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PD 90780 

Cat. No.: HY-110166 Purity: ≥99.0%
Handling Instructions

PD 90780 is a non peptide antagonist of nerve growth factor (NGF) binding to the P75 NGF receptor, inhibits NGF-p75 NTR interaction with IC50s values of 23.1 µM and 1.8 µM in PC12 cells and PC12 nnr5 cells, respectively .

For research use only. We do not sell to patients.

PD 90780 Chemical Structure

PD 90780 Chemical Structure

CAS No. : 77422-99-2

Size Price Stock Quantity
5 mg USD 240 In-stock
Estimated Time of Arrival: December 31
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50 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

PD 90780 is a non peptide antagonist of nerve growth factor (NGF) binding to the P75 NGF receptor, inhibits NGF-p75 NTR interaction with IC50s values of 23.1 µM and 1.8 µM in PC12 cells and PC12 nnr5 cells, respectively [1] .

IC50 & Target

IC50: 23.1 µM (NGF, PC12 cells), 1.8 µM (NGF, PC12 nnr5 cells)

Molecular Weight

362.34

Formula

C₁₉H₁₄N₄O₄

CAS No.

77422-99-2

SMILES

CN1C2=CC(C(O)=O)=NN2C(C3=CC(NC(C4=CC=CC=C4)=O)=CC=C13)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 36 mg/mL (99.35 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7598 mL 13.7992 mL 27.5984 mL
5 mM 0.5520 mL 2.7598 mL 5.5197 mL
10 mM 0.2760 mL 1.3799 mL 2.7598 mL
*Please refer to the solubility information to select the appropriate solvent.
References

Purity: ≥99.0%

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Keywords:

PD 90780PD90780PD-90780OthersInhibitorinhibitorinhibit

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PD 90780
Cat. No.:
HY-110166
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