Search Result

Isoforms Recommended:	TNFRSF16/NGF Receptor/CD271

Results for "

NGF

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (5) Acyltransferase (3) Adrenergic Receptor (5) Akt (4) Amyloid-β (1) Apoptosis (5) Autophagy (2) Biochemical Assay Reagents (1) CaMK (1) Dopamine Receptor (3) Drug Derivative (1) E1/E2/E3 Enzyme (2) Epigenetic Reader Domain (2) ERK (6) Histamine Receptor (7) Histone Acetyltransferase (1) Interleukin Related (6) Isotope-Labeled Compounds (2) JNK (5) Keap1-Nrf2 (2) Lipase (1) MAP3K (1) MAP4K (1) nAChR (2) Neurokinin Receptor (1) p62 (2) Phosphatase (1) PKA (1) PKC (4) Potassium Channel (1) PROTACs (1) Reactive Oxygen Species (ROS) (7) Reference Standards (8) Small Interfering RNA (siRNA) (3) TNF Receptor (9) Trk Receptor (33) VEGFR (5)
By Research Areas:	Cancer (17) Cardiovascular Disease (5) Endocrinology (7) Infection (2) Inflammation/Immunology (34) Metabolic Disease (3) Neurological Disease (45)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (2)

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Art. -Nr.	Produktname	Target	Forschungsgebiete	Chemical Structure

HY-N6732

K-252a 25+ Cited Publications SF2370; Antibiotic K 252a; Antibiotic SF 2370	Autophagy PKA PKC Trk Receptor CaMK	Infection Inflammation/Immunology
K-252a, a staurosporine analog, inhibits protein kinase, with IC₅₀ values of 470 nM, 140 nM, 270 nM, and 1.7 nM for PKC, PKA, Ca ²⁺/calmodulin-dependent kinase type II, and phosphorylase kinase, respectively . K-252a is a potent inhibitor (IC₅₀ of 3 nM) of the tyrosine protein kinase (TRK) activity of the NGF receptor gp140trk, the product of the trk protooncogene .

HY-108466

Ro 08-2750 4 Publications Verification	Apoptosis	Neurological Disease Cancer
Ro 08-2750 is a non-peptide and reversible nerve growth factor (NGF) inhibitor which binds to NGF, and with an IC₅₀ of ~ 1 μM. Ro 08-2750 inhibits NGF binding to p75 ^NTR selectively over TRKA . Ro 08-2750 is a selective _{MSI RNA-binding} activity inhibitor, with an IC₅₀ of 2.7 μM .

HY-P99221

Tanezumab RN-624; PF 4383119	Trk Receptor	Neurological Disease Inflammation/Immunology Cancer
Tanezumab (RN-624) is a humanized anti-NGF mAb with high affinity and specificity. Tanezumab blocks *NGF* binding to its receptors, p75 and TrkA, in the peripheral nervous system. Tanezumab can be used in studies of acute and chronic pain such as osteoarthritis, knee and neuralgia, as well as post-herpetic neuralgia .

HY-P99297

Bedinvetmab ZTS-00508841	Trk Receptor	Inflammation/Immunology
Bedinvetmab (ZTS-00508841) is a canine monoclonal antibody (mAb) targeting nerve growth factor (NGF). Bedinvetmab inhibits NGF interaction with tropomyosin receptor kinase A (trkA) and p75 neurotrophin receptor (p75NTR) receptors. Bedinvetmab can be used for the research of osteoarthritis pain in dogs .

HY-18314

GW 441756 5+ Cited Publications	Trk Receptor Apoptosis	Neurological Disease Cancer
GW 441756 is a potent and specific nerve growth factor (NGF) receptor tyrosine kinases A (TrkA) inhibitor (IC₅₀=2 nM), which eliminates the BmK NSPK-induced neurite outgrowth .

HY-133968

24-Methylenecholesterol 2 Publications Verification Ostreasterol	Acyltransferase Reactive Oxygen Species (ROS)	Inflammation/Immunology
24-Methylenecholesterol (Ostreasterol) is a regulator targeting acyl-CoA cholesterol acyltransferase (ACAT) with anti-aging and neuroprotective effects. 24-Methylenecholesterol mimics the effects of nerve growth factor (NGF), can extend yeast lifespan through an anti-oxidative stress mechanism, and exhibits neuroprotective activity in PC12 cells. 24-Methylenecholesterol can reduce intracellular reactive oxygen species (ROS) and malondialdehyde (MDA) levels, activate anti-oxidative stress pathways (such as UTH1, SOD-related genes), and promote synaptic growth .

HY-N6838

1,1,1,1-Kestohexaose 1,1,1,1-Kestohexose	Others	Others
1,1,1,1-Kestohexaose (1,1,1,1-Kestohexose) is an insulin-type fructooligosaccharide hexasaccharide. 1,1,1,1-Kestohexaose exhibits neuroprotective and anti-depressant-like activities. 1,1,1,1-Kestohexaose can alleviate Corticosteron (HY-B1618)-induced decrease in cell viability and NGF expression in vitro .

HY-P99677

Izenivetmab ZTS-00075623	Trk Receptor	Neurological Disease Inflammation/Immunology
Izenivetmab (ZTS-00075623) is an anti-NGFB IgG2κ monoclonal antibody. Izenivetmab shows anti-inflammatory and analgesic effects by targeting anti-nerve growth factor (NGF). Izenivetmab can be used for the research of osteoarthritis .

HY-A0015

Bepotastine besilate 1 Publications Verification	Histamine Receptor	Inflammation/Immunology Endocrinology
Bepotastine besilate is a selective and orally active second-generation histamine H1 receptor antagonist, can suppress the expression of nerve growth factor (NGF). Bepotastine besilate has the potential for allergic rhinitis, allergic conjunctivitis and urticaria/pruritus research .

HY-P99627

Frunevetmab NV-02; PG110; ABT-110	Trk Receptor	Inflammation/Immunology
Frunevetmab (NV-02) is a felinized anti-nerve growth factor (NGF) monoclonal antibody with a K_d of 20 pM. Frunevetmab can effectively decrease osteoarthritis (OA) pain in cats .

HY-17622

Tavilermide 2 Publications Verification MIM-D3	Trk Receptor	Inflammation/Immunology
Tavilermide is a selective, partial agonist of TrkA, or a nerve growth factor (NGF) mimetic.

HY-N4285

Negletein 5,6-Dihydroxy-7-methoxyflavone	TNF Receptor Interleukin Related Reactive Oxygen Species (ROS) Keap1-Nrf2 Amyloid-β	Infection Neurological Disease Inflammation/Immunology Cancer
Negletein (5,6-Dihydroxy-7-methoxyflavone) is a flavone found in Scutellaria. Negletein shows anti-inflammatory activity via inhibiting TNF-α and IL-1β with IC₅₀ values of 16.4 and 6.4 μM, respectively. Negletein can activate Nrf2 and inhibit ROS production. Negletein can enhance the neuroprotective effect of nerve growth factor. Negletein can inhibit amyloid beta-peptide release and accumulation. Negletein can inhibit pathogens biofilms formation. Negletein can be used for the researches of cancer, infection, inflammation and neurological disease, such as colon cancer and Alzheimer's disease .

