3065021-28-2
3065021-28-2
Chemical Structure
Thalidomide-5-piperazine-azetidine TFA
- CAS No.: 3065021-28-2
- Formula:C22H24F3N5O6
- Molecular Weight:511.45
IUPAC Name: 5-(4-(azetidin-3-yl)piperazin-1-yl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione 2,2,2-trifluoroacetate
InChIKey: DZAVGJWAJAUXHT-UHFFFAOYSA-N
SMILES: O=C1NC(C(CC1)N2C(C3=CC=C(N4CCN(C5CNC5)CC4)C=C3C2=O)=O)=O.O=C(C(F)(F)F)O
Biological Activity: Thalidomide-5-piperazine-azetidine (TFA) is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
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Thalidomide-5-piperazine-azetidine TFA | Thalidomide-5-piperazine-azetidine (TFA) is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC. | |||||||||||||||||||||
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