PAX6 Antibody(YA6612)

Cat. No.: HY-P86919: Data Sheet User Guide for Antibodies
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PAX6 Antibody(YA6612) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PAX6.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

PAX6 Antibody(YA6612) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PAX6.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Molecular Weight

Predicted band size: 47 kDa

Species Reactivity

Mouse

SwissProt ID

P26367

Gene ID

5080 [NCBI]

Immunogen

Synthetic peptide within Human PAX6 aa 373-422 / 422.

Application &
Dilution Ratio

Application	Dilution Ratio
mIHC mIHC: Multiplex Immunohistochemical	1:100

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Acts as a transcriptional repressor of NFATC1-mediated gene expression (By similarity)

Subcellular Localization：Nucleus,Nucleus,Nucleus

Expression：
Tissue_Specificity: Expressed in lymphoblasts|Weakly expressed in lymphoblasts

Isoforms & Post-Translational Modification：P26367 has three isomers: P26367-1: 46683 Da (predicted); P26367-2: 48218 Da (predicted); P26367-3: Da (predicted).
Ubiquitinated by TRIM11, leading to ubiquitination and proteasomal degradation

Subunit：Interacts with MAF and MAFB (By similarity)

Synonyms

AN 2 antibody; AN antibody; AN2 antibody; Aniridia type II protein antibody; D11S812E antibody; FVH1 antibody; KIAA0552 antibody; Leucine zipper putative tumor suppressor 3 antibody; LZTS3 antibody; MGC17209 antibody; AN 2 antibody; AN antibody; AN2 antibody; Aniridia type II protein antibody; D11S812E antibody; FVH1 antibody; KIAA0552 antibody; Leucine zipper putative tumor suppressor 3 antibody; LZTS3 antibody; MGC17209 antibody; MGDA antibody; Oculorhombin antibody; Paired box 6 antibody; Paired box gene 6 (aniridia keratitis) antibody; Paired Box Gene 6 antibody; Paired box homeotic gene 6 antibody; Paired box protein Pax-6 antibody; Paired box protein Pax6 antibody; PAX 6 antibody; PAX6 antibody; PAX6_HUMAN antibody; ProSAP-interacting protein 1 antibody; PROSAPIP1 antibody; Sey antibody; WAGR antibody;

Documentation

User Guide for Antibodies (1077 KB)