HY-14604

Xaliproden hydrochloride 1 Publications Verification SR57746A; SR57746 hydrochloride	5-HT Receptor Dopamine Receptor Trk Receptor PKC ERK Akt JNK	Neurological Disease Metabolic Disease
Xaliproden (SR57746) hydrochloride (SR57746A) is an orally active, highly selective 5-HT1A receptor agonist. Xaliproden hydrochloride activates pertussis toxin-sensitive G protein-coupled signaling cascades, as well as the PKC, ERK1/ERK2, Akt and p21 Ras/MEK-1 pathways. Xaliproden hydrochloride also downregulates the JNK/p66/c-Jun signaling pathway, induces phosphorylation of the shc adaptor protein, regulates extracellular dopamine and 5-HT levels, and induces [ ³⁵S]GTPγS labeling in rat brain structures rich in 5-HT1A receptors. Xaliproden hydrochloride exerts neurotrophic, neuroprotective, renoprotective, anti-inflammatory, anti-apoptotic, anti-fibrotic and analgesic effects. Xaliproden hydrochloride also enhances *NGF*-induced neurite outgrowth, promotes motor neuron survival, attenuates renal tubular injury and inhibits chemotherapy-induced mechanical allodynia, without activating or altering *NGF*-induced TrkA receptor activation. Xaliproden hydrochloride can be used in the research of motor neuron disease, diabetic nephropathy, chemotherapy-induced peripheral neuropathy, amyotrophic lateral sclerosis, Alzheimer's disease, acute tonic nociceptive pain, inflammatory pain, depression and anxiety .

HY-122616

PF-06273340	Trk Receptor	Neurological Disease
PF-06273340 is a peripherally restricted pan-Trk inhibitor with IC₅₀ values of 6, 4, 3 nM for TrkA, TrkB, and TrkC receptors. PF-06273340 binds in a DFG-out conformation, targeting less conserved kinase ligand binding domain regions outside the ATP binding pocket. PF-06273340 exhibits anti-hyperalgesic and analgesic effects. PF-06273340 can be used for the research of pain .

HY-P99195

Fasinumab REGN-475; SAR-164877	Trk Receptor	Inflammation/Immunology
Fasinumab (Anti-Human NGF) is a human IgG4 monoclonal antibody to nerve growth factor (NGF). Fasinumab can be used in acute sciatica and knee osteoarthritis (OA) studies .

HY-N0380

Nardosinone	Others	Neurological Disease
Nardosinone, isolated from Nardostachys chinensis, is the first enhancer of the neuritogenic action of dbcAMP and staurosporine. Nardosinone may become a useful pharmacological tool for studying the mechanism of action of not only nerve growth factor (NGF) but also both the neuritogenic substances .

HY-I0021

Bepotastine 1 Publications Verification	Histamine Receptor	Inflammation/Immunology Endocrinology
Bepotastine is a selective and orally active second-generation histamine H1 receptor antagonist, can suppress the expression of nerve growth factor (NGF). Bepotastine has the potential for allergic rhinitis, allergic conjunctivitis and urticaria/pruritus research .

HY-B0446

Naphazoline hydrochloride 1 Publications Verification Naphthazoline hydrochloride	Adrenergic Receptor TNF Receptor Interleukin Related VEGFR	Cardiovascular Disease Inflammation/Immunology Cancer
Naphazoline (Naphthazoline) hydrochloride is a potent α-adrenergic receptor agonist. Naphazoline hydrochloride reduces vascular hyperpermeability and promotes vasoconstriction. Naphazoline hydrochloride reduces the levels of inflammatory factors (TNF-α, IL-1β and IL-6), cytokines (IFN-γ and IL-4), IgE, GMCSF, and NGF. Naphazoline hydrochloride can be used for non-bacterial conjunctivitis research .

HY-111326

Naphazoline 1 Publications Verification Naphthazoline	Adrenergic Receptor TNF Receptor Interleukin Related VEGFR	Cardiovascular Disease Inflammation/Immunology Cancer
Naphazoline (Naphthazoline) is a potent α-adrenergic receptor agonist. Naphazoline reduces vascular hyperpermeability and promotes vasoconstriction. Naphazoline reduces the levels of inflammatory factors (TNF-α, IL-1β and IL-6), cytokines (IFN-γ and IL-4), IgE, GMCSF, and NGF. Naphazoline can be used for non-bacterial conjunctivitis research .

HY-120553

B-355252 1 Publications Verification	Apoptosis	Neurological Disease
B355252, a phenoxy thiophene sulfonamide small molecule, is a potent NGF receptor agonist. B355252 potentiates NGF-induced neurite outgrowth. B355252 protects ischemic neurons from neuronal loss by attenuating DNA damage, reducing ROS production and the LDH level, and preventing neuronal apoptosis. B355252 has anti-apoptotic effects in glutamate-induced excitotoxicity, as well as in a murine hippocampal cell line (HT22) model of Parkinson disease (PD) .

HY-110166

PD 90780 2 Publications Verification	Trk Receptor	Neurological Disease
PD 90780 is a non peptide antagonist of nerve growth factor (NGF). PD 90780 interacts with NGF, prevents NGF binds with p75 ^NTR. PD 90780 inhibits NGF-p75 ^NTR interaction with IC₅₀s of 23.1 and 1.8 μM in PC12 cells and PC12 ^nnr5 cells, respectively .

HY-111326A

Naphazoline nitrate 1 Publications Verification Naphthazoline nitrate	Adrenergic Receptor TNF Receptor Interleukin Related VEGFR	Cardiovascular Disease Inflammation/Immunology Cancer
Naphazoline (Naphthazoline) nitrate is an α-adrenergic receptor agonist. Naphazoline nitrate reduces vascular hyperpermeability and promotes vasoconstriction. Naphazoline nitrate reduces the levels of inflammatory factors (TNF-α, IL-1β and IL-6), cytokines (IFN-γ and IL-4), IgE, GMCSF, and NGF. Naphazoline nitrate can be used for non-bacterial conjunctivitis research .

HY-117517

NG-012	Trk Receptor	Cancer
NG-012, potentiator of nerve growth factor (NGF), were isolated from the culture broth of Penicillium verruculosum F-4542. NG-012 potentiates the neurite outgrowth induced by NGF in rat pheochromocytoma cell line (PC12) .

HY-NP144

Nerve Growth Factor 7S,murine submaxillary gland	Biochemical Assay Reagents	Neurological Disease
Nerve Growth Factor 7S, murine submaxillary gland is an α2β2γ2 complex in which the β-NGF dimer (the active neurotrophin) is associated with two α-NGF and two γ-NGF subunits .

HY-N12566

Erinacin B	Others	Neurological Disease
Erinacin B is a active product that can be extracts from the mycelia of Hericium erinaceum. Erinacin B shows potent stimulating activity of nerve growth factor (NGF)-synthesis .

HY-P5156

BDS-I	Potassium Channel	Neurological Disease
BDS-I known as blood depressing substance, is a marine toxin which can be extracted from Anemonia sulcata. BDS-I is a specific inhibitor of Potassium Channel, targeting to Kv3.4. BDS-I inhibits Aβ1-42-induced enhancement of KV3.4 activity, caspase-3 activation, and abnormal nuclear morphology of NGF-differentiated PC-12 cells. BDS-I reverts the Aβ peptide-induced cell death .

