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Cat. No.: HY-169377

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Lenalidomide-C13-piperazine-Boc

Lenalidomide-C13-piperazine-Boc is a conjugate of the E3 ligase ligand and the linker, that can be used for synthesis of PROTAC degrader NC-R17 (HY-155075).

For research use only. We do not sell to patients.

CAS No.: 3043895-40-2
Formula: C₃₅H₅₅N₅O₅
Molecular Weight:625.84

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (262 KB)

Lenalidomide-C13-piperazine-Boc Chemical Structure

CAS No.: 3043895-40-2

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Lenalidomide-C13-piperazine-Boc is a conjugate of the E3 ligase ligand and the linker, that can be used for synthesis of PROTAC degrader NC-R17 (HY-155075)^[1].

All E3 Ligase Ligand-Linker Conjugates Isoforms :

Chemical Information

CAS No. 3043895-40-2
Molecular Weight 625.84
Formula C₃₅H₅₅N₅O₅
SMILES

O=C(N1CCN(CCCCCCCCCCCCCNC2=CC=CC3=C2CN(C4C(NC(CC4)=O)=O)C3=O)CC1)OC(C)(C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (262 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zheng C, et al. Structure-activity relationship study of RSL3-based GPX4 degraders and its potential noncovalent optimization. Eur J Med Chem. 2023 Jul 5;255:115393. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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Chemical Information
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References

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Lenalidomide-C13-piperazine-Boc

All E3 Ligase Ligand-Linker Conjugates Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Lenalidomide-C13-piperazine-Boc Related Classifications

HY-169377 Related Classifications