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11s-31r-16-36-37-trimethoxy-12-32-dimethyl-11-12-13-14-31-32-33-34-oc

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Payload (1) Amino Acid Derivatives (1) Apoptosis (5) Autophagy (4) Bacterial (1) Biochemical Assay Reagents (22) Dipeptidyl Peptidase (1) Drug Derivative (10) Drug Intermediate (11) Drug Isomer (1) Drug Metabolite (1) Endogenous Metabolite (12) Environmental Pollutants (6) Fungal (2) Glycosidase (1) HIV (3) Isocitrate Dehydrogenase (IDH) (1) Isotope-Labeled Compounds (7) Keap1-Nrf2 (3) Microtubule/Tubulin (1) Mitochondrial Metabolism (1) Mitosis (1) MOFs (7) Nucleoside Antimetabolite/Analog (1) Opioid Receptor (1) Phosphatase (1) Potassium Channel (1) Prolyl Endopeptidase (PREP) (1) Prostaglandin Receptor (1) PROTAC Linkers (1) Proteasome (1) Reactive Oxygen Species (ROS) (6) Reference Standards (11) Wnt (1)
By Research Areas:	Cancer (9) Cardiovascular Disease (2) Endocrinology (2) Infection (8) Inflammation/Immunology (7) Metabolic Disease (22) Neurological Disease (13)
Oligonucleotides:	Solvents (1)

100

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-44134

Dimethyl 2-oxoglutarate 1 Publications Verification dimethyl α-ketoglutarate	Endogenous Metabolite Drug Derivative Autophagy Mitochondrial Metabolism Reactive Oxygen Species (ROS)	Cardiovascular Disease Neurological Disease Metabolic Disease
Dimethyl 2-oxoglutarate (Dimethyl α-ketoglutarate) is a cell-permeable derivative of 2-oxoglutarate and tricarboxylic acid cycle metabolite with antioxidant properties. Dimethyl 2-oxoglutarate inhibits Autophagy. Dimethyl 2-oxoglutarate prevents mitochondrial damage and reduces ROS production. Dimethyl 2-oxoglutarate alleviates Carbon tetrachloride (HY-Y0298)-induced liver fibrosis. Dimethyl-2-oxoglutaric acid can be used in the research of diseases such as Alzheimer's disease, diabetes, and cardiomyopathy .

HY-17363

Dimethyl fumarate Maximum Cited Publications 56 Publications Verification	Keap1-Nrf2 Reactive Oxygen Species (ROS) HIV Autophagy Endogenous Metabolite	Infection Neurological Disease Inflammation/Immunology Cancer
Dimethyl fumarate (DMF) is an orally active and brain-penetrant Nrf2 activator and induces upregulation of antioxidant gene expression. Dimethyl fumarate induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway, and also induces cell autophagy. Dimethyl fumarate can be used for multiple sclerosis research .

HY-Y1787

Dimethyl malonate 5+ Cited Publications	Apoptosis	Neurological Disease
Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase (SDH). Dimethyl malonate is able to cross the blood-brain barrier and hydrolyse to malonate. Dimethyl malonate reduces neuronal apoptosis .

HY-Y0808

Dimethyl succinate 1 Publications Verification	Environmental Pollutants Apoptosis	Neurological Disease Metabolic Disease
Dimethyl succinate is an orally active cell permeable succinate analogue. Dimethyl succinate can disrupt the TCA cycle by elevating intracellular succinate levels, leading to reduced protein synthesis and impairs myogenic differentiation. Dimethyl succinate can induce apoptosis. Dimethyl succinate can decrease maximal cellular respiration and reserve capacity. Dimethyl succinate can rescue synapse loss in AD. Dimethyl succinate can be used for the researches of metabolic and neurological disease ^[1][2].

HY-106420

*16,16-Dimethyl* prostaglandin E2** 16,16-dimethyl PGE2	Wnt Prostaglandin Receptor	Inflammation/Immunology
16,16-Dimethyl prostaglandin E2 (16,16-dimethyl PGE2) is an orally active vertebrate Hematopoietic stem cells (HSCs) homeostasis critical regulator. 16,16-Dimethyl prostaglandin E2 can act through EP2/EP4 and has an interaction with the Wnt pathway .

HY-128454

Dimethyl trisulfide	Environmental Pollutants Biochemical Assay Reagents	Infection Neurological Disease
Dimethyl trisulfide is a cyanide scavenger. Dimethyl trisulfide can be isolated from garlic, onions, broccoli and similar plants. Dimethyl trisulfide converts cyanide into thiocyanate. Dimethyl trisulfide is used by saprophagous insects to locate breeding sites (decaying organic matter), and is also used by deceptive flowers in brood sites to attract such insects. Dimethyl trisulfide induces electrophysiological responses in houseflies .

HY-P2973

Aspergillopepsin I Aspergillus acid protease	Proteasome	Others
Aspergillopepsin I (Aspergillus acid protease) is a metal-containing aspartic protease that catalyzes the hydrolysis of peptide bonds in soybean 7S globulin, soybean 11S globulin and various proteins, with broad specificity. Aspergillopepsin I is intended for use in wine production, where it hydrolyzes haze-forming proteins into small peptides to prevent turbidity during storage. Aspergillopepsin I can be used in studies related to soybean protein hydrolysis and wine production .

HY-W041892

Dimethyl itaconate 1 Publications Verification	Reactive Oxygen Species (ROS)	Infection Neurological Disease Inflammation/Immunology
Dimethyl itaconate induces innate immune memory (trained immunity), and exhibits immunomodulatory property. Dimethyl itaconate inhibits the activation of microglia, reduces the neuroinflammation and synaptic structural damage. Dimethyl itaconate regulates the composition of intestinal flora .

HY-134524

*Isosorbide dimethyl* ether** dimethyl isosorbide; O,O-dimethylisosorbide	Environmental Pollutants Biochemical Assay Reagents	Others
Isosorbide dimethyl ether is a green solvent. Isosorbide dimethyl ether can be used to prepare sustainable ultrafiltration and microfiltration membranes .

HY-W140401

Dimethyl nonanedioate Nonanedioic acid dimethyl ester	Drug Derivative	Metabolic Disease
Dimethyl nonanedioate (Nonanedioic acid dimethyl ester) is an ester product.

HY-Y0749

*Glutamic acid dimethyl* ester hydrochloride** dimethyl (S)-2-aminopentanedioate hydrochloride; dimethyl L-glutamate hydrochloride; dimethyl glutamate hydrochloride	Amino Acid Derivatives	Others
Glutamic acid dimethyl ester hydrochloride is a glutamic acid derivative .

HY-N1789

*Kaempferol-7,4'-dimethyl* ether**	Phosphatase Others	Others
Kaempferol-7,4'-dimethyl ether is a PTP1B inhibitor, and also can inhibit the production of NO. Kaempferol-7,4'-dimethyl ether shows the inhibition rate of 46.1% at 100 μM. Kaempferol-7,4'-dimethyl ether inhibits PTP1B activity with IC50 value of 16.92 μM .

HY-17363S1

Dimethyl fumarate-d2	Autophagy HIV Keap1-Nrf2 Endogenous Metabolite Reactive Oxygen Species (ROS)	Cancer
Dimethyl fumarate-d₂ is the deuterium labeled Dimethyl fumarate . Dimethyl fumarate (DMF) is an orally active and brain-penetrant Nrf2 activator and induces upregulation of antioxidant gene expression. Dimethyl fumarate induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway, and also induces cell autophagy. Dimethyl fumarate can be used for multiple sclerosis research .

HY-W089014

Dimethyl glutarate Pentanedioic acid dimethyl ester	Environmental Pollutants	Metabolic Disease
Dimethyl glutarate (Pentanedioic acid dimethyl ester) is an ester product.

HY-B2062

Chlorthal-dimethyl 1 Publications Verification dimethyl tetrachloroterephthalate	Environmental Pollutants Biochemical Assay Reagents	Others
Chlorthal-dimethyl (Dimethyl tetrachloroterephthalate) is a plant growth regulator. Chlorthal-dimethyl affects cell division and differentiation, interfering with the normal development of vascular tissue. Chlorthal-dimethyl causes localized swelling of tomato hypocotyls and disrupts normal mitosis in germinating millet seedlings .