HY-P99825

Relfovetmab	TNF Receptor	Neurological Disease Inflammation/Immunology
Relfovetmab is an anti-NGF monoclonal antibody (mAb) .

HY-P99820

Ranevetmab NV-01	TNF Receptor	Inflammation/Immunology
Ranevetmab (NV-01) is a caninised anti-NGF monoclonal antibody (mAb). Ranevetmab can alleviate pain, and is used for the research of degenerative joint disease (DJD) pain .

HY-N3938

Gelsemiol	Others	Neurological Disease
Gelsemiol is the main active ingredient in Verbena littoralis H. B. K.. Gelsemiol enhanced nerve growth factor (NGF) -induced axonal elongation in PC12D cells .

HY-P991711

Povovetug	Trk Receptor	Neurological Disease Inflammation/Immunology
Povovetug is a humanized IgG1κ chimeric monoclonal antibody inhibitor targeting *NGF/bNGF*. Povovetug has a significant analgesic activity. Povovetug can be used for central neuroinflammation like chronic radicular pain research .

HY-N15385

Hericenone D	Lipase	Metabolic Disease
Hericenone D, an orally active pancreatic lipase inhibitor, can be found in Hericium erinaceus. Hericenone D reduces lipid absorption and stimulates nerve growth factor *NGF* gene expression. Hericenone D can be used for the research of menopausal obesity .

HY-P3709

TRAF6 peptide	p62 E1/E2/E3 Enzyme	Neurological Disease
TRAF6 peptide is a specific TRAF6-p62 inhibitor. TRAF6 peptide potently abrogates NGF-dependent TrkA ubiquitination. TRAF6 peptide has good research potential in neurological diseases such as alzheimer's disease (AD), parkinson's, ALS, head trauma, epilepsy and stroke .

HY-171450

VMD-928	Trk Receptor	Cancer
VMD-928 is an orally active, allosteric, irreversible and selective tropomyosin receptor kinase A (TrkA) inhibitor. VMD-928 blocks the downstream signaling pathways triggered by the binding of nerve growth factor (NGF) to TrkA, thereby inhibiting cell proliferation, invasion, and promoting cancer cell death. VMD-928 is promising for research of various cancers, including prostate cancer, thymic carcinoma, mesothelioma, squamous cell carcinoma of the head and neck, squamous cell carcinoma of the lung, ovarian cancer, hepatocellular carcinoma .

HY-P990474

*Anti-NGF/bNGF Antibody* AS2886401-00	Trk Receptor	Inflammation/Immunology
Anti-NGF/bNGF Antibody is a CHO-expressed humanized antibody that targets *NGF/bNGF. Anti-NGF/bNGF Antibody has a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 144.14 kDa. The isotype control for Anti-NGF*/bNGF Antibody can be referenced as Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P99200

Fulranumab	Trk Receptor	Neurological Disease
Fulranumab is a human IgG2 monoclonal antibody against nerve growth factor (NGF) and can be used for the research of pain .

HY-165616

NS 1231	Trk Receptor	Neurological Disease
NS 1231 is a neurotrophic-like compound with neuroprotective effect. NS 1231 can rescue nerve growth factor (NGF)-differentiated PC12 cells from death induced by withdrawal of trophic factors. NS 1231 can stimulate NGF-induced neurite outgrowth of undifferentiated PC12 cells. NS 1231 can be used for the research of neurological disease, such as stroke .

HY-P991622

MNAC13	Trk Receptor	Neurological Disease Inflammation/Immunology
MNAC13 is a kind of mouse IgG1 chimeric antibody, targeting to human TrkA. MNAC13 inhibits the NGF dependent signaling pathway by specifically binding to TrkA receptors. MNAC13 has good analgesic effect and long-lasting efficacy. MNAC13 can be used for researches on inflammatory and chronic pain .

HY-11055

KP 544	Histone Acetyltransferase	Neurological Disease
KP 544 is a potent neurotrophic protein enhancer that amplifies nerve growth factor (NGF)-induced neurite outgrowth of PC12 cells and SH-SY5Y neuroblastoma cells. KP544 also enhances choline acetyltransferase activity. KP 544 selectively interact in the differentiation pathway downstream of MAPK in a manner that amplifies nerve growth factor and cyclic AMP effects and is also neuroprotective .

HY-RS16265

Ngf Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Ngf Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ngf gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ngf Mouse Pre-designed siRNA Set A Ngf Mouse Pre-designed siRNA Set A

HY-P991324

MEDI-7352	Trk Receptor TNF Receptor	Inflammation/Immunology
MEDI-7352 is a human bispecific antibody (bsAb) targeting NGF/bNGF & TNF. MEDI-7352 can be used in osteoarthritis (OA) pain research .

HY-E70869

TRKA(NTRK1) Recombinant Human Active Protein Kinase	Trk Receptor	Neurological Disease
TRKA (also named NTRK1) is a potential new member of the tyrosine kinase gene family. TRKA is a receptor tyrosine kinase that is phosphorylated in response to NGF. A single transmembrane domain divides TRKA into an extracellular domain, important for NGF binding, and an intracellular tyrosine kinase domain, important for signal transduction. TRKA(NTRK1) Recombinant Human Active Protein Kinase is a recombinant TRKA(NTRK1) protein that can be used to study TRKA(NTRK1)-related functions .

HY-N3928

Garciniaxanthone E	Others	Neurological Disease
Garciniaxanthone E is a xanthone compound. Garciniaxanthone E significantly enhances cellular nerve growth factor (NGF)-mediated neurite outgrowth in PC12D cells. Garciniaxanthone E contributes to basic research and medicinal development in neurodegenerative diseases .

HY-P3709A

TRAF6 peptide TFA	p62 E1/E2/E3 Enzyme	Neurological Disease
TRAF6 peptide TFA is a specific TRAF6-p62 inhibitor. TRAF6 peptide TFA potently abrogates NGF-dependent TrkA ubiquitination. TRAF6 peptide TFA has good research potential in neurological diseases such as alzheimer's disease (AD), parkinson's, ALS, head trauma, epilepsy and stroke .

HY-124637

ALE-0540	Trk Receptor	Neurological Disease
ALE-0540, a nonpeptidic small molecule, is a nerve growth factor receptor antagonist. ALE-0540 inhibits the binding of NGF to tyrosine kinase (Trk) A or both p75 and TrkA with IC₅₀ values of 5.88 μM and 3.72 μM, respectively. ALE-0540 can be used to examine mechanisms leading to the development of agents for the study of pain .

HY-A0015A

(Rac)-Bepotastine besilate	Histamine Receptor	Inflammation/Immunology Endocrinology
(Rac)-Bepotastine (besilate) is the isomer of Bepotastine (besilate) (HY-A0015), and can be used as an experimental control. Bepotastine besilate is a selective and orally active second-generation histamine H1 receptor antagonist, can suppress the expression of nerve growth factor (NGF). Bepotastine besilate has the potential for allergic rhinitis, allergic conjunctivitis and urticaria/pruritus research .

