2. PROTAC
  3. E3 Ligase Ligand-Linker Conjugates
  4. 2-(2,6-Dioxopiperidin-3-yl)phthalimidine-piperazine-C-piperidine hydrochloride

2-(2,6-Dioxopiperidin-3-yl)phthalimidine-piperazine-C-piperidine hydrochloride 

Cat. No.: HY-W1115219
Handling Instructions Technical Support

2-(2,6-Dioxopiperidin-3-yl)phthalimidine-piperazine-C-piperidine hydrochloride is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.

For research use only. We do not sell to patients.

2-(2,6-Dioxopiperidin-3-yl)phthalimidine-piperazine-C-piperidine hydrochloride

2-(2,6-Dioxopiperidin-3-yl)phthalimidine-piperazine-C-piperidine hydrochloride Chemical Structure

CAS No. : 2806001-88-5

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2-(2,6-Dioxopiperidin-3-yl)phthalimidine-piperazine-C-piperidine hydrochloride Related Antibodies

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Description

2-(2,6-Dioxopiperidin-3-yl)phthalimidine-piperazine-C-piperidine hydrochloride is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.

IC50 & Target

Cereblon

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

2-(2,6-Dioxopiperidin-3-yl)phthalimidine-piperazine-C-piperidine hydrochloride Related Antibodies
Formula

C23H32ClN5O3
CAS No.
SMILES

O=C1NC(C(CC1)N2C(C3=CC=C(N4CCN(CC5CCNCC5)CC4)C=C3C2)=O)=O.Cl.[x]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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2-(2,6-Dioxopiperidin-3-yl)phthalimidine-piperazine-C-piperidine hydrochloride Related Classifications

  • Molarity Calculator

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2-(2,6-Dioxopiperidin-3-yl)phthalimidine-piperazine-C-piperidine2806001-88-5E3 Ligase Ligand-Linker ConjugatesInhibitorinhibitorinhibit

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2-(2,6-Dioxopiperidin-3-yl)phthalimidine-piperazine-C-piperidine hydrochloride
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