HY-W460119

Dimethyl pentadecanedioate Pentadecanedioic acid,1,15-dimethyl ester	Drug Derivative	Metabolic Disease
Dimethyl pentadecanedioate (Pentadecanedioic acid,1,15-dimethyl ester) is an ester product.

HY-118452

*cis-3,4',5-Trimethoxy-3'-hydroxystilbene*	Microtubule/Tubulin Apoptosis	Cancer
cis-3,4',5-Trimethoxy-3'-hydroxystilbene is a stilbene. cis-3,4',5-Trimethoxy-3'-hydroxystilbene induces cytochrome c release to the cytoplasm. cis-3,4',5-Trimethoxy-3'-hydroxystilbene-induced apoptosis is associated with mitochondrial release of cytochrome c. cis-3,4',5-Trimethoxy-3'-hydroxystilbene also suppresses tubulin polymerization. cis-3,4',5-Trimethoxy-3'-hydroxystilbene can be used for leukemic research .

HY-17363R

Dimethyl fumarate (Standard)	Reference Standards Keap1-Nrf2 Reactive Oxygen Species (ROS) HIV Autophagy Endogenous Metabolite	Infection Neurological Disease Inflammation/Immunology Cancer
Dimethyl fumarate (Standard) is the analytical standard of Dimethyl fumarate. This product is intended for research and analytical applications. Dimethyl fumarate (DMF) is an orally active and brain-penetrant Nrf2 activator and induces upregulation of antioxidant gene expression. Dimethyl fumarate induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway, and also induces cell autophagy. Dimethyl fumarate can be used for multiple sclerosis research .

HY-W741560

*4,4-Dimethyl* retinoic acid**	Biochemical Assay Reagents
4,4-Dimethyl retinoic acid is a kind of biochemical reagent.

HY-W092607

*Allyl (11S,11aS)-11-((tert-butyldimethylsilyl)oxy)-8-hydroxy-7-methoxy-2-methyl-5-oxo-11,11a-dihydro-1H-benzo[e]pyrrolo[1,2-a][1,4]diazepine-10(5H)-carboxylate*	Drug Intermediate	Others
Allyl (11S,11aS)-11-((tert-butyldimethylsilyl)oxy)-8-hydroxy-7-methoxy-2-methyl-5-oxo-11,11a-dihydro-1H-benzo[e]pyrrolo[1,2-a][1,4]diazepine-10(5H)-carboxylate is a drug intermediate for synthesis of various active compounds.

HY-128454S

Dimethyl trisulfide-d6	Endogenous Metabolite	Others
Dimethyl trisulfide-d6 is deuterium labeled Dimethyl trisulfide (HY-128454). Dimethyl trisulfide is a cyanide antidote .

HY-N12962

11S(12R)-EET	Others	Others
11S(12R)-EET is a dominant enantiomer of epoxytrienoic acid (EET) that is metabolized at a higher rate in rat organs. It shows enantiomeric-dependent reaction selectivity in hydration, especially in the case of 11,12-EET, where water addition is non-regioselective, while in 8,9-EET, water addition occurs mainly at the C9 position. In addition, 11S(12R)-EET generates diol products with specific stereochemistry through enzymatic hydration reactions, which are affected by the selective recognition of epoxidases, reaction conversion rates, and substrate binding parameters .

HY-W015301

Dimethyl adipate Hexanedioic acid dimethyl ester	Environmental Pollutants Drug Intermediate	Others
Dimethyl adipate (Hexanedioic acid dimethyl ester) is an aliphatic dicarboxylate compound. Dimethyl adipate is mainly used as a plasticizer and an intermediate in organic synthesis .

HY-W015301R

Dimethyl adipate (Standard) Hexanedioic acid dimethyl ester (Standard)	Reference Standards Drug Intermediate	Others
Dimethyl adipate (Hexanedioic acid dimethyl ester) (Standard) is the analytical standard of Dimethyl adipate (HY-W015301). This product is intended for research and analytical applications. Dimethyl adipate is an aliphatic dicarboxylate compound. Dimethyl adipate is mainly used as a plasticizer and an intermediate in organic synthesis.

HY-B2062R

*Chlorthal-dimethyl* (Standard)** dimethyl tetrachloroterephthalate (Standard)	Drug Intermediate Mitosis Reference Standards	Others
Chlorthal-dimethyl (Standard) is the analytical standard of Chlorthal-dimethyl. This product is intended for research and analytical applications. Chlorthal-dimethyl (Dimethyl tetrachloroterephthalate) is a plant growth regulator. Chlorthal-dimethyl affects cell division and differentiation, interfering with the normal development of vascular tissue. Chlorthal-dimethyl causes localized swelling of tomato hypocotyls and disrupts normal mitosis in germinating millet seedlings .

HY-W008294

*3-Hydroxyglutaric acid dimethyl* ester** Pentanedioic acid, 3-hydroxy-, dimethyl ester	Drug Derivative	Others
3-Hydroxyglutaric acid dimethyl ester (Pentanedioic acid, 3-hydroxy-, dimethyl ester) is a prochiral substrate and an esterified derivative of 3-Hydroxyglutaric acid (HY-113411).

HY-P4308

*Z-Pro-Pro-aldehyde-dimethyl* acetal**	Prolyl Endopeptidase (PREP)	Neurological Disease
Z-Pro-Pro-aldehyde-dimethyl acetal is a potent inhibitor of prolyl endopeptidase (PREP), a cytoplasmic serine endoprotease (IC₅₀= 12 nM). Z-Pro-Pro-aldehyde-dimethyl acetal plays an important role in cognitive dysfunction in aging and neurodegenerative diseases including Alzheimer's disease .

HY-N8621

*(11S)-(-)-Hydroxyjasmonic acid*	Drug Isomer	Others
(11S)-(-)-Hydroxyjasmonic acid is a hydroxylated cyclopentane fatty acid of the jasmonic acid type that can be found in the culture filtrate of the fungus Botryodiplodia theobromae< .

HY-27980

Trimethoxy(4-phenylbutyl)silane	Drug Intermediate	Others
Trimethoxy(4-phenylbutyl)silane is a drug intermediate for synthesis of various active compounds.

HY-W001472

Dimethyl pimelate Pimelic acid dimethyl ester	Drug Derivative	Metabolic Disease
Dimethyl pimelate (Pimelic acid dimethyl ester) is an ester product.

HY-P6053

KK-103	Opioid Receptor	Neurological Disease
KK-103 is a precursor of leucine-enkephalin (Leu-ENK) overcomes high proteolytic instability of Leu-ENK via markedly increased plasma stability in mice that has antinociceptive effect .

HY-W098048

Dimethyl hexadecanedioate Hexadecanedioic acid,dimethyl ester	Drug Derivative	Metabolic Disease
Dimethyl hexadecanedioate (Hexadecanedioic acid,dimethyl ester) is an ester product.

HY-W098047

Dimethyl octadecanedioate Octadecanedioic acid,dimethyl ester	Drug Derivative	Metabolic Disease
Dimethyl octadecanedioate (Octadecanedioic acid,dimethyl ester) is an ester product.

HY-W037817

Dimethyl L-glutamate dimethyl glutamate	Potassium Channel Bacterial	Infection Metabolic Disease
Dimethyl L-glutamate (Dimethyl glutamate), a membrane-permeable analog of Glutamate, can stimulate insulin release induced by Glucose. Dimethyl L-glutamate suppresses the K_ATP channel activities. Dimethyl L-glutamate inhibits E. gracilis growth and causes abnormal cell division. Dimethyl L-glutamate can be used in the research of diabetes, glucose transport, phosphorylation, and further metabolism .