HY-59201A

A-582941 dihydrochloride	ERK 5-HT Receptor Epigenetic Reader Domain nAChR	Neurological Disease Metabolic Disease
A-582941 dihydrochloride is a selective, orally active, blood-brain barrier-permeable α7 nAChR agonist, with K_i values of 10.8 nM and 17 nM in rat brain and human frontal cortex, respectively. A-582941 dihydrochloride exhibits agonistic activity at 5-HT3 receptors, with a K_i of 150 nM. A-582941 dihydrochloride triggers phosphorylation of ERK1/2 and CREB, inhibits GSK-3β via Ser-9 phosphorylation, increases acetylcholine release, induces the expression of Arc and c-Fos, activates brain regions associated with working memory and attention, and reduces cell death caused by nerve growth factor (NGF) deprivation. A-582941 dihydrochloride is applicable for the research of Alzheimer's disease and schizophrenia .

HY-RS09277

NGF Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
NGF Human Pre-designed siRNA Set A contains three designed siRNAs for NGF gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

NGF Human Pre-designed siRNA Set A NGF Human Pre-designed siRNA Set A

HY-RS22931

Ngf Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Ngf Rat Pre-designed siRNA Set A contains three designed siRNAs for Ngf gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ngf Rat Pre-designed siRNA Set A Ngf Rat Pre-designed siRNA Set A

HY-P991323

MEDI-1912	Trk Receptor Neurokinin Receptor	Inflammation/Immunology
MEDI-1912 is a human monoclonal antibody (mAb) targeting *NGF/bNGF. MEDI-1912 inhibits signaling through TrkA* and p75 receptors. MEDI-1912 can be used in chronic pain research .

HY-N15532

Phenylmethyl 6-O-α-L-arabinofuranosyl-β-D-glucopyranoside	Trk Receptor	Neurological Disease
Phenylmethyl 6-O-α-L-arabinofuranosyl-β-D-glucopyranoside (Compound 12) is a nerve growth factor (NGF) secretion promoter, which is found in plants of the genus Piper. Phenylmethyl 6-O-α-L-arabinofuranosyl-β-D-glucopyranoside is promising for research of neurodegenerative diseases (such as Parkinson's disease and Alzheimer's disease) and diabetic polyneuropathy .

Art. -Nr.	Produktname	Target	Research Area

HY-P5156

BDS-I	Potassium Channel	Neurological Disease
BDS-I known as blood depressing substance, is a marine toxin which can be extracted from Anemonia sulcata. BDS-I is a specific inhibitor of Potassium Channel, targeting to Kv3.4. BDS-I inhibits Aβ1-42-induced enhancement of KV3.4 activity, caspase-3 activation, and abnormal nuclear morphology of NGF-differentiated PC-12 cells. BDS-I reverts the Aβ peptide-induced cell death .

HY-P3709

TRAF6 peptide	p62 E1/E2/E3 Enzyme	Neurological Disease
TRAF6 peptide is a specific TRAF6-p62 inhibitor. TRAF6 peptide potently abrogates NGF-dependent TrkA ubiquitination. TRAF6 peptide has good research potential in neurological diseases such as alzheimer's disease (AD), parkinson's, ALS, head trauma, epilepsy and stroke .

HY-P3709A

TRAF6 peptide TFA	p62 E1/E2/E3 Enzyme	Neurological Disease
TRAF6 peptide TFA is a specific TRAF6-p62 inhibitor. TRAF6 peptide TFA potently abrogates NGF-dependent TrkA ubiquitination. TRAF6 peptide TFA has good research potential in neurological diseases such as alzheimer's disease (AD), parkinson's, ALS, head trauma, epilepsy and stroke .

HY-P10140

JNK-IN-15, Cell-Permeable	JNK	Cancer
JNK-IN-15, Cell-Permeable (JNK inhibitor III) is an inhibitor of JNK. JNK-IN-15, Cell-Permeable can used in study age-related neurodegenerative diseasev .

HY-P10141

JNK-IN-15, Cell-Permeable, Negative Control	JNK	Cancer
JNK-IN-15, Cell-Permeable, Negative Control is a negative control of JNK-IN-15, Cell-Permeable (HY-P10140). JNK-IN-15, Cell-Permeable is an inhibitor of JNK .

HY-P11480

*TrkA/NGF-IN-1*	Trk Receptor	Neurological Disease
TrkA/NGF-IN-1 (Peptide 19) is an inhibitor of protein-protein interactions between TrkA and *NGF* (IC₅₀: 21 nM for human TrkA in PathHunter assay). TrkA/NGF-IN-1 shows an analgesic effect in a rat incisional pain model .

Art. -Nr.	Produktname	Target	Research Area	Image

HY-P99221

Tanezumab RN-624; PF 4383119	Trk Receptor	Neurological Disease Inflammation/Immunology Cancer
Tanezumab (RN-624) is a humanized anti-NGF mAb with high affinity and specificity. Tanezumab blocks *NGF* binding to its receptors, p75 and TrkA, in the peripheral nervous system. Tanezumab can be used in studies of acute and chronic pain such as osteoarthritis, knee and neuralgia, as well as post-herpetic neuralgia .

HY-P99297

Bedinvetmab ZTS-00508841	Trk Receptor	Inflammation/Immunology
Bedinvetmab (ZTS-00508841) is a canine monoclonal antibody (mAb) targeting nerve growth factor (NGF). Bedinvetmab inhibits NGF interaction with tropomyosin receptor kinase A (trkA) and p75 neurotrophin receptor (p75NTR) receptors. Bedinvetmab can be used for the research of osteoarthritis pain in dogs .

HY-P99677

Izenivetmab ZTS-00075623	Trk Receptor	Neurological Disease Inflammation/Immunology
Izenivetmab (ZTS-00075623) is an anti-NGFB IgG2κ monoclonal antibody. Izenivetmab shows anti-inflammatory and analgesic effects by targeting anti-nerve growth factor (NGF). Izenivetmab can be used for the research of osteoarthritis .

HY-P99627

Frunevetmab NV-02; PG110; ABT-110	Trk Receptor	Inflammation/Immunology
Frunevetmab (NV-02) is a felinized anti-nerve growth factor (NGF) monoclonal antibody with a K_d of 20 pM. Frunevetmab can effectively decrease osteoarthritis (OA) pain in cats .

HY-P99195

Fasinumab REGN-475; SAR-164877	Trk Receptor	Inflammation/Immunology
Fasinumab (Anti-Human NGF) is a human IgG4 monoclonal antibody to nerve growth factor (NGF). Fasinumab can be used in acute sciatica and knee osteoarthritis (OA) studies .

HY-P99825

Relfovetmab	TNF Receptor	Neurological Disease Inflammation/Immunology
Relfovetmab is an anti-NGF monoclonal antibody (mAb) .

HY-P99820

Ranevetmab NV-01	TNF Receptor	Inflammation/Immunology
Ranevetmab (NV-01) is a caninised anti-NGF monoclonal antibody (mAb). Ranevetmab can alleviate pain, and is used for the research of degenerative joint disease (DJD) pain .

HY-P991711

Povovetug	Trk Receptor	Neurological Disease Inflammation/Immunology
Povovetug is a humanized IgG1κ chimeric monoclonal antibody inhibitor targeting *NGF/bNGF*. Povovetug has a significant analgesic activity. Povovetug can be used for central neuroinflammation like chronic radicular pain research .

