ALK5 ligand-1-amine-C2-piperazine-C4-OH
ALK5 ligand-1-amine-C2-piperazine-C4-OH is a conjugate of a ligand targeting ALK5 and a PROTAC linker. ALK5 ligand-1-amine-C2-piperazine-C4-OH can be used to synthesize the PROTAC degrader (a31). ALK5 PROTACs induce UPS-dependent and selective degradation of ALK5 over ALK4. ALK5 ligand-1-amine-C2-piperazine-C4-OH can be applied to research on pulmonary fibrosis.
For research use only. We do not sell to patients.
- Formula: C30H35ClFN7O3
- Molecular Weight:596.10
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Chemical Information
-
Molecular Weight 596.10
-
Formula C30H35ClFN7O3
-
SMILES
ClC1=CC(C2=CC(N3C4=CC=NC=C4N(CC(NCCN5CCN(CCCCO)CC5)=O)C3=O)=C(C)C=N2)=C(F)C=C1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)