PROTAC SMARCA2/4 degrader-39
PROTAC SMARCA2/4 degrader-39 (Compound 7) is a selective degrader of SMARCA2 (BRM) and SMARCA4 (BRG1) PROTAC. PROTAC SMARCA2/4 degrader-39 is promising for research of oncology, such as non-small cell lung cancer and colorectal cancer.
(Pink: SMARCA2 and SMARCA4 Target protein ligand; Blue: Cereblon ligand (HY-168055); Black: linker).
For research use only. We do not sell to patients.
- CAS No.: 3099581-74-2
- Formula: C41H43N9O6
- Molecular Weight:757.84
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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SMARCA2 |
SMARCA4 |
Chemical Information
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CAS No. 3099581-74-2
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Molecular Weight 757.84
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Formula C41H43N9O6
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SMILES
CC[C@@](N1C2)(CNC3=C1C=C(C4=C(O)C=CC=C4)N=N3)C[C@H]2OC(N=C5)=C(C)C=C5C(N(CC6)CCN6C7=CC(C8=O)=C(C=C7)CN8[C@H](C(N9)=O)CCC9=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)