HY-P990474

*Anti-NGF/bNGF Antibody* AS2886401-00	Trk Receptor	Inflammation/Immunology
Anti-NGF/bNGF Antibody is a CHO-expressed humanized antibody that targets *NGF/bNGF. Anti-NGF/bNGF Antibody has a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 144.14 kDa. The isotype control for Anti-NGF*/bNGF Antibody can be referenced as Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P99200

Fulranumab	Trk Receptor	Neurological Disease
Fulranumab is a human IgG2 monoclonal antibody against nerve growth factor (NGF) and can be used for the research of pain .

HY-P991622

MNAC13	Trk Receptor	Neurological Disease Inflammation/Immunology
MNAC13 is a kind of mouse IgG1 chimeric antibody, targeting to human TrkA. MNAC13 inhibits the NGF dependent signaling pathway by specifically binding to TrkA receptors. MNAC13 has good analgesic effect and long-lasting efficacy. MNAC13 can be used for researches on inflammatory and chronic pain .

HY-P991324

MEDI-7352	Trk Receptor TNF Receptor	Inflammation/Immunology
MEDI-7352 is a human bispecific antibody (bsAb) targeting NGF/bNGF & TNF. MEDI-7352 can be used in osteoarthritis (OA) pain research .

HY-P991323

MEDI-1912	Trk Receptor Neurokinin Receptor	Inflammation/Immunology
MEDI-1912 is a human monoclonal antibody (mAb) targeting *NGF/bNGF. MEDI-1912 inhibits signaling through TrkA* and p75 receptors. MEDI-1912 can be used in chronic pain research .

HY-P991325

CRB-0089	Trk Receptor	Inflammation/Immunology
CRB-0089 is a human monoclonal antibody (mAb) targeting *NGF/bNGF*. CRB-0089 can be used in analgesia research.

HY-P990749

Luvagrobart AK-115	Trk Receptor	Inflammation/Immunology
Luvagrobart is an anti-NGF human IgG1 κ monoclonal antibody . Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P992273

*Anti-NGF2 Antibody*	Trk Receptor	Inflammation/Immunology
Anti-NGF2 Antibody is a monoclonal antibody targeting NGF2/NT-3. It can be used in ELISA, FACS, and functional assays. For isotype controls of Anti-NGF2 Antibody, please refer to Mouse IgG1 kappa, Isotype Control (HY-P99977).

HY-P992345

DS002	Trk Receptor	Neurological Disease
DS002 is a human monoclonal antibody targeting *NGF/bNGF, with an IC₅₀* of 6.60 nM against human *NGF, 1.98 nM against rat NGF, and 8.46 nM against mouse NGF. DS002 blocks NGF-TrkA* binding, interrupts pain signal transduction, inhibits TrkA-mediated downstream signaling pathways, and alters aromatic amino acid metabolic pathways. DS002 inhibits cancer cell proliferation. DS002 exerts a preventive effect on Paclitaxel-, Cisplatin- and Vincristine-induced peripheral neuropathy in rats. DS002 can be used in studies related to chronic pain and chemotherapy-induced peripheral neuropathy .

HY-P990629

MEDI-578	Inhibitory Antibodies	Inflammation/Immunology
MEDI-578 is a CHO-expressed human antibody that targets *NGF/bNGF*. MEDI-578 has a huIgG2a heavy chain and a huλ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for MEDI-578 can be referenced as Human IgG4 kappa, Isotype Control (HY-P99003).

Art. -Nr.	Produktname	Category	Target	Chemical Structure

HY-N6732

K-252a 25+ Cited Publications SF2370; Antibiotic K 252a; Antibiotic SF 2370	Alkaloids Structural Classification Microorganisms Classification of Application Fields Inflammation/Immunology Disease Research Fields Indole Alkaloids Source Classification	Autophagy PKA PKC Trk Receptor CaMK
K-252a, a staurosporine analog, inhibits protein kinase, with IC₅₀ values of 470 nM, 140 nM, 270 nM, and 1.7 nM for PKC, PKA, Ca ²⁺/calmodulin-dependent kinase type II, and phosphorylase kinase, respectively . K-252a is a potent inhibitor (IC₅₀ of 3 nM) of the tyrosine protein kinase (TRK) activity of the NGF receptor gp140trk, the product of the trk protooncogene .

HY-133968

24-Methylenecholesterol 2 Publications Verification Ostreasterol	Microorganisms other families Animals Classification of Application Fields Anti-aging Marine natural products Other marine organisms Plants Inflammation/Immunology Disease Research Fields Steroids Source Classification	Acyltransferase Reactive Oxygen Species (ROS)
24-Methylenecholesterol (Ostreasterol) is a regulator targeting acyl-CoA cholesterol acyltransferase (ACAT) with anti-aging and neuroprotective effects. 24-Methylenecholesterol mimics the effects of nerve growth factor (NGF), can extend yeast lifespan through an anti-oxidative stress mechanism, and exhibits neuroprotective activity in PC12 cells. 24-Methylenecholesterol can reduce intracellular reactive oxygen species (ROS) and malondialdehyde (MDA) levels, activate anti-oxidative stress pathways (such as UTH1, SOD-related genes), and promote synaptic growth .

HY-N6838

1,1,1,1-Kestohexaose 1,1,1,1-Kestohexose	Polysaccharides other families Classification of Application Fields Other Diseases Plants Disease Research Fields Saccharides Source Classification	Others
1,1,1,1-Kestohexaose (1,1,1,1-Kestohexose) is an insulin-type fructooligosaccharide hexasaccharide. 1,1,1,1-Kestohexaose exhibits neuroprotective and anti-depressant-like activities. 1,1,1,1-Kestohexaose can alleviate Corticosteron (HY-B1618)-induced decrease in cell viability and NGF expression in vitro .

HY-N4285

Negletein 5,6-Dihydroxy-7-methoxyflavone	Flavonoids Flavones Labiatae Phenols Polyphenols Plants Medicago truncatula Gaertn. Source Classification	TNF Receptor Interleukin Related Reactive Oxygen Species (ROS) Keap1-Nrf2 Amyloid-β
Negletein (5,6-Dihydroxy-7-methoxyflavone) is a flavone found in Scutellaria. Negletein shows anti-inflammatory activity via inhibiting TNF-α and IL-1β with IC₅₀ values of 16.4 and 6.4 μM, respectively. Negletein can activate Nrf2 and inhibit ROS production. Negletein can enhance the neuroprotective effect of nerve growth factor. Negletein can inhibit amyloid beta-peptide release and accumulation. Negletein can inhibit pathogens biofilms formation. Negletein can be used for the researches of cancer, infection, inflammation and neurological disease, such as colon cancer and Alzheimer's disease .

HY-N0380

Nardosinone	Neurological Disease Classification of Application Fields Terpenoids Sesquiterpenes Nardostachys jatamansi (D. Don) DC. Plants Valerianaceae Disease Research Fields Source Classification	Others
Nardosinone, isolated from Nardostachys chinensis, is the first enhancer of the neuritogenic action of dbcAMP and staurosporine. Nardosinone may become a useful pharmacological tool for studying the mechanism of action of not only nerve growth factor (NGF) but also both the neuritogenic substances .

HY-117517

NG-012	Microorganisms Classification of Application Fields Phenols Polyphenols Disease Research Fields Source Classification Cancer	Trk Receptor
NG-012, potentiator of nerve growth factor (NGF), were isolated from the culture broth of Penicillium verruculosum F-4542. NG-012 potentiates the neurite outgrowth induced by NGF in rat pheochromocytoma cell line (PC12) .