HY-W653780

Dimethyl phosphorothioate DMTP; O,O-dimethyl phosphorothionate	Endogenous Metabolite	Others
Dimethyl phosphorothioate (DMTP; O,O-Dimethyl phosphorothionate) is a metabolite of organophosphate pesticides. Dimethyl phosphorothioate can be used as a biomonitoring indicator for assessing pesticide exposure levels of organophosphate pesticides and identifying high-risk groups .

HY-145477

*8(R),11(S)-DiHODE*	Drug Intermediate	Metabolic Disease
8(R),11(S)-DiHODE is a fungal oxylipin that has been found in Aspergillus .

HY-W004545

*6,6'-Dimethyl-2,2'-bipyridyl* 6,6'-dimethyl-2,2'-bipyridine	MOFs	Others
6,6'-Dimethyl-2,2'-bipyridyl (6,6'-Dimethyl-2,2'-bipyridine) is a metal-organic framework (MOF).

HY-Y1787R

Dimethyl malonate (Standard)	Reference Standards Apoptosis	Neurological Disease
Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase (SDH). Dimethyl malonate is able to cross the blood-brain barrier and hydrolyse to malonate. Dimethyl malonate reduces neuronal apoptosis .

HY-126678

Dimethyl-SGD-1882 dimethyl-PBD dimer	ADC Payload	Cancer
Dimethyl-SGD-1882 (Dimethyl-PBD dimer) is a highly potent DNA alkylator, and is used as an antibody-drug conjugate (ADC) cytotoxin. PBD Dimer is a DNA alkylator which inhibits DNA replication .

HY-W013359

Dimethyl dodecanedioate	Drug Derivative	Metabolic Disease
Dimethyl dodecanedioate is an ester product.

HY-W010553

*2,5-Dimethyl-3(2H)-furanone* 2,5-dimethyl-2,3-dihydrofuran-3-one	Biochemical Assay Reagents	Others
2,5-Dimethyl-3(2H)-furanone (2,5-Dimethyl-2,3-dihydrofuran-3-one) is a type of furanone-based fragrance compound. 2,5-Dimethyl-3(2H)-furanone has no ability to damage DNA and no genetic toxicity .

HY-P6177

SGP8	Dipeptidyl Peptidase	Inflammation/Immunology
SGP8 (IAVPGEVA) is an octapeptide produced by hydrolysis of soybean 11S globulin, which has the effects of regulating lipid metabolism, inflammation and fibrosis. SGP8 (IAVPGEVA) exhibits inhibitory activity against DPP4 and inhibits the JNK-c-Jun signaling pathway, and has the ability to inhibit non-alcoholic steatohepatitis (NASH) .

HY-162631

IDH1 Inhibitor 9	Apoptosis Isocitrate Dehydrogenase (IDH)	Cancer
IDH1 Inhibitor 9 (compound 11S) is a potent IDH1 inhibitor with IC₅₀ values of 124.4, 95.7 nM for IDH1 R132H, IDH1 R132C, respectively. IDH1 Inhibitor 9 induces apoptosis and cell cycle arrest at the S phase. IDH1 Inhibitor 9 shows anti-tumor activity .

HY-N12738

*2′,4′,6′-Trimethoxy-3′-methylacetophenone*	Others	Others
2′,4′,6′-Trimethoxy-3′-methylacetophenone (compound 15) is a rosin lactone that can be isolated from E. portulacoides .

HY-N1024A

11S,12-Dihydroxyspirovetiv-1(10)-en-2-one	Others	Others
11S,12-Dihydroxyspirovetiv-1(10)-en-2-one is a Sesquiterpenoids product that can be isolated from the herbs of Datura metel .

HY-N10261

Methyl 3,4,5-trimethoxy-2-(2-(nicotinamido)benzamido)benzoate	Endogenous Metabolite	Others
Methyl 3,4,5-trimethoxy-2-(2-(nicotinamido)benzamido)benzoate is a fungal metabolite .

HY-N9101

*4,4'-Dihydroxy-3,3',9-trimethoxy-9,9'-epoxylignan*	Others	Cancer
4,4'-Dihydroxy-3,3',9-trimethoxy-9,9'-epoxylignan is a lignans that can be isolated from the Viburnum foetidum. 4,4'-Dihydroxy-3,3',9-trimethoxy-9,9'-epoxylignan has cytotoxicity against A549, SK-OV-3, SKMEL-2 and HCT15 cell line with IC₅₀s of 67.14, 67.38, 64.11 and 76.31 μg/mL, respectively .

HY-N9193

*2',4',5'-Trimethoxy-2'',2''-dimethylpyrano[5'',6'':6,7]isoflavone*	Biochemical Assay Reagents	Others
2',4',5'-Trimethoxy-2'',2''-dimethylpyrano[5'',6'':6,7]isoflavone is an isoflavone .

HY-N15693

*2-O-B-D-Glucopyranosyloxy-1,7,8-trimethoxy- 3-methylanthraquinone*	Biochemical Assay Reagents	Infection Inflammation/Immunology
2-O-B-D-Glucopyranosyloxy-1,7,8-trimethoxy-3-methylanthraquinone can be found in the seeds of Cassia obtusifolia .

HY-N12006

*6,8-Dihydroxy-1,2,7-trimethoxy-3-methylanthraquinone*	Glycosidase	Others
6,8-Dihydroxy-1,2,7-trimethoxy-3-methylanthraquinone (compound 1) is an anthraquinone α-glucosidase inhibitor (IC₅₀:185 μM), which can be isolated from Cassia seeds .

Cat. No.	Product Name	Type

HY-44134

Dimethyl 2-oxoglutarate

1 Publications Verification

dimethyl α-ketoglutarate

Biochemical Assay Reagents

Dimethyl 2-oxoglutarate (Dimethyl α-ketoglutarate) is a cell-permeable derivative of 2-oxoglutarate and tricarboxylic acid cycle metabolite with antioxidant properties. Dimethyl 2-oxoglutarate inhibits Autophagy. Dimethyl 2-oxoglutarate prevents mitochondrial damage and reduces ROS production. Dimethyl 2-oxoglutarate alleviates Carbon tetrachloride (HY-Y0298)-induced liver fibrosis. Dimethyl-2-oxoglutaric acid can be used in the research of diseases such as Alzheimer's disease, diabetes, and cardiomyopathy .

HY-Y0808

Dimethyl succinate

1 Publications Verification

Biochemical Assay Reagents

Dimethyl succinate is an orally active cell permeable succinate analogue. Dimethyl succinate can disrupt the TCA cycle by elevating intracellular succinate levels, leading to reduced protein synthesis and impairs myogenic differentiation. Dimethyl succinate can induce apoptosis. Dimethyl succinate can decrease maximal cellular respiration and reserve capacity. Dimethyl succinate can rescue synapse loss in AD. Dimethyl succinate can be used for the researches of metabolic and neurological disease ^[1][2].

HY-W041892

Dimethyl itaconate 1 Publications Verification	Biochemical Assay Reagents
Dimethyl itaconate induces innate immune memory (trained immunity), and exhibits immunomodulatory property. Dimethyl itaconate inhibits the activation of microglia, reduces the neuroinflammation and synaptic structural damage. Dimethyl itaconate regulates the composition of intestinal flora .

HY-W741560

*4,4-Dimethyl* retinoic acid**	Biochemical Assay Reagents
4,4-Dimethyl retinoic acid is a kind of biochemical reagent.

HY-W072979

*Mesoporphyrin dimethyl* ester** Mesoporphyrin IX dimethyl ester	Biochemical Assay Reagents
Mesoporphyrin dimethyl ester (Mesoporphyrin IX dimethyl ester) is a biochemical reagent .

HY-W015028R

Dimethyl isophthalate (Standard)	Biochemical Assay Reagents
Dimethyl isophthalate (Standard) is the analytical standard of Dimethyl isophthalate. This product is intended for research and analytical applications. Dimethyl isophthalate is a kind of biological materials or organic compounds that are widely used in life science research .

HY-Y0383R

Dimethyl terephthalate (Standard)	Biochemical Assay Reagents
Dimethyl terephthalate (Standard) is the analytical standard of Dimethyl terephthalate. This product is intended for research and analytical applications. Dimethyl terephthalate is a low toxicity, low volatility industrial chemical widely used in the production of polyester fibers and films .

