VGSCs-IN-1
Based on 1 Customer Validation
VGSCs-IN-1 (compound 14), a 2-piperazine analog of Riluzole (HY-B0211), is a human voltage-gated sodium channels (VGSCs) inhibitor. VGSCs-IN-1 shows great Nav1.4 blocking activity. VGSCs-IN-1 has a pKa of 7.6 and a cLog P of 2.4. VGSCs-IN-1 can be used for cell excitability disorders research.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 99.92%
- CAS No.: 1204296-79-6
- 화학식: C12H12F3N3OS
- 분자량:303.30
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
IC50 & Target
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hNav1.4 |
hNav1.7 |
Chemical Information
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CAS No. 1204296-79-6
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Appearance Solid
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분자량 303.30
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화학식 C12H12F3N3OS
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Color White to off-white
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SMILES
FC(F)(F)OC1=CC2=C(C=C1)N=C(N3CCNCC3)S2
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
In Vitro:
DMSO : 50 mg/mL (164.85 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.2971 mL | 16.4853 mL | 32.9707 mL | 82.4266 mL |
| 5 mM | 0.6594 mL | 3.2971 mL | 6.5941 mL | 16.4853 mL | |
| 10 mM | 0.3297 mL | 1.6485 mL | 3.2971 mL | 8.2427 mL | |
| 15 mM | 0.2198 mL | 1.0990 mL | 2.1980 mL | 5.4951 mL | |
| 20 mM | 0.1649 mL | 0.8243 mL | 1.6485 mL | 4.1213 mL | |
| 25 mM | 0.1319 mL | 0.6594 mL | 1.3188 mL | 3.2971 mL | |
| 30 mM | 0.1099 mL | 0.5495 mL | 1.0990 mL | 2.7476 mL | |
| 40 mM | 0.0824 mL | 0.4121 mL | 0.8243 mL | 2.0607 mL | |
| 50 mM | 0.0659 mL | 0.3297 mL | 0.6594 mL | 1.6485 mL | |
| 60 mM | 0.0550 mL | 0.2748 mL | 0.5495 mL | 1.3738 mL | |
| 80 mM | 0.0412 mL | 0.2061 mL | 0.4121 mL | 1.0303 mL | |
| 100 mM | 0.0330 mL | 0.1649 mL | 0.3297 mL | 0.8243 mL |
VGSCs-IN-1 Related Classifications
HY-W031620 Related Classifications
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