HY-N12566

Erinacin B	Microorganisms Terpenoids Diterpenoids Source Classification	Others
Erinacin B is a active product that can be extracts from the mycelia of Hericium erinaceum. Erinacin B shows potent stimulating activity of nerve growth factor (NGF)-synthesis .

HY-N3938

Gelsemiol	Iridoids Terpenoids Plants Citrus australasica F.Muell. Source Classification Salicaceae	Others
Gelsemiol is the main active ingredient in Verbena littoralis H. B. K.. Gelsemiol enhanced nerve growth factor (NGF) -induced axonal elongation in PC12D cells .

HY-N15385

Hericenone D	Structural Classification Monophenols Microorganisms Phenols Source Classification	Lipase
Hericenone D, an orally active pancreatic lipase inhibitor, can be found in Hericium erinaceus. Hericenone D reduces lipid absorption and stimulates nerve growth factor *NGF* gene expression. Hericenone D can be used for the research of menopausal obesity .

HY-N3928

Garciniaxanthone E	Flavonoids Garcinia xanthochymus Hook. f. ex T. Anders. Flavonones Guttiferae Plants Source Classification	Others
Garciniaxanthone E is a xanthone compound. Garciniaxanthone E significantly enhances cellular nerve growth factor (NGF)-mediated neurite outgrowth in PC12D cells. Garciniaxanthone E contributes to basic research and medicinal development in neurodegenerative diseases .

HY-N15532

Phenylmethyl 6-O-α-L-arabinofuranosyl-β-D-glucopyranoside	Piperaceae Piper crocatum Ruiz & Pav. Plants Saccharides Monosaccharides Source Classification	Trk Receptor
Phenylmethyl 6-O-α-L-arabinofuranosyl-β-D-glucopyranoside (Compound 12) is a nerve growth factor (NGF) secretion promoter, which is found in plants of the genus Piper. Phenylmethyl 6-O-α-L-arabinofuranosyl-β-D-glucopyranoside is promising for research of neurodegenerative diseases (such as Parkinson's disease and Alzheimer's disease) and diabetic polyneuropathy .

HY-N10325

Sarbronine M	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Disease Research Fields Source Classification	Others
Scabronine M is a novel inhibitor of NGF-induced neurite outgrowth from PC12 cells.

HY-N14417

Indocarbazostatin	Natürliche Produkte Microorganisms Source Classification	Others
Indocarbazostatin against Neurite outgrowth induced by NGF is 6 nM in rat pheochromocytoma PC12 cells .

HY-N14424

Indocarbazostatin B	Natürliche Produkte Microorganisms Source Classification	Others
Indocarbazostatin B against Neurite outgrowth induced by NGF is 24 nM in rat pheochromocytoma PC12 cells .

HY-N12170

Kissoone C	Terpenoids Sesquiterpenes Valeriana officinalis Linn. Plants Valerianaceae Source Classification	Others
Kissoone C (compound 3) is a three-membered ring sesquiterpene isolated from valerian root. Kissoone C can enhance the activity of nerve growth factor (NGF)-mediated neurite outgrowth in PC12D cells .

HY-N0380R

Nardosinone (Standard)	Structural Classification Terpenoids Sesquiterpenes Nardostachys jatamansi (D. Don) DC. Plants Valerianaceae Source Classification	Reference Standards Others
Nardosinone (Standard) is the analytical standard of Nardosinone. This product is intended for research and analytical applications. Nardosinone, isolated from Nardostachys chinensis, is the first enhancer of the neuritogenic action of dbcAMP and staurosporine. Nardosinone may become a useful pharmacological tool for studying the mechanism of action of not only nerve growth factor (NGF) but also both the neuritogenic substances .

HY-133968R

24-Methylenecholesterol (Standard) Ostreasterol (Standard)	Structural Classification Microorganisms other families Animals Marine natural products Other marine organisms Plants Steroids Source Classification	Reference Standards Acyltransferase Reactive Oxygen Species (ROS)
24-Methylenecholesterol (Ostreasterol) (Standard) is the analytical standard of 24-Methylenecholesterol (HY-133968). This product is intended for research and analytical applications. 24-Methylenecholesterol (Ostreasterol) is a regulator targeting acyl-CoA cholesterol acyltransferase (ACAT) with anti-aging and neuroprotective effects. 24-Methylenecholesterol mimics the effects of nerve growth factor (NGF), can extend yeast lifespan through an anti-oxidative stress mechanism, and exhibits neuroprotective activity in PC12 cells. 24-Methylenecholesterol can reduce intracellular reactive oxygen species (ROS) and malondialdehyde (MDA) levels, activate anti-oxidative stress pathways (such as UTH1, SOD-related genes), and promote synaptic growth .

HY-N13170

Glycoside H2	Structural Classification Asclepiadaceae Plants Periploca sepium Bunge Steroids Source Classification	Others
Glycoside H2 is a potentiator of NGF-mediated nerve fiber outgrowth .

HY-N18211

1α,3α-Dihydroxyl-7α-tigloyloxy-12α-ethoxylnimbolinin	Structural Classification Natürliche Produkte Melia azedarach Linn. Plants Meliaceae Source Classification	Drug Derivative
1α,3α-Dihydroxyl-7α-tigloyloxy-12α-ethoxylnimbolinin is a nerve growth factor-enhanced limonoid. 1α,3α-Dihydroxyl-7α-tigloyloxy-12α-ethoxylnimbolinin enhances nerve growth factor-mediated neurite outgrowth in PC12 cells. 1α,3α-Dihydroxyl-7α-tigloyloxy-12α-ethoxylnimbolinin enhances nerve growth factor-mediated neurite outgrowth .

Species:	Human (8) Rat (1) Mouse (5)
Tag:	His (4) Tag Free (9)
Source:	HEK293 (4) CHO (2) E. coli (8)

Art. -Nr.	Compare	Produktname	Species	Source	Image

HY-P700162AF

	*Animal-Free Beta-NGF* Protein, Mouse (His)** beta-NGF; beta-Nerve Growth Factor; NGF; NGFB	Mouse	E. coli
	Nerve Growth Factor-β (Beta-NGF; NGF) is a neurotrophic factor that regulates neuronal survival and differentiation. NGF is also a seminal plasma protein involved in ovulation and luteinizing. NGF has potential functions in the female reproductive system to help overcome the current problem of early embryo loss. Animal-Free Beta-NGF Protein, Mouse (His) is produced by E.coli, with C-terminal His-tag.This product is for cell culture use only.

HY-P704363

	*Beta-NGF* Protein, Mouse (HEK293)** beta-NGF; beta-Nerve Growth Factor; NGF; NGFB	Mouse	HEK293
	Beta-NGF protein is essential for the development and maintenance of the nervous system and binds to NTRK1 and NGFR receptors to initiate signaling cascades that regulate neuronal processes. The NGF precursor proNGF acts as a ligand for the SORCS2-NGFR receptor and activates pathways affecting RAC1/2, the actin cytoskeleton, and neuronal growth. Beta-NGF Protein, Mouse (HEK293) is the recombinant mouse-derived Beta-NGF protein, expressed by HEK293, with tag free.

