1. Inhibitory Antibodies
  2. Fulranumab

Fulranumab is a human IgG2 monoclonal antibody against nerve growth factor (NGF) and can be used for the research of pain.

For research use only. We do not sell to patients.

Fulranumab Chemical Structure

Fulranumab Chemical Structure

CAS No. : 902141-80-4

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Description

Fulranumab is a human IgG2 monoclonal antibody against nerve growth factor (NGF) and can be used for the research of pain[1].

IC50 & Target

NGF[1]

In Vitro

Fulranumab (200 μg/mL; 60 min) completely inhibits 10 ng/mL anti-fulranumab monkey polyclonal antibody, inhibits 100 and 1,000 ng/mL of anti-fulranumab antibody by over 90%[1].
Fulranumab (5-100 μg/mL) partially and dose dependently suppresses the false-positive anti-drug antibody (ADA) caused by acid pretreatment NGF[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
CAS No.
SMILES

[Fulranumab]

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Fulranumab
Cat. No.:
HY-P99200
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