SF1 Antibody (YA8773)
(Synonyms: BBP; D11S636; MBBP; ZCCHC25; ZFM1; ZNF162)SF1 Antibody (YA8773) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SF1.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P
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Reactivity :
Human
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:150-500 |
Product Details
SF1 Antibody (YA8773) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SF1.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
Human recombinant protein fragment corresponding to amino acids 1-276 of human SF1 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
SF1 is a Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor
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Subcellular Localization
Nucleus
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Expression
Tissue_Specificity: Detected in lung, ovary, adrenal gland, colon, kidney, muscle, pancreas, thyroid, placenta, brain, liver and heart -
Isoforms & Post-Translational Modification
Q15637 has 7 isomers: Q15637-1: 68330 Da (predicted); Q15637-2: 68633 Da (predicted); Q15637-3: 67277 Da (predicted); Q15637-4: 59712 Da (predicted); Q15637-5: 71752 Da (predicted); Q15637-6: 61889 Da (predicted); Q15637-7: 65371 Da (predicted).
Phosphorylation on Ser-20 interferes with U2AF2 binding and spliceosome assembly -
Subunit
Binds U2AF2
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SwissProt ID
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Synonyms
BBP; D11S636; MBBP; ZCCHC25; ZFM1; ZNF162
Documentation
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