Cat. No.	Product Name	Target	Research Area

HY-Y0749

*Glutamic acid dimethyl* ester hydrochloride** dimethyl (S)-2-aminopentanedioate hydrochloride; dimethyl L-glutamate hydrochloride; dimethyl glutamate hydrochloride	Amino Acid Derivatives	Others
Glutamic acid dimethyl ester hydrochloride is a glutamic acid derivative .

HY-P4308

*Z-Pro-Pro-aldehyde-dimethyl* acetal**	Prolyl Endopeptidase (PREP)	Neurological Disease
Z-Pro-Pro-aldehyde-dimethyl acetal is a potent inhibitor of prolyl endopeptidase (PREP), a cytoplasmic serine endoprotease (IC₅₀= 12 nM). Z-Pro-Pro-aldehyde-dimethyl acetal plays an important role in cognitive dysfunction in aging and neurodegenerative diseases including Alzheimer's disease .

HY-P6053

KK-103	Opioid Receptor	Neurological Disease
KK-103 is a precursor of leucine-enkephalin (Leu-ENK) overcomes high proteolytic instability of Leu-ENK via markedly increased plasma stability in mice that has antinociceptive effect .

HY-W037817

Dimethyl L-glutamate dimethyl glutamate	Potassium Channel Bacterial	Infection Metabolic Disease
Dimethyl L-glutamate (Dimethyl glutamate), a membrane-permeable analog of Glutamate, can stimulate insulin release induced by Glucose. Dimethyl L-glutamate suppresses the K_ATP channel activities. Dimethyl L-glutamate inhibits E. gracilis growth and causes abnormal cell division. Dimethyl L-glutamate can be used in the research of diabetes, glucose transport, phosphorylation, and further metabolism .

HY-P6177

SGP8	Dipeptidyl Peptidase	Inflammation/Immunology
SGP8 (IAVPGEVA) is an octapeptide produced by hydrolysis of soybean 11S globulin, which has the effects of regulating lipid metabolism, inflammation and fibrosis. SGP8 (IAVPGEVA) exhibits inhibitory activity against DPP4 and inhibits the JNK-c-Jun signaling pathway, and has the ability to inhibit non-alcoholic steatohepatitis (NASH) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-44134

Dimethyl 2-oxoglutarate 1 Publications Verification dimethyl α-ketoglutarate	Structural Classification Natural Products Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Drug Derivative Autophagy Mitochondrial Metabolism Reactive Oxygen Species (ROS)
Dimethyl 2-oxoglutarate (Dimethyl α-ketoglutarate) is a cell-permeable derivative of 2-oxoglutarate and tricarboxylic acid cycle metabolite with antioxidant properties. Dimethyl 2-oxoglutarate inhibits Autophagy. Dimethyl 2-oxoglutarate prevents mitochondrial damage and reduces ROS production. Dimethyl 2-oxoglutarate alleviates Carbon tetrachloride (HY-Y0298)-induced liver fibrosis. Dimethyl-2-oxoglutaric acid can be used in the research of diseases such as Alzheimer's disease, diabetes, and cardiomyopathy .

HY-17363

Dimethyl fumarate Maximum Cited Publications 56 Publications Verification	Infection Natural Products Neurological Disease Classification of Application Fields Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Keap1-Nrf2 Reactive Oxygen Species (ROS) HIV Autophagy Endogenous Metabolite
Dimethyl fumarate (DMF) is an orally active and brain-penetrant Nrf2 activator and induces upregulation of antioxidant gene expression. Dimethyl fumarate induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway, and also induces cell autophagy. Dimethyl fumarate can be used for multiple sclerosis research .

HY-Y1787

Dimethyl malonate 5+ Cited Publications	Structural Classification Natural Products Melia azedarach L. Plants Meliaceae Source Classification	Apoptosis
Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase (SDH). Dimethyl malonate is able to cross the blood-brain barrier and hydrolyse to malonate. Dimethyl malonate reduces neuronal apoptosis .

HY-128454

Dimethyl trisulfide	Structural Classification Natural Products Microorganisms Liliaceae Classification of Application Fields Other Diseases Plants Endogenous metabolite Disease Research Fields A．Sativam L. var．Viviparum Regel Source Classification	Environmental Pollutants Biochemical Assay Reagents
Dimethyl trisulfide is a cyanide scavenger. Dimethyl trisulfide can be isolated from garlic, onions, broccoli and similar plants. Dimethyl trisulfide converts cyanide into thiocyanate. Dimethyl trisulfide is used by saprophagous insects to locate breeding sites (decaying organic matter), and is also used by deceptive flowers in brood sites to attract such insects. Dimethyl trisulfide induces electrophysiological responses in houseflies .

HY-N1789

*Kaempferol-7,4'-dimethyl* ether**	Flavonols Monophenols Flavonoids Tamaricaceae Classification of Application Fields Tamarix chinensis Lour. Other Diseases Phenols Plants Disease Research Fields Source Classification	Phosphatase Others
Kaempferol-7,4'-dimethyl ether is a PTP1B inhibitor, and also can inhibit the production of NO. Kaempferol-7,4'-dimethyl ether shows the inhibition rate of 46.1% at 100 μM. Kaempferol-7,4'-dimethyl ether inhibits PTP1B activity with IC50 value of 16.92 μM .

HY-17363R

Dimethyl fumarate (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Reference Standards Keap1-Nrf2 Reactive Oxygen Species (ROS) HIV Autophagy Endogenous Metabolite
Dimethyl fumarate (Standard) is the analytical standard of Dimethyl fumarate. This product is intended for research and analytical applications. Dimethyl fumarate (DMF) is an orally active and brain-penetrant Nrf2 activator and induces upregulation of antioxidant gene expression. Dimethyl fumarate induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway, and also induces cell autophagy. Dimethyl fumarate can be used for multiple sclerosis research .

HY-N12962

11S(12R)-EET	Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Others
11S(12R)-EET is a dominant enantiomer of epoxytrienoic acid (EET) that is metabolized at a higher rate in rat organs. It shows enantiomeric-dependent reaction selectivity in hydration, especially in the case of 11,12-EET, where water addition is non-regioselective, while in 8,9-EET, water addition occurs mainly at the C9 position. In addition, 11S(12R)-EET generates diol products with specific stereochemistry through enzymatic hydration reactions, which are affected by the selective recognition of epoxidases, reaction conversion rates, and substrate binding parameters .

HY-Y1787R

Dimethyl malonate (Standard)	Structural Classification Natural Products Melia azedarach L. Plants Meliaceae Source Classification	Reference Standards Apoptosis
Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase (SDH). Dimethyl malonate is able to cross the blood-brain barrier and hydrolyse to malonate. Dimethyl malonate reduces neuronal apoptosis .

HY-N12738

*2′,4′,6′-Trimethoxy-3′-methylacetophenone*	Natural Products Euphorbia portulacoides L. Euphorbiaceae Plants Source Classification	Others
2′,4′,6′-Trimethoxy-3′-methylacetophenone (compound 15) is a rosin lactone that can be isolated from E. portulacoides .

HY-N1024A

11S,12-Dihydroxyspirovetiv-1(10)-en-2-one	Terpenoids Sesquiterpenes Datura metel L. Solanaceae Plants Source Classification	Others
11S,12-Dihydroxyspirovetiv-1(10)-en-2-one is a Sesquiterpenoids product that can be isolated from the herbs of Datura metel .

HY-N10261

Methyl 3,4,5-trimethoxy-2-(2-(nicotinamido)benzamido)benzoate	Alkaloids Microorganisms Classification of Application Fields Other Diseases Pyridine Alkaloids Disease Research Fields Source Classification	Endogenous Metabolite
Methyl 3,4,5-trimethoxy-2-(2-(nicotinamido)benzamido)benzoate is a fungal metabolite .

