IL-31R alpha Protein, Human (HEK293, His)

IL-31R alpha Proteinas associates with IgM heavy and light chains, aiding IgM assembly and secretion. It may act as a molecular chaperone or oxidoreductase, showing low oxidoreductase activity. Isoform 2 might regulate apoptosis. IL-31R alpha contributes to peripheral B-cell function diversification by modulating Ca(2+) stores, antibody secretion, and integrin activation. Additionally, it acts as a hormone-regulated adipokine/inflammatory cytokine, involved in chronic inflammation, impacting cellular expansion and insulin response in adipocytes, potentially contributing to insulin resistance onset. IL-31R alpha Protein, Human (HEK293, His) is the recombinant human-derived IL-31R alpha protein, expressed by HEK293, with C-His labeled tag. The total length of IL-31R alpha Protein, Human (HEK293, His) is 516 a.a., with molecular weight of ~58.2 kDa.

MZB1/PERP1 associates with immunoglobulin M (IgM) heavy and light chains, facilitating IgM assembly and secretion. It may function as a molecular chaperone or oxidoreductase, as it exhibits a low level of oxidoreductase activity. Additionally, isoform 2 may play a role in apoptosis regulation. MZB1/PERP1 contributes to the diversification of peripheral B-cell functions by modulating Ca(2+) stores, antibody secretion, and integrin activation. Furthermore, it acts as a hormone-regulated adipokine/pro-inflammatory cytokine implicated in chronic inflammation, affecting cellular expansion and attenuating insulin response in adipocytes, potentially playing a role in the onset of insulin resistance.

Human

HEK293

C-His

Q8NI17 (M1-S516)

133396  [NCBI]

Approximately 58.2 kDa

Greater than 85% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.