Thalidomide-5-piperazine-azetidine TFA
Thalidomide-5-piperazine-azetidine (TFA) is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
For research use only. We do not sell to patients.
- CAS No.: 3065021-28-2
- Formula: C22H24F3N5O6
- Molecular Weight:511.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Biological Activity
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Chemical Information
- Purity & Documentation
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Help & FAQs
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
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Cereblon |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3065021-28-2
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Molecular Weight 511.45
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Formula C22H24F3N5O6
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SMILES
O=C1NC(C(CC1)N2C(C3=CC=C(N4CCN(C5CNC5)CC4)C=C3C2=O)=O)=O.O=C(C(F)(F)F)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Thalidomide-5-piperazine-azetidine TFA Related Classifications
HY-W998322 Related Classifications
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