HY-N9101

*4,4'-Dihydroxy-3,3',9-trimethoxy-9,9'-epoxylignan*	Caprifoliaceae Lignans Phenylpropanoids Viburnum cylindricum Buch.-Ham. ex D. Don Plants Source Classification	Others
4,4'-Dihydroxy-3,3',9-trimethoxy-9,9'-epoxylignan is a lignans that can be isolated from the Viburnum foetidum. 4,4'-Dihydroxy-3,3',9-trimethoxy-9,9'-epoxylignan has cytotoxicity against A549, SK-OV-3, SKMEL-2 and HCT15 cell line with IC₅₀s of 67.14, 67.38, 64.11 and 76.31 μg/mL, respectively .

HY-N15693

*2-O-B-D-Glucopyranosyloxy-1,7,8-trimethoxy- 3-methylanthraquinone*	Quinones Anthraquinones Caesalpiniaceae Cassia obtusifolia (L.) H. S. Irwin & Barneby Plants Source Classification	Biochemical Assay Reagents
2-O-B-D-Glucopyranosyloxy-1,7,8-trimethoxy-3-methylanthraquinone can be found in the seeds of Cassia obtusifolia .

HY-N12006

*6,8-Dihydroxy-1,2,7-trimethoxy-3-methylanthraquinone*	Quinones Anthraquinones Caesalpiniaceae Cassia obtusifolia (L.) H. S. Irwin & Barneby Plants Source Classification	Glycosidase
6,8-Dihydroxy-1,2,7-trimethoxy-3-methylanthraquinone (compound 1) is an anthraquinone α-glucosidase inhibitor (IC₅₀:185 μM), which can be isolated from Cassia seeds .

HY-N12870

*(7S,8R)-4,9,9'-Trihydroxy-3,3',5-trimethoxy-8,4'-oxyneolignan 4-O-β-D-glucopyranoside*	Smilacaceae Lignans Phenylpropanoids Plants Smilax trinervula Miq. Source Classification	Others
(7S,8R)-4,9,9'-Trihydroxy-3,3',5-trimethoxy-8,4'-oxyneolignan 4-O-β-D-glucopyranoside (5) is a lignan compound that can be isolated from Smilax trinervula .

HY-128454R

Dimethyl trisulfide (Standard)	Structural Classification Natural Products Microorganisms Liliaceae Plants Endogenous metabolite A．Sativam L. var．Viviparum Regel Source Classification	Reference Standards Endogenous Metabolite
Dimethyl trisulfide (Standard) is the analytical standard of Dimethyl trisulfide. This product is intended for research and analytical applications. Dimethyl trisulfide is an organic chemical compound and the simplest organic trisulfide found in garlic, onion, broccoli, and similar plants. Dimethyl trisulfide is a cyanide antidote. Dimethyl trisulfide formation requires the thermal degradation of Met .

HY-N12274

*Quercetin 5,3′-dimethyl* ether**	Flavonols Flavonoids Combretaceae Plants Combretum erythrophyllum Sond. Source Classification	Others
Quercetin 5,3′-dimethyl ether is a kind of flavonoid. Quercetin 5,3′-dimethyl ether can be isolated from Combretum erythrophyllum (Combretaceae). Quercetin 5,3′-dimethyl ether has anti-inflammatory activity and antibacterial activity .

HY-W720042A

*(rac)-Zeaxanthin dimethyl* ether**	Natural Products Microorganisms Source Classification	Biochemical Assay Reagents
(rac)-Zeaxanthin dimethyl ether is the racemate of Zeaxanthin dimethyl ester. Zeaxanthin is a type of xanthophyll. (rac)-Zeaxanthin dimethyl ether has applications as pharmaceuticals and nutraceuticals and in the food industry .

HY-N10356

*4,27-Dimethyl* withaferin A**	Withania somnifera Solanaceae Plants Steroids Source Classification	Others
4,27-Dimethyl withaferin A is a synthetic analog of withanolide natural products. 4,27-Dimethyl withaferin A has the potential for the research of neurodegenerative diseases (extracted from patent WO2015077780A1) .

HY-Y1314R

Dimethyl sulfone (Standard)	Structural Classification Natural Products Microorganisms Endogenous metabolite Source Classification	Drug Metabolite Reference Standards Endogenous Metabolite
Dimethyl sulfone (Standard) is the analytical standard of Dimethyl sulfone. This product is intended for research and analytical applications. Dimethyl sulfone (Methyl Sulfonyl Methane) is a metabolic product of endogenous methanethiol metabolism and intestinal bacterial metabolism. Dimethyl sulfone inhibits choriocapillary endothelial (CCE) cell proliferation, also has many biological effects, including antiinflammatory, antioxidant, and local anesthetic effects that could be neuroprotective .

HY-N8782

*4,6,7-Trimethoxy-5-methylcoumarin*	Viola philippica Cav. Coumarins Phenylpropanoids Violaceae Plants Source Classification	Others
4,6,7-Trimethoxy-5-methylcoumarin is a Coumarins product that can be isolated from the herbs of Viola yedonensis Makino .

HY-N2657

*Flavone, 5,7-dihydroxy-3,4',8-trimethoxy-, diacetate*	Flavonoids Flavones Rutaceae Micromelum integerrimum (Buch.-Ham.) Roem. Plants Source Classification	Others
Flavone, 5,7-dihydroxy-3,4',8-trimethoxy-, diacetate is a Flavonoids product that can be isolated from the herbs of Micromelum sp. .

HY-N13326

*3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan*	Lignans Phenylpropanoids Plants Acacia confusa Merr. Compositae Source Classification	Others
3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan is a natural product .

HY-180569

11(S)-HPODE	Structural Classification Natural Products Endogenous metabolite Source Classification	Nucleoside Antimetabolite/Analog
11(S)-HPODE is a nucleoside metabolite.

HY-N17846

Dimethyl lithospermate	Structural Classification Labiatae Samanea saman (Jacq.) Merr. Phenols Polyphenols Plants Source Classification	Reactive Oxygen Species (ROS)
Dimethyl lithospermate is an antioxidant. Dimethyl lithospermate scavenges DPPH free radicals and inhibits free radical generation. Dimethyl lithospermate also protects hepatocytes from tert-butyl hydroperoxide (t-BHP)-induced oxidative damage. Dimethyl lithospermate can be used in oxidative damage-related research .

HY-N19784

*12,13-Dimethyl* chebulate**	Structural Classification Dipteronia dyeriana Henry Ketones, Aldehydes, Acids Sapindaceae Plants Source Classification	Fungal
12,13-Dimethyl chebulate is a methylated chebulic acid derivative that can be found in sugar maple fall leaves and Terminalia dhofarica leaves. 12,13-Dimethyl chebulate exhibits antifungal activity and DPPH scavenging activity. 12,13-Dimethyl chebulate can be used for the research of fungal infection .

HY-N19785

*11,12-Dimethyl* chebulate**	Structural Classification Dipteronia dyeriana Henry Ketones, Aldehydes, Acids Sapindaceae Plants Source Classification	Fungal
11,12-Dimethyl chebulate is a phenolic acid chebulate derivative that can be found in Acer saccharum fall leaves and Terminalia dhofarica leaf extracts. 11,12-Dimethyl exhibits antifungal activity and DPPH scavenging activity.11,12-Dimethyl chebulate can be used for the research of fungal infection .

HY-N18014

*Naringenin 4',7-dimethyl* ether**	Structural Classification Flavonoids Pistacia chinensis Bunge Flavonones Plants Anacardiaceae Source Classification	Drug Derivative
Naringenin 4',7-dimethyl ether, Naringenin (HY-N0100) derivative is an anti-seizure agent. Naringenin 4',7-dimethyl ether attenuates pentylenetetrazole-induced seizures in larval zebrafish and reduces seizures in the mouse 6-Hz psychomotor seizure model. Naringenin 4',7-dimethyl ether can be used for the research of epilepsy .

