1. Metabolic Enzyme/Protease
  2. ATP Citrate Lyase
    Acyltransferase
  3. 2-Furoic acid

2-Furoic acid (Synonyms: Furan-2-carboxylic acid)

Cat. No.: HY-W012946 Purity: >98.0%
Handling Instructions

2-Furoic acid (Furan-2-carboxylic acid) is an organic compound produced through furfural oxidation. 2-Furoic acid exhibits hypolipidemic effet, lowers both serum cholesterol and serum triglyceride levels in rats.

For research use only. We do not sell to patients.

2-Furoic acid Chemical Structure

2-Furoic acid Chemical Structure

CAS No. : 88-14-2

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Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
100 mg USD 50 In-stock
Estimated Time of Arrival: December 31
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Description

2-Furoic acid (Furan-2-carboxylic acid) is an organic compound produced through furfural oxidation[1]. 2-Furoic acid exhibits hypolipidemic effet, lowers both serum cholesterol and serum triglyceride levels in rats[2].

In Vivo

2-Furoic acid significantly reduces serum cholesterol and serum triglyceride levels[2].
2-Furoic acid also lowers the liver and small intestine ATP dependent citrate lyase, acetyl CoA synthetase, acyl CoA cholesterol acyl transferase, sn-glycerol 3-phosphate acyl transferase, phosphatidylate phosphohydrolase and heparin induced lipoprotein lipase activities[2].
2-Furoic acid shows the LD50 of 250 mg/kg i.p. in the acute toxicity studies in mice[2].

Molecular Weight

112.08

Formula

C₅H₄O₃

CAS No.

88-14-2

SMILES

O=C(C1=CC=CO1)O

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (892.22 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 8.9222 mL 44.6110 mL 89.2220 mL
5 mM 1.7844 mL 8.9222 mL 17.8444 mL
10 mM 0.8922 mL 4.4611 mL 8.9222 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (22.31 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (22.31 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (22.31 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: >98.0%

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2-Furoic acid
Cat. No.:
HY-W012946
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