cis-3,4',5-Trimethoxy-3'-hydroxystilbene
Based on 1 Customer Validation
cis-3,4',5-Trimethoxy-3'-hydroxystilbene is a stilbene. cis-3,4',5-Trimethoxy-3'-hydroxystilbene induces cytochrome c release to the cytoplasm. cis-3,4',5-Trimethoxy-3'-hydroxystilbene-induced apoptosis is associated with mitochondrial release of cytochrome c. cis-3,4',5-Trimethoxy-3'-hydroxystilbene also suppresses tubulin polymerization. cis-3,4',5-Trimethoxy-3'-hydroxystilbene can be used for leukemic research.
For research use only. We do not sell to patients.
- Purity: 99.59%
- CAS No.: 586410-08-4
- Formula: C17H18O4
- Molecular Weight:286.32
-
Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
-
Bioactive Compound Library Max
HY-L181
-
Bioactive Compound Library
HY-L001
-
Apoptosis Compound Library
HY-L003
-
Cell Cycle/DNA Damage Compound Library
HY-L004
-
Anti-Cancer Compound Library
HY-L025
-
Anti-Aging Compound Library
HY-L034
-
Cytoskeleton Compound Library
HY-L060
-
Anti-Lung Cancer Compound Library
HY-L075
-
Protein-protein Interaction Inhibitor Library
HY-L109
-
Cell Death Library
HY-L162
-
MCE Bioactive Compound Library
HY-L001V
-
Non-Alcoholic Fatty Liver Disease (NAFLD) Compound Library
HY-L199
-
High-Throughput Bioactive Compound Library
HY-L205
-
High-Efficiency Gene Editing Compound Library
HY-L244
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HL-60 | IC50 |
0.02 μM
Compound: 11b
|
In vitro inhibitory concentration against proliferation of HL60R cells along with 5 (uM) verapamil
In vitro inhibitory concentration against proliferation of HL60R cells along with 5 (uM) verapamil
|
[PMID: 12877593] |
| HL-60 | IC50 |
0.025 μM
Compound: 11b
|
In vitro inhibitory concentration against proliferation of HL60R cells
In vitro inhibitory concentration against proliferation of HL60R cells
|
[PMID: 12877593] |
| HL-60 | IC50 |
0.03 μM
Compound: 11b
|
In vitro inhibitory concentration against proliferation of HL60 cells
In vitro inhibitory concentration against proliferation of HL60 cells
|
[PMID: 12877593] |
| HL-60 | IC50 |
30 nM
Compound: 1b
|
Induction of apoptosis in human HL60 cells by flow cytometry
Induction of apoptosis in human HL60 cells by flow cytometry
|
[PMID: 19117761] |
| HL-60 | IC50 |
30 nM
Compound: cis-3,5,4'-trimethoxy-3'-hydroxystilbene
|
Induction of apoptosis in Homo sapiens (human) HL60 cells
Induction of apoptosis in Homo sapiens (human) HL60 cells
|
10.1007/s00044-010-9450-y |
| SNU-423 | IC50 |
15 nM
Compound: 1b
|
Cytotoxicity against human SNU423 cells after 48 hrs by alamar blue assay
Cytotoxicity against human SNU423 cells after 48 hrs by alamar blue assay
|
[PMID: 19117761] |
cis-3,4',5-Trimethoxy-3'-hydroxystilbene (10-500 nM) eliminates the colony-forming ability of HL60 cells[1].
cis-3,4',5-Trimethoxy-3'-hydroxystilbene (10-500 nM) induces dose-dependent apoptosis in HL60 cells but does not affect bone marrow progenitor cells[1].
cis-3,4',5-Trimethoxy-3'-hydroxystilbene (0-100 μM) inhibits tubulin polymerization in a dose-dependent manner[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 586410-08-4
-
Appearance Oil
-
Molecular Weight 286.32
-
Formula C17H18O4
-
Color Colorless to light yellow
-
SMILES
OC(C=C1/C=C\C2=CC(OC)=CC(OC)=C2)=C(C=C1)OC
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
-
Data Sheet (268 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
cis-3,4',5-Trimethoxy-3'-hydroxystilbene Related Classifications
HY-118452 Related Classifications
Powered by Bioz