Species:	Human (11) Mouse (4) Cynomolgus (2)
Tag:	His (12) Tag Free (2) Avi (2) Fc (4)
Source:	HEK293 (11) E. coli (7)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P78333

	OSMR beta Protein, Mouse (HEK293, His) IL-31r subunit beta; IL-31r-beta; IL-31rB; OSMR beta; OSMR; OSMRB; OSMRBMGC150626; PLCA1 ; IL-31r subunit β; IL-31r-β; OSMR β	Mouse	HEK293
	The OSMR beta Protein, in partnership with IL31RA, constitutes the IL31 receptor, binding IL31 to activate STAT3, and potentially STAT1 and STAT5.OSMR beta also transduces OSM-specific signaling.It forms a heterodimer with IL6ST, creating the type II OSM receptor, and another heterodimer with IL31RA for the IL31 receptor.OSMR beta Protein, Mouse (HEK293, His) is the recombinant mouse-derived OSMR beta protein, expressed by HEK293 , with C-His labeled tag.

HY-P700806

	OSMR beta Protein, Cynomolgus (HEK293, His) IL-31r subunit beta; IL-31r-beta; IL-31rB; OSMR beta; OSMR; OSMRB; OSMRBMGC150626; PLCA1 ; IL-31r subunit β; IL-31r-β; OSMR β	Cynomolgus	HEK293
	OSMR beta protein is a type I cytokine receptor in the type 2 subfamily and is critical in cell signaling and immune responses. OSMR beta serves as a receptor for oncostatin M, a cytokine that plays a role in inflammation, cell growth, and differentiation, and is critical for downstream signaling and regulation of cell function. OSMR beta Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived OSMR beta protein, expressed by HEK293 , with C-His labeled tag.

HY-P75859

	*IL-31R* alpha Protein, Human (HEK293, Fc)** Interleukin-31 receptor subunit alpha; IL-31r-alpha; IL-31rA; GLM-R; GLM-R; CRL3	Human	HEK293
	IL-31R alpha protein binds to IgM heavy and light chains and helps IgM assembly and secretion. It can act as a molecular chaperone or an oxidoreductase, exhibiting low oxidoreductase activity. IL-31R alpha Protein, Human (HEK293, Fc) is the recombinant human-derived IL-31R alpha protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P75860

	*IL-31R* alpha Protein, Human (HEK293, His)** Interleukin-31 receptor subunit alpha; IL-31r-alpha; IL-31rA; GLM-R; GLM-R; CRL3	Human	HEK293
	IL-31R alpha protein binds to IgM heavy and light chains and helps IgM assembly and secretion. It can act as a molecular chaperone or an oxidoreductase, exhibiting low oxidoreductase activity. IL-31R alpha Protein, Human (HEK293, His) is the recombinant human-derived IL-31R alpha protein, expressed by HEK293 , with C-His labeled tag.

HY-P704146

	*IL-31R* alpha Protein, Cynomolgus (HEK293, His)** Interleukin-31 receptor subunit alpha; IL-31r-alpha; IL-31rA; GLM-R; GLM-R; CRL3	Cynomolgus	HEK293
	IL-31R alpha Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IL-31R alpha protein, expressed by HEK293, with C-His tag.

HY-P705228

	*IL-31R* alpha Protein, Human (Biotinylated, HEK293, Fc-Avi)** Interleukin-31 receptor subunit alpha; IL-31r-alpha; IL-31rA; GLM-R; GLM-R; CRL3	Human	HEK293

HY-P77968

	*IL-31R* alpha Protein, Mouse (HEK293, His)** IL-31rA; IL-31r-alpha; Gp130-like receptor; CRL3; GPL; ZcytoR17; GLM-R; CRL3Glmr; GLM-RMGC125346; PRO21384	Mouse	HEK293
	The IL-31R alpha protein is critical to the immune response and forms the interleukin 31 receptor with OSMR. It activates STAT3, and to a lesser extent STAT1 and STAT5, is associated with skin immunity and mediates IL31-induced itch, possibly involving the cation channels TRPA1 and TRPV1. IL-31R alpha Protein, Mouse (HEK293, His) is the recombinant mouse-derived IL-31R alpha protein, expressed by HEK293 , with a C-His labeled tag.

HY-P704713

	*IL-31R* alpha Protein, Mouse (HEK293, hFc)** IL-31rA; IL-31r-alpha; Gp130-like receptor; CRL3; GPL; ZcytoR17; GLM-R; CRL3Glmr; GLM-RMGC125346; PRO21384	Mouse	HEK293
	The IL-31R alpha protein is critical to the immune response and forms the interleukin 31 receptor with OSMR. It activates STAT3, and to a lesser extent STAT1 and STAT5, is associated with skin immunity and mediates IL31-induced itch, possibly involving the cation channels TRPA1 and TRPV1. IL-31R alpha Protein, Mouse (HEK293, hFc) is the recombinant mouse-derived IL-31R alpha protein, expressed by HEK293, with C-hFc labeled tag.

HY-P74586

	S100A10 Protein, Human (His) Protein S100-A10; p11; S100A10; ANX2LG; CAL1L; CLP11	Human	E. coli
	S100A10 Protein is pivotal in modulating protein phosphorylation by promoting ANXA2/p36 dimerization. The ANXA2 monomer is the favored substrate for tyrosine-specific kinase activity in vitro. A heterotetramer, composed of S100A10/p11 and ANXA2/p36, highlights intricate regulatory dynamics. This interaction landscape includes SCN10A and TASOR, showcasing S100A10's multifaceted involvement in cellular processes. S100A10 Protein, Human (His) is the recombinant human-derived S100A10 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P72500

	OSMR beta Protein, Human (HEK293, His) Oncostatin-M-specific receptor subunit beta; IL-31r-beta; IL-31rB; OSMR; OSMRB	Human	HEK293
	The OSMR beta protein is critical in immune responses by binding to IL12RB1 to form the interleukin 23 receptor with IL-23R. It binds to IL23 and activates T cells, NK cells and potentially macrophages/myeloid cells through Jak-Stat signaling. OSMR beta Protein, Human (712a.a, HEK293, His) is the recombinant human-derived OSMR beta protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P71269

	S100A11 Protein, Mouse (His) Protein S100-A11; Calgizzarin; Endothelial monocyte-activating polypeptide; EMAP; Protein S100-C; S100 calcium-binding protein A11; S100a11; S100c	Mouse	E. coli
	The S100A11 protein plays a crucial role in promoting keratinocyte differentiation and keratinization, suggesting its involvement in important processes related to skin development and integrity.As a disulfide-linked homodimer, S100A11 may contribute to the molecular machinery that regulates keratinocyte maturation and specialized functions.S100A11 Protein, Mouse (His) is the recombinant mouse-derived S100A11 protein, expressed by E.coli , with N-6*His labeled tag.

HY-P72482

	S100A11 Protein, Human Protein S100-A11; Calgizzarin; MLN 70; Protein S100-C; S100A11	Human	E. coli
	S100A11 Protein facilitates keratinocyte differentiation and cornification, forming homodimers via disulfide linkages. S100A11 Protein, Human is the recombinant human-derived S100A11 protein, expressed by E. coli , with tag free.

HY-P70419

	LRRC32 Protein, Human (HEK293, Fc) rHuTransforming growth factor beta activator LRRC32/LRRC32, Fc; GARP; GARPGarpin; Garpin; D11s833E	Human	HEK293
	LRRC32 is a key regulator of TGF-β activation and maintains TGFB1, TGFB2, and TGFB3 in the latent state during extracellular storage by binding to latency-associated peptide (LAP). LRRC32 competes with LTBP1 for LAP binding and effectively regulates integrin-dependent TGF-β activation. LRRC32 Protein, Human (HEK293, Fc) is the recombinant human-derived LRRC32 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P701616

	PHF8 Protein, Human PHF8; Histone lysine demethylase PHF8; PHD finger protein 8; [histone H3]-dimethyl-L-lysine(36) demethylase PHF8; [histone H3]-dimethyl-L-lysine(9) demethylase PHF8	Human	E. coli
	The PHF8 protein is a histone lysine demethylase that plays a key role in cell cycle progression, rDNA transcription, and brain development. It selectively demethylates H3 'Lys-9' (H3K9Me1 and H3K9Me2), H3 'Lys-27' (H3K27Me2) and H4 'Lys-20' (H4K20Me1). PHF8 Protein, Human is the recombinant human-derived PHF8 protein, expressed by E. coli , with tag free.