HY-P70530A

	*Beta-NGF* Protein, Mouse (110a.a, His)** Beta-Nerve Growth Factor; Beta-NGF; NGF; NGFB	Mouse	E. coli
	Beta-NGF protein is essential for the development and maintenance of the nervous system and binds to NTRK1 and NGFR receptors to initiate signaling cascades that regulate neuronal processes.The NGF precursor proNGF acts as a ligand for the SORCS2-NGFR receptor and activates pathways affecting RAC1/2, the actin cytoskeleton, and neuronal growth.Beta-NGF Protein, Mouse (110a.a, His) is the recombinant mouse-derived Beta-NGF protein, expressed by E.coli , with N-6*His labeled tag.

HY-P7660

	*Beta-NGF* Protein, Human (HEK293)** rHuBeta-NGF; Beta-Nerve Growth Factor; Beta-NGF;	Human	HEK293
	Nerve Growth Factor-β (Beta-NGF; NGF) is a neurotrophic factor that regulates neuronal survival and differentiation. NGF is also a seminal plasma protein involved in ovulation and luteinizing. NGF has potential functions in the female reproductive system to help overcome the current problem of early embryo loss. Beta-NGF Protein, Human (HEK293) is produced by HEK293 cells (S122-R239), with tag free.

HY-P70449

	*Beta-NGF* Protein, Human (120a.a)** Beta-Nerve Growth Factor; Beta-NGF; NGF; NGFB	Human	E. coli
	Nerve Growth Factor-β (Beta-NGF; NGF) is a neurotrophic factor that regulates neuronal survival and differentiation. NGF is also a seminal plasma protein involved in ovulation and luteinizing. NGF has potential functions in the female reproductive system to help overcome the current problem of early embryo loss. Beta-NGF Protein, Human (120a.a) is produced by E.coli (S122-A241), with tag free.

HY-P70530

	*Beta-NGF* Protein, Mouse (110a.a)** Beta-Nerve Growth Factor; Beta-NGF; NGF; NGFB	Mouse	E. coli
	Nerve Growth Factor-β (Beta-NGF; NGF) is a neurotrophic factor that regulates neuronal survival and differentiation. NGF is also a seminal plasma protein involved in ovulation and luteinizing. NGF has potential functions in the female reproductive system to help overcome the current problem of early embryo loss. Beta-NGF Protein, Mouse is produced by E.coli (M130-R239), with tag free.

HY-P700018AF

	*Animal-Free Beta-NGF* Protein, Human (His)** β-Nerve Growth Factor; NGF-β	Human	E. coli
	Nerve Growth Factor-β (Beta-NGF; NGF) is a neurotrophic factor that regulates neuronal survival and differentiation. NGF is also a seminal plasma protein involved in ovulation and luteinizing. NGF has potential functions in the female reproductive system to help overcome the current problem of early embryo loss. Animal-Free Beta-NGF Protein, Human (His) is produced by E.coli (S122-A241), with C-terminal His-tag.This product is for cell culture use only.

HY-P73316

	*Beta-NGF* Protein, Human (CHO)** 4 Publications Verification Beta-NGF; Beta-Nerve Growth Factor; NGF; NGFB	Human	CHO
	Nerve Growth Factor-β (Beta-NGF; NGF) is a neurotrophic factor that regulates neuronal survival and differentiation. NGF is also a seminal plasma protein involved in ovulation and luteinizing. NGF has potential functions in the female reproductive system to help overcome the current problem of early embryo loss. Beta-NGF Protein, Human (CHO) is produced by CHO cells (S122-R239), with tag free.

HY-P73317

	*Beta-NGF* Protein, Mouse (CHO)** 2 Publications Verification Beta-NGF; Beta-Nerve Growth Factor; NGF; NGFB	Mouse	CHO
	Nerve Growth Factor-β (Beta-NGF; NGF) is a neurotrophic factor that regulates neuronal survival and differentiation. NGF is also a seminal plasma protein involved in ovulation and luteinizing. NGF has potential functions in the female reproductive system to help overcome the current problem of early embryo loss. Beta-NGF Protein, Mouse (CHO) is produced by CHO cells (S122-G241), with tag free.

HY-P72488

	*pro-Beta-NGF* Protein, Human (223a.a)** Beta-Nerve Growth Factor; Beta-NGF; NGF; NGFB	Human	E. coli
	Pro-Beta-NGF protein plays a crucial role in the development and maintenance of the nervous system by binding to NTRK1 and NGFR receptors. Immature NGF precursors act as ligands for the SORCS2-NGFR complex, triggering signaling pathways affecting RAC1/2, the actin cytoskeleton, and neuronal growth. pro-Beta-NGF Protein, Human (223a.a) is the recombinant human-derived pro-Beta-NGF protein, expressed by E. coli , with tag free.

HY-P702778

	*beta-NGF* Protein, Rat (HEK293, His)** 3 Publications Verification Beta-nerve growth factor; NGF; Beta-NGF; NGFb; beta Nerve Growth Factor	Rat	HEK293
	Nerve Growth Factor-β (Beta-NGF; NGF) is a neurotrophic factor that regulates neuronal survival and differentiation. NGF is also a seminal plasma protein involved in ovulation and luteinizing. NGF has potential functions in the female reproductive system to help overcome the current problem of early embryo loss.

HY-P702535

	Neurotrophin-3 Protein, Human (HEK293) HDNF; MGC129711; Nerve growth factor 2; Neurotrophic factor; neurotrophin 3; neurotrophin-3; NGF2; NGF-2; NT3; NT-3; NTF3	Human	HEK293
	Neurotrophin-3 (NT-3) is crucial for promoting the survival of sensory neurons, specifically those linked to visceral and proprioceptive functions. Its role highlights NT-3's significance in maintaining and supporting the functionality of these specialized sensory cells, emphasizing its potential as a key regulator in the complex network governing essential physiological sensory processes. Neurotrophin-3 Protein, Human (HEK293) is the recombinant human-derived Neurotrophin-3 protein, expressed by HEK293 , with tag free.

HY-P70456

	Neurotrophin-3 Protein, Human 2 Publications Verification Neurotrophin-3; NT-3; HDNF; Nerve Growth Factor 2; NGF-2; Neurotrophic Factor; NTF3	Human	E. coli
	Neurotrophin-3 Protein, Human is a recombinant Neurotrophin-3 protein expressed in E. coli system. Neurotrophin-3 is widely expressed in the nervous system. Neurotrophin-3 reduces cellular damage, improves neuronal regeneration in different models of lesions.

HY-P70456AF

	Animal-Free Neurotrophin-3 Protein, Human Neurotrophin-3; NT-3; HDNF; Nerve Growth Factor 2; NGF-2; Neurotrophic Factor; NTF3	Human	E. coli
	Animal-Free Neurotrophin-3 Protein, Human is a recombinant Neurotrophin-3 protein expressed in E. coli system. Neurotrophin-3 is widely expressed in the nervous system. Neurotrophin-3 reduces cellular damage, improves neuronal regeneration in different models of lesions.

