2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies
  5. SF1 Antibody (YA8773)(PBS only)

SF1 Antibody (YA8773)(PBS only)

Cat. No.: HY-P89089A
User Guide for Antibodies Technical Support

SF1 Antibody (YA8773) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SF1.

For research use only. We do not sell to patients.

Size Stock
50 μL   Get quote  
100 μL   Get quote  

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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Documentation

Description

SF1 Antibody (YA8773) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SF1.
Host

Mouse
Species Reactivity
Human
SwissProt ID
Immunogen

Human recombinant protein fragment corresponding to amino acids 1-276 of human SF1 produced in E.coli.
Application &
Dilution Ratio
Application Dilution Ratio
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:150-500
Purity Affinity purified Conjugation Non-conjugated
Isotype IgG1  
Appearance

Liquid
Formulation

Supplied in PBS, pH 7.4.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Background
Function：Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor
Subcellular Localization：Nucleus
Expression：
Tissue_Specificity: Detected in lung, ovary, adrenal gland, colon, kidney, muscle, pancreas, thyroid, placenta, brain, liver and heart
Isoforms & Post-Translational Modification：Q15637 has 7 isomers: Q15637-1: 68330 Da (predicted); Q15637-2: 68633 Da (predicted); Q15637-3: 67277 Da (predicted); Q15637-4: 59712 Da (predicted); Q15637-5: 71752 Da (predicted); Q15637-6: 61889 Da (predicted); Q15637-7: 65371 Da (predicted).
Phosphorylation on Ser-20 interferes with U2AF2 binding and spliceosome assembly
Subunit：Binds U2AF2
Synonyms
BBP; D11S636; MBBP; ZCCHC25; ZFM1; ZNF162
Documentation
User Guide for Antibodies (1077 KB)

SF1 Antibody (YA8773)(PBS only) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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SF1 Antibody (YA8773)(PBS only)
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