1. Neuronal Signaling
    Protein Tyrosine Kinase/RTK
  2. Trk Receptor
  3. TRK-IN-18

TRK-IN-18 

Cat. No.: HY-146524
Handling Instructions

TRK-IN-18 is a potent inhibitor of TRK. Tropomyosin-related kinases (Trks) are a family of receptor tyrosine kinases activated by neurotrophins, a group of soluble growth factors including Nerve Growth Factor (NGF), Brain-Derived Neurotrophic Factor (BDNF) and Neurotrophin-3 (NT-3) and Neurotrophin-4/5 (NT-4/5). TRK-IN-18 has the potential for the research of cancer diseases (extracted from patent WO2021148805A1, compound 7).

For research use only. We do not sell to patients.

TRK-IN-18 Chemical Structure

TRK-IN-18 Chemical Structure

CAS No. : 2412008-91-2

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Description

TRK-IN-18 is a potent inhibitor of TRK. Tropomyosin-related kinases (Trks) are a family of receptor tyrosine kinases activated by neurotrophins, a group of soluble growth factors including Nerve Growth Factor (NGF), Brain-Derived Neurotrophic Factor (BDNF) and Neurotrophin-3 (NT-3) and Neurotrophin-4/5 (NT-4/5). TRK-IN-18 has the potential for the research of cancer diseases (extracted from patent WO2021148805A1, compound 7)[1].

Molecular Weight

495.54

Formula

C25H23F2N5O2S

CAS No.
SMILES

CSC1=C(C=C(C=C1)F)[[email protected]]2C[[email protected]@H](CN2C3=NN4C(C(NCC5=CC(O)=CC=C5)=O)=CN=C4C=C3)F

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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TRK-IN-18
Cat. No.:
HY-146524
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