2,5-Dimethyl-3(2H)-furanone
Based on 1 Customer Validation
2,5-Dimethyl-3(2H)-furanone (2,5-Dimethyl-2,3-dihydrofuran-3-one) is a type of furanone-based fragrance compound. 2,5-Dimethyl-3(2H)-furanone has no ability to damage DNA and no genetic toxicity.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 14400-67-0
- Formula: C6H8O2
- Molecular Weight:112.13
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Storage:
4°C, protect from light
* The compound is unstable in solutions, freshly prepared is recommended.
Biological Activity
Chemical Information
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CAS No. 14400-67-0
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Appearance Liquid (Density: 1.06 g/cm3)
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Molecular Weight 112.13
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Formula C6H8O2
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Color Colorless to light yellow
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SMILES
O=C1C(C)OC(C)=C1
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Synonyms
2,5-Dimethyl-2,3-dihydrofuran-3-one
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* The compound is unstable in solutions, freshly prepared is recommended.
Solvent & Solubility
DMSO : 100 mg/mL (891.82 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (22.30 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * The compound is unstable in solutions, freshly prepared is recommended.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (274 KB)
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SDS (604 KB)
- English - EN (604 KB)
- Français - FR (604 KB)
- Deutsch - DE (604 KB)
- Norwegian - NO (604 KB)
- Español - ES (604 KB)
- Swedish - SV (604 KB)
- Italian - IT (604 KB)
- Korean - KR (604 KB)
- Portuguese - PT (604 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 8.9182 mL | 44.5911 mL | 89.1822 mL | 222.9555 mL |
| 5 mM | 1.7836 mL | 8.9182 mL | 17.8364 mL | 44.5911 mL | |
| 10 mM | 0.8918 mL | 4.4591 mL | 8.9182 mL | 22.2956 mL | |
| 15 mM | 0.5945 mL | 2.9727 mL | 5.9455 mL | 14.8637 mL | |
| 20 mM | 0.4459 mL | 2.2296 mL | 4.4591 mL | 11.1478 mL | |
| 25 mM | 0.3567 mL | 1.7836 mL | 3.5673 mL | 8.9182 mL | |
| 30 mM | 0.2973 mL | 1.4864 mL | 2.9727 mL | 7.4319 mL | |
| 40 mM | 0.2230 mL | 1.1148 mL | 2.2296 mL | 5.5739 mL | |
| 50 mM | 0.1784 mL | 0.8918 mL | 1.7836 mL | 4.4591 mL | |
| 60 mM | 0.1486 mL | 0.7432 mL | 1.4864 mL | 3.7159 mL | |
| 80 mM | 0.1115 mL | 0.5574 mL | 1.1148 mL | 2.7869 mL | |
| 100 mM | 0.0892 mL | 0.4459 mL | 0.8918 mL | 2.2296 mL |