1. Apoptosis
    Immunology/Inflammation
  2. TNF Receptor
    Interleukin Related
  3. Negletein

Negletein (Synonyms: 5,6-Dihydroxy-7-methoxyflavone)

Cat. No.: HY-N4285
Handling Instructions

Negletein is a neuroprotectant enhances the action of nerve growth factor and induces neurite outgrowth in PC12 cells. Negletein shows promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 16.4 and 10.8 μM, respectively.

For research use only. We do not sell to patients.

Negletein Chemical Structure

Negletein Chemical Structure

CAS No. : 29550-13-8

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Description

Negletein is a neuroprotectant enhances the action of nerve growth factor and induces neurite outgrowth in PC12 cells. Negletein shows promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 16.4 and 10.8 μM, respectively[1].

Molecular Weight

284.26

Formula

C₁₆H₁₂O₅

CAS No.

29550-13-8

SMILES

O=C1C=C(C2=CC=CC=C2)OC3=CC(OC)=C(O)C(O)=C13

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Negletein5,6-Dihydroxy-7-methoxyflavoneTNF ReceptorInterleukin RelatedTumor Necrosis Factor ReceptorTNFRILneuroprotectantnervegrowth,factoranti-inflammatoryneuriteoutgrowthPC12cellInhibitorinhibitorinhibit

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