HY-P701617

	PHF8 Protein, Human (His) PHF8; Histone lysine demethylase PHF8; PHD finger protein 8; [histone H3]-dimethyl-L-lysine(36) demethylase PHF8; [histone H3]-dimethyl-L-lysine(9) demethylase PHF8	Human	E. coli
	The PHF8 protein is a histone lysine demethylase that plays a key role in cell cycle progression, rDNA transcription, and brain development. It selectively demethylates H3 'Lys-9' (H3K9Me1 and H3K9Me2), H3 'Lys-27' (H3K27Me2) and H4 'Lys-20' (H4K20Me1). PHF8 Protein, Human (His) is the recombinant human-derived PHF8 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P702176

	MDO Protein, Mycobacterium sp. (His) Methanol:N; N-dimethyl-4-nitrosoaniline oxidoreductase; MDO; Methanol dehydrogenase (nicotinoprotein); Methanol:NDMA oxidoreductase	Others	E. coli
	MDO (methanol dehydrogenase) is responsible for oxidizing methanol to produce formaldehyde. Although the in vivo electron acceptor remains unidentified, in vitro experiments indicate that N,N-dimethyl-4-nitrosaniline (NDMA) can serve as a suitable electron acceptor and is subsequently reduced to 4-(hydroxyamino) -N,N-Dimethylaniline. MDO Protein, Mycobacterium sp. (His) is the recombinant MDO protein, expressed by E. coli , with N-6*His labeled tag.

HY-P700857

	GARP&Latent TGF Beta 2 Complex Protein, Human (HEK293, His-Avi) Garpin; GARP; LRRC32; D11s833E; GARP&Latent TGF B; GARP&TGF B; Cetermin; G-TSF; LAP; TGF-beta-2; TGF Beta 2; GARP&Latent TGF Beta 2	Human	HEK293
	LRRC32 is a key regulator of TGF-β activation and maintains TGFB1, TGFB2, and TGFB3 in the latent state during extracellular storage by binding to latency-associated peptide (LAP). LRRC32 competes with LTBP1 for LAP binding and effectively regulates integrin-dependent TGF-β activation. GARP&Latent TGF Beta 2 Complex Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived GARP&Latent TGF Beta 2 Complex protein, expressed by HEK293 , with C-Avi, C-His labeled tag. GARP&Latent TGF Beta 2 Complex Protein, Human (HEK293, His-Avi), has molecular weight of 72-77 kDa(GARP) & 13 kDa & 46-48 kDa(Latent TGF Beta 2), respectively.

HY-P72119

	CCND1 Protein, Human (His) AI327039; B cell leukemia 1; B-cell lymphoma 1 protein; BCL 1; BCL-1; BCL-1 oncogene; BCL1; BCL1 oncogene; ccnd1; CCND1/FSTL3 fusion gene; CCND1/FSTL3 fusion gene; included; CCND1/IGHG1 fusion gene; CCND1/IGLC1 fusion gene; CCND1_HUMAN; cD1; Cyl 1; D11s287E; G1/S specific cyclin D1; G1/S-specific cyclin-D1; PRAD1; PRAD1 oncogene; U21B31	Human	E. coli
	The CCND1 protein is a regulatory component of the cyclin D1-CDK4 complex that coordinates phosphorylation and RB family inhibition to regulate the G(1)/S transition. This promotes the dissociation of E2F from the RB/E2F complex and promotes the transcription of E2F target genes critical for G(1) phase progression. CCND1 Protein, Human (His) is the recombinant human-derived CCND1 protein, expressed by E. coli , with N-6*His labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-17363S1

Dimethyl fumarate-d2

Dimethyl fumarate-d₂ is the deuterium labeled Dimethyl fumarate . Dimethyl fumarate (DMF) is an orally active and brain-penetrant Nrf2 activator and induces upregulation of antioxidant gene expression. Dimethyl fumarate induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway, and also induces cell autophagy. Dimethyl fumarate can be used for multiple sclerosis research .

HY-128454S

Dimethyl trisulfide-d6
Dimethyl trisulfide-d6 is deuterium labeled Dimethyl trisulfide (HY-128454). Dimethyl trisulfide is a cyanide antidote .

HY-W015301S2

Dimethyl adipate-d8
Dimethyl adipate-d₈ (Hexanedioic acid dimethyl ester-d₈) is the deuterium labeled Dimethyl adipate (HY-W015301). Dimethyl adipate is an aliphatic dicarboxylate compound. Dimethyl adipate is mainly used as a plasticizer and an intermediate in organic synthesis.

HY-Y1314S

Dimethyl sulfone-d6
Dimethyl sulfone-d₆ is the deuterium labeled Dimethyl sulfone. Dimethyl sulfone is an endogenous metabolite.

HY-B2062S

*Chlorthal-dimethyl-d6*
Chlorthal-dimethyl-d₆ is the deuterium labeled Chlorthal-dimethyl .

HY-W015301S1

Dimethyl adipate-d4-1
Dimethyl adipate-d₄-1 (Hexanedioic acid dimethyl ester-d₄-1) is the deuterium labeled Dimethyl adipate (HY-W015301). Dimethyl adipate is an aliphatic dicarboxylate compound. Dimethyl adipate is mainly used as a plasticizer and an intermediate in organic synthesis.

HY-W015301S

Dimethyl adipate-d4
Dimethyl adipate-d₄ (Hexanedioic acid dimethyl ester-d₄) is the deuterium labeled Dimethyl adipate (HY-W015301). Dimethyl adipate is an aliphatic dicarboxylate compound. Dimethyl adipate is mainly used as a plasticizer and an intermediate in organic synthesis.

HY-W001472S

Dimethyl pimelate-d4
Dimethyl pimelate-d₄ is the deuterium labeled Dimethyl pimelate .

HY-Y0808S

Dimethyl succinate-d4
Dimethyl succinate-d₄ is the deuterium labeled Dimethyl succinate .

HY-Y0383S

Dimethyl terephthalate-d4
Dimethyl terephthalate-d₄ is the deuterium labeled Dimethyl terephthalate. Dimethyl terephthalate is a low toxicity, low volatility industrial chemical widely used in the production of polyester fibers and films .

Host:	Mouse (11) Rabbit (10)
Reactivity:	Human (20) Rat (12) Mouse (15) Monkey (1)
Application:	IHC-P (13) ICC/IF (10) mIHC (1) IF-Tissue (2) IP (4) WB (13) ChIP (2) FC (8) Dot Blot (2) ELISA (8)
Isotype:	IgG (11) IgG1 (10)
Conjugation:	Non-conjugated (21) Biotin (1)
Clonality:	Polyclonal (1) polyclonal (1) Monoclonal (9) Recombinant (3)
Modification:	Methylated (4) Unmodified (10)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P85447

	PA28γ Antibody (YA5139) PSME3; Proteasome activator complex subunit 3; 11s regulator complex subunit gamma; REG-gamma; Activator of multicatalytic protease subunit 3; Ki nuclear autoantigen; Proteasome activator 28 subunit gamma; PA28g; PA28gamma	WB, ICC/IF, IP, ELISA, IF-Tissue	Human, Mouse, Rat
	PA28γ Antibody (YA5139) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to PA28γ.

HY-P87017

	PSME2 Antibody (YA6710) 11s regulator complex beta subunit antibody; 11s regulator complex subunit beta antibody; Activator of multicatalytic protease subunit 2 antibody; Cell migration inducing protein 22 antibody; MCP activator 31 kD subunit antibody; PA28 beta antibody; PA28b antibody; PA28beta antibody; Proteasome (prosome macropain) activator subunit 2 (PA28 beta) antibody; Proteasome (prosome macropain) activator subunit 2 antibody; 11s regulator complex beta subunit antibody; 11s regulator complex subunit beta antibody; Activator of multicatalytic protease subunit 2 antibody; Cell migration inducing protein 22 antibody; MCP activator 31 kD subunit antibody; PA28 beta antibody; PA28b antibody; PA28beta antibody; Proteasome (prosome macropain) activator subunit 2 (PA28 beta) antibody; Proteasome (prosome macropain) activator subunit 2 antibody; Proteasome activator 28 beta antibody; Proteasome activator 28 subunit beta antibody; Proteasome activator complex subunit 2 antibody; Proteasome activator hPA28 subunit beta antibody; Proteasome activator subunit 2 antibody; PSME 2 antibody; PSME2 antibody; PSME2_HUMAN antibody; REG beta antibody; REG-beta antibody; REGbeta antibody;	WB, ICC/IF, IHC-P, FC	Human, Mouse, Rat
	PSME2 Antibody (YA6710) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PSME2.

