CA1 neuronal circuitry.Brain Res Bull. 1991 Nov;27(5):689-92. [Content Brief]
- [2]. R M Escorihuela,et al. Flumazenil prevents the anxiolytic effects of diazepam, alprazolam and adinazolam on the early acquisition of two-way active avoidance. Pharmacol Res. Jul-Aug 1993;28(1):53-8. [Content Brief]
- [3]. Adinazolam.