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Art. -Nr.	Produktname	Chemical Structure

HY-A0015S

Bepotastine-d6 besylate
Bepotastine-d₆(besylate) is deuterium labeled Bepotastine (besilate). Bepotastine besilate is a selective and orally active second-generation histamine H1 receptor antagonist, can suppress the expression of nerve growth factor (NGF). Bepotastine besilate has the potential for allergic rhinitis, allergic conjunctivitis and urticaria/pruritus research .

HY-133968S1

24-Methylenecholesterol-13C

24-Methylenecholesterol- ¹³C (Ostreasterol- ¹³C) is the ¹³C labeled 24-Methylenecholesterol (HY-133968) . 24-Methylenecholesterol (Ostreasterol) is a regulator targeting acyl-CoA cholesterol acyltransferase (ACAT) with anti-aging and neuroprotective effects. 24-Methylenecholesterol mimics the effects of nerve growth factor (NGF), can extend yeast lifespan through an anti-oxidative stress mechanism, and exhibits neuroprotective activity in PC12 cells. 24-Methylenecholesterol can reduce intracellular reactive oxygen species (ROS) and malondialdehyde (MDA) levels, activate anti-oxidative stress pathways (such as UTH1, SOD-related genes), and promote synaptic growth .

Host:	Mouse (6) Rabbit (6)
Reactivity:	Human (12) Rat (6) Mouse (6) Zebrafish (1)
Application:	IHC-P (10) ICC/IF (8) IF-Tissue (2) IP (2) IHC-F (2) WB (4) FC (4) ELISA (4)
Isotype:	IgG (6) IgG1 (6)
Conjugation:	Non-conjugated (12)
Clonality:	Monoclonal (7) Recombinant (4)
Modification:	Unmodified (7)

Art. -Nr.	Compare	Produktname	Application	Reactivity	Image

HY-P81121

	NGF Antibody (YA3533) Beta nerve growth factor antibody; Beta NGF antibody; Beta-nerve growth factor antibody; Beta-NGF antibody; HSAN5 antibody; MGC161426 antibody; MGC161428 antibody; Nerve growth factor (beta polypeptide) antibody; Nerve growth factor antibody; Nerve growth factor beta antibody; Nerve growth factor beta polypeptide antibody; Nerve growth factor beta subunit antibody; NGF antibody; NGF_HUMAN antibody; NGFB antibody; NID67 antibody;	WB, IHC-P, IHC-F, ICC/IF, IF-Tissue	Human, Mouse, Rat, Zebrafish
	NGF Antibody (YA3533) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NGF.

HY-P88348

	NT3 (Neurotrophin 3) Antibody (YA8032) HDNF; NGF-2; NGF2; NT-3; NT3	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	NT3 (Neurotrophin 3) Antibody (YA8032) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to NT3 (Neurotrophin 3).

HY-P88348A

	NT3 (Neurotrophin 3) Antibody (YA8032)(PBS only) HDNF; NGF-2; NGF2; NT-3; NT3	IHC-P, ICC/IF	Human, Mouse, Rat
	NT3 (Neurotrophin 3) Antibody (YA8032) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to NT3 (Neurotrophin 3).

HY-P81500

	*p75 NGF* Receptor Antibody (YA1245)** NGFR; TNFRSF16; Tumor necrosis factor receptor superfamily member 16; Gp80-LNGFR; Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; NGF receptor; p75 ICD; CD antigen CD271	IHC-P	Human
	p75 NGF Receptor Antibody (YA1245) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to p75 NGF Receptor.

HY-P84000

	*p75 NGF* Receptor Antibody (YA3697)** CD271; p75NTR; TNFRSF16; p75(NTR); Gp80-LNGFR	IHC-P, FC, ELISA	Human
	p75 NGF Receptor Antibody (YA3697) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to p75 NGF Receptor.

HY-P81500A

	*p75 NGF* Receptor Antibody (YA1245)(PBS only)** NGFR; TNFRSF16; Tumor necrosis factor receptor superfamily member 16; Gp80-LNGFR; Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; NGF receptor; p75 ICD; CD antigen CD271	IHC-P	Human
	p75 NGF Receptor Antibody (YA1245) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to p75 NGF Receptor.

HY-P83999

	*p75 NGF* Receptor Antibody (YA3696)** CD271; p75NTR; TNFRSF16; p75(NTR); Gp80-LNGFR; NGFR	ICC/IF, FC, ELISA	Human
	p75 NGF Receptor Antibody (YA3696) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to p75 NGF Receptor.

HY-P84000A

	*p75 NGF* Receptor Antibody (YA3697)(PBS only)** CD271; p75NTR; TNFRSF16; p75(NTR); Gp80-LNGFR	IHC-P, FC, ELISA	Human
	p75 NGF Receptor Antibody (YA3697) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to p75 NGF Receptor.

HY-P83999A

	*p75 NGF* Receptor Antibody (YA3696)(PBS only)** CD271; p75NTR; TNFRSF16; p75(NTR); Gp80-LNGFR; NGFR	ICC/IF, FC, ELISA	Human
	p75 NGF Receptor Antibody (YA3696) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to p75 NGF Receptor.

HY-P85296

	NGFR p75 Antibody (YA4988) NGFR; TNFRSF16; Tumor necrosis factor receptor superfamily member 16; Gp80-LNGFR; Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; NGF receptor; p75 ICD; CD antigen CD271	IHC-P, IHC-F, ICC/IF, IF-Tissue	Human, Rat, Mouse
	NGFR p75 Antibody (YA4988) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to NGFR p75.

HY-P83029

	*p75 NGF* Receptor Antibody (YA2774)** CD271 antibody; CD271 antigen antibody; Gp80 LNGFR antibody; Gp80-LNGFR antibody; Low affinity nerve growth factor receptor antibody; Low affinity neurotrophin receptor p75NTR antibody; Low-affinity nerve growth factor receptor antibody; Nerve growth factor receptor antibody; Nerve growth factor receptor TNFR superfamily member 16 antibody; NGF receptor antibody; NGFr antibody; p75 ICD antibody; p75 Neurotrophin receptor antibody; p75 NTR antibody; p75(NTR) antibody; p75NTR antibody; TNFR Superfamily Member 16 antibody; TNFRSF16 antibody; TNR16_HUMAN antibody; Tumor necrosis factor receptor superfamily member 16 antibody;	WB, IHC-P, ICC/IF, IP	Human, Mouse, Rat
	p75 NGF Receptor Antibody (YA2774) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to p75 NGF Receptor.

HY-P83029A

	*p75 NGF* Receptor Antibody (YA2774)(PBS only)** CD271 antibody; CD271 antigen antibody; Gp80 LNGFR antibody; Gp80-LNGFR antibody; Low affinity nerve growth factor receptor antibody; Low affinity neurotrophin receptor p75NTR antibody; Low-affinity nerve growth factor receptor antibody; Nerve growth factor receptor antibody; Nerve growth factor receptor TNFR superfamily member 16 antibody; NGF receptor antibody; NGFr antibody; p75 ICD antibody; p75 Neurotrophin receptor antibody; p75 NTR antibody; p75(NTR) antibody; p75NTR antibody; TNFR Superfamily Member 16 antibody; TNFRSF16 antibody; TNR16_HUMAN antibody; Tumor necrosis factor receptor superfamily member 16 antibody;	WB, IHC-P, ICC/IF, IP	Human, Mouse, Rat
	p75 NGF Receptor Antibody (YA2774) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to p75 NGF Receptor.