HY-P84219

	ACRV1 Antibody (YA3916) ACRV1,SP-10; SPACA2; D11s4365	IHC-P, FC, ELISA	Human
	ACRV1 Antibody (YA3916) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ACRV1.

HY-P89089

	SF1 Antibody (YA8773) BBP; D11s636; MBBP; ZCCHC25; ZFM1; ZNF162	IHC-P	Human
	SF1 Antibody (YA8773) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SF1.

HY-P84219A

	ACRV1 Antibody (YA3916)(PBS only) ACRV1,SP-10; SPACA2; D11s4365	IHC-P, FC, ELISA	Human
	ACRV1 Antibody (YA3916) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ACRV1.

HY-P89089A

	SF1 Antibody (YA8773)(PBS only) BBP; D11s636; MBBP; ZCCHC25; ZFM1; ZNF162	IHC-P	Human
	SF1 Antibody (YA8773) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SF1.

HY-P811003

	IL-31RA Antibody CRL3, GPL, UNQ6368/PRO21073/PRO21384, IL31rA, Interleukin-31 receptor subunit alpha, IL-31 receptor subunit alpha, IL-31r subunit alpha, IL-31r-alpha, IL-31rA, Cytokine receptor-like 3, GLM-R, Gp130-like monocyte receptor, ZcytoR17, hGLM-R, Gp130-like receptor	WB, ICC/IF	Human, Mouse, Rat
	IL-31RA Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to IL-31RA.

HY-P84204

	Cyclin D1/CCND1 Antibody (YA3901) BCL1; PRAD1; U21B31; D11s287E	WB, IHC-P, FC, ELISA	Human, Mouse
	Cyclin D1/CCND1 Antibody (YA3901) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Cyclin D1/CCND1.

HY-P82347

	Stromal Interaction Molecule 1 Antibody (YA2092) GOK; TAM; TAM1; IMD10; STRMK; D11s4896E	WB	Human, Mouse, Rat
	Stromal Interaction Molecule 1 Antibody (YA2092) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Stromal Interaction Molecule 1.

HY-P84203

	Cyclin D1/CCND1 Antibody (YA3900) BCL1; PRAD1; U21B31; D11s287E	IHC-P, ICC/IF, FC, ELISA	Human
	Cyclin D1/CCND1 Antibody (YA3900) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Cyclin D1/CCND1.

HY-P82347A

	Stromal Interaction Molecule 1 Antibody (YA2092)(PBS only) GOK; TAM; TAM1; IMD10; STRMK; D11s4896E	WB	Human, Mouse, Rat
	Stromal Interaction Molecule 1 Antibody (YA2092) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Stromal Interaction Molecule 1.

HY-P84203A

	Cyclin D1/CCND1 Antibody (YA3900)(PBS only) BCL1; PRAD1; U21B31; D11s287E	IHC-P, ICC/IF, FC, ELISA	Human
	Cyclin D1/CCND1 Antibody (YA3900) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Cyclin D1/CCND1.

HY-P84204A

	Cyclin D1/CCND1 Antibody (YA3901)(PBS only) BCL1; PRAD1; U21B31; D11s287E	WB, IHC-P, FC, ELISA	Human, Mouse
	Cyclin D1/CCND1 Antibody (YA3901) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Cyclin D1/CCND1.

HY-P80633

	Cyclin D1/CCND1 Antibody CCND1; BCL1; D11s287E; PRAD1; U21B31; Cyclin D1	WB, IHC-P, IP	Human, Mouse, Rat
	Cyclin D1/CCND1 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Cyclin D1/CCND1.

HY-P810523

	S100A11/ S100 alpha 11 Antibody Calgizzarin, MLN 70, MLN70, Protein S100 A11, Protein S100 C	IHC-P, ELISA, IF-Tissue	Human, Mouse, Rat
	S100A11/ S100 alpha 11 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to S100A11.

HY-P810560

	DiMethyl-Histone H3 (Lys4) Antibody H3K27me3; H3 histone; HIST1H3A; Histone cluster 1; H3a	WB, ICC/IF, IHC-P, FC, Dot Blot	Human, Mouse, Rat
	DiMethyl-Histone H3 (Lys4) Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to DiMethyl-Histone H3 (Lys4).

HY-P80643

	DiMethyl-Histone H3 Antibody (YA783) H3K27me2; H3 histone; HIST1H3A; Histone cluster 1; H3a	WB, ICC/IF, IP	Human, Mouse, Rat
	DiMethyl-Histone H3 Antibody (YA783) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DiMethyl-Histone H3.

HY-P810565

	DiMethyl-Histone H3 (Lys27) Antibody (YA9831) H3K27me3; H3 histone; HIST1H3A; Histone cluster 1; H3a	WB, ICC/IF, ChIP	Human, Mouse, Rat
	DiMethyl-Histone H3 (Lys27) Antibody (YA9831) is a Rabbit-derived and non-conjugated IgG Recombinant, Monoclonal antibody, targeting to DiMethyl-Histone H3 (Lys27).

HY-P80643A

	DiMethyl-Histone H3 Antibody (YA783)(PBS only) H3K27me2; H3 histone; HIST1H3A; Histone cluster 1; H3a	WB, ICC/IF, IP	Human, Mouse, Rat
	DiMethyl-Histone H3 Antibody (YA783) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DiMethyl-Histone H3.

HY-P810570

	DiMethyl-Histone H3 (Lys4) Antibody (YA9836) H3K27me3; H3 histone; HIST1H3A; Histone cluster 1; H3a	WB, ICC/IF, ChIP, Dot Blot, IHC-P	Human, Mouse, Rat, Monkey
	DiMethyl-Histone H3 (Lys4) Antibody (YA9836) is a Rabbit-derived and non-conjugated IgG Recombinant, Monoclonal antibody, targeting to DiMethyl-Histone H3 (Lys4).

HY-P86919

	PAX6 Antibody(YA6612) AN 2 antibody; AN antibody; AN2 antibody; Aniridia type II protein antibody; D11s812E antibody; FVH1 antibody; KIAA0552 antibody; Leucine zipper putative tumor suppressor 3 antibody; LZTS3 antibody; MGC17209 antibody; AN 2 antibody; AN antibody; AN2 antibody; Aniridia type II protein antibody; D11s812E antibody; FVH1 antibody; KIAA0552 antibody; Leucine zipper putative tumor suppressor 3 antibody; LZTS3 antibody; MGC17209 antibody; MGDA antibody; Oculorhombin antibody; Paired box 6 antibody; Paired box gene 6 (aniridia keratitis) antibody; Paired Box Gene 6 antibody; Paired box homeotic gene 6 antibody; Paired box protein Pax-6 antibody; Paired box protein Pax6 antibody; PAX 6 antibody; PAX6 antibody; PAX6_HUMAN antibody; ProSAP-interacting protein 1 antibody; PROSAPIP1 antibody; Sey antibody; WAGR antibody;	mIHC	Mouse
	PAX6 Antibody(YA6612) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PAX6.

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HY-134524

*Isosorbide dimethyl* ether** dimethyl isosorbide; O,O-dimethylisosorbide		Solvents
Isosorbide dimethyl ether is a green solvent. Isosorbide dimethyl ether can be used to prepare sustainable ultrafiltration and microfiltration membranes .

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11s-31r-16-36-37-trimethoxy-12-32-dimethyl-11-12-13-14-31-32-33-34-oc

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