1-(3-Fluorophenyl)piperazine hydrochloride

Name: 1-(3-Fluorophenyl)piperazine hydrochloride
Brand: MedChemExpress
SKU: HY-W073336A
Rating: 4.5 (1 reviews)

Cat. No.: HY-W073336A Purity: 98.03%: Data Sheet
COA

SDS
Handling Instructions
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1-(3-Fluorophenyl)piperazine hydrochloride is a 5-HT receptor 1A blocker and an adrenergic receptor blocker.

For research use only. We do not sell to patients.

1-(3-Fluorophenyl)piperazine hydrochloride Chemical Structure

CAS No. : 76835-10-4

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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α adrenergic receptor β adrenergic receptor

View All 5-HT Receptor Isoform Specific Products:

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5-HT Receptor 5-HT₁ Receptor 5-HT₂ Receptor 5-HT₃ Receptor 5-HT₄ Receptor 5-HT₅ Receptor 5-HT₆ Receptor 5-HT₇ Receptor

Biological Activity
Purity & Documentation
References
Customer Review

Description

1-(3-Fluorophenyl)piperazine hydrochloride is a 5-HT receptor 1A blocker and an adrenergic receptor blocker.

Molecular Weight

253.14

Formula

C₁₀H₁₅Cl₂FN₂

CAS No.

76835-10-4

Appearance

Solid

Color

Yellow to orange

SMILES

FC1=CC=CC(N2CCNCC2)=C1.Cl.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : ≥ 100 mg/mL (395.04 mM)

DMSO : 50 mg/mL (197.52 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.9504 mL	19.7519 mL	39.5038 mL
5 mM	0.7901 mL	3.9504 mL	7.9008 mL
10 mM	0.3950 mL	1.9752 mL	3.9504 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 98.03%

Select Batch:

Data Sheet (269 KB) SDS (252 KB)

COA (248 KB) HNMR (160 KB) LCMS (106 KB)

Handling Instructions (2659 KB)

References

[1]. Martin GE, Elgin RJ Jr, Mathiasen JR, et al. Activity of aromatic substituted phenylpiperazines lacking affinity for dopamine binding sites in a preclinical test of antipsychotic efficacy. J Med Chem. 1989;32(5):1052-1056. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / H₂O	1 mM	3.9504 mL	19.7519 mL	39.5038 mL	98.7596 mL
	5 mM	0.7901 mL	3.9504 mL	7.9008 mL	19.7519 mL
	10 mM	0.3950 mL	1.9752 mL	3.9504 mL	9.8760 mL
	15 mM	0.2634 mL	1.3168 mL	2.6336 mL	6.5840 mL
	20 mM	0.1975 mL	0.9876 mL	1.9752 mL	4.9380 mL
	25 mM	0.1580 mL	0.7901 mL	1.5802 mL	3.9504 mL
	30 mM	0.1317 mL	0.6584 mL	1.3168 mL	3.2920 mL
	40 mM	0.0988 mL	0.4938 mL	0.9876 mL	2.4690 mL
	50 mM	0.0790 mL	0.3950 mL	0.7901 mL	1.9752 mL
	60 mM	0.0658 mL	0.3292 mL	0.6584 mL	1.6460 mL
	80 mM	0.0494 mL	0.2469 mL	0.4938 mL	1.2345 mL
	100 mM	0.0395 mL	0.1975 mL	0.3950 mL	0.9876 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.