PAX6 Antibody(YA6612)
(Synonyms: AN 2 antibody; AN antibody; AN2 antibody; Aniridia type II protein antibody; D11S812E antibody; FVH1 antibody; KIAA0552 antibody; Leucine zipper putative tumor suppressor 3 antibody; LZTS3 antibody; MGC17209 antibody; AN 2 antibody; AN antibody; AN2 antibody; Aniridia type II protein antibody; D11S812E antibody; FVH1 antibody; KIAA0552 antibody; Leucine zipper putative tumor suppressor 3 antibody; LZTS3 antibody; MGC17209 antibody; MGDA antibody; Oculorhombin antibody; Paired box 6 antibody; Paired box gene 6 (aniridia keratitis) antibody; Paired Box Gene 6 antibody; Paired box homeotic gene 6 antibody; Paired box protein Pax-6 antibody; Paired box protein Pax6 antibody; PAX 6 antibody; PAX6 antibody; PAX6_HUMAN antibody; ProSAP-interacting protein 1 antibody; PROSAPIP1 antibody; Sey antibody; WAGR antibody; )PAX6 Antibody(YA6612) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PAX6.
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
mIHC
-
Reactivity :
Mouse
-
Formulation:
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
mIHC
mIHC: Multiplex Immunohistochemical
|
|---|---|
| Dilution Ratio | 1:100 |
Product Details
PAX6 Antibody(YA6612) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PAX6.
-
Host Rabbit
-
Clonality Recombinant,Monoclonal
-
Species ReactivityMouse
-
Calculated Molecular Weight Predicted band size: 47 kDa
Synthetic peptide within Human PAX6 aa 373-422 / 422.
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
-
Appearance
Liquid
-
Formulation
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
PAX6 transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells. Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains. Acts as a transcriptional repressor of NFATC1-mediated gene expression
-
Subcellular Localization
Nucleus,Nucleus,Nucleus
-
Expression
Tissue_Specificity: Expressed in lymphoblasts|Weakly expressed in lymphoblasts -
Isoforms & Post-Translational Modification
P26367 has three isomers: P26367-1: 46683 Da (predicted); P26367-2: 48218 Da (predicted); P26367-3: Da (predicted).
Ubiquitinated by TRIM11, leading to ubiquitination and proteasomal degradation -
Subunit
Interacts with MAF and MAFB (By similarity)
-
SwissProt ID
-
Synonyms
AN 2 antibody; AN antibody; AN2 antibody; Aniridia type II protein antibody; D11S812E antibody; FVH1 antibody; KIAA0552 antibody; Leucine zipper putative tumor suppressor 3 antibody; LZTS3 antibody; MGC17209 antibody; AN 2 antibody; AN antibody; AN2 antibody; Aniridia type II protein antibody; D11S812E antibody; FVH1 antibody; KIAA0552 antibody; Leucine zipper putative tumor suppressor 3 antibody; LZTS3 antibody; MGC17209 antibody; MGDA antibody; Oculorhombin antibody; Paired box 6 antibody; Paired box gene 6 (aniridia keratitis) antibody; Paired Box Gene 6 antibody; Paired box homeotic gene 6 antibody; Paired box protein Pax-6 antibody; Paired box protein Pax6 antibody; PAX 6 antibody; PAX6 antibody; PAX6_HUMAN antibody; ProSAP-interacting protein 1 antibody; PROSAPIP1 antibody; Sey antibody; WAGR antibody;
Documentation
Powered by Bioz
