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ST-148 maleate is a potent and orally active DENV inhibitor. ST-148 maleate shows antiviral efficacy and low cell toxicity. ST-148 alters the interaction between lipid droplets and the C protein, thereby inhibiting viral replication. .
ST 1535 is a potent and orally active A2A adenosine receptor antagonist. ST 1535 shows antiparkinsonian activity and antitremorigenic effects. ST 1535 has the potential for the research of Parkinson’s disease .
ST 198 is an orally active D3R antagonist. ST 198 can block the expression of nicotine-induced CPP at doses selective for D3R. ST 198 can be used for the research of neurological disease .
ST-836 hydrochloride (compound 34) is a potent dopamine receptor ligand with Ki values of 4.5 nM, 132 nM for D3 and D2, respectively. ST-836 hydrochloride has the potential for Parkinson’s disease .
ST247 a potent PPARβ/δ inverse agonist. ST247 has a higher affinity to PPARβ/δ. ST247 modulates expression of the activation marker CCL2 in the opposite direction. ST247 efficiently induces the interaction with corepressors. ST247 inhibits the agonist-induced transcriptional activity of PPARβ/δ .
ST 2825 is a specific MyD88 dimerization inhibitor. ST2825 interferes with recruitment of IRAK1 and IRAK4 by MyD88, causing inhibition of IL-1β-mediated activation of NF-κB transcriptional activity .
ST-193 is a potent broad-spectrum arenavirus inhibitor; inhibits Guanarito, Junin, Lassa and Machupo virus with IC50 values of 0.44, 0.62, 1.4 and 3.1 nM, respectively.
ST-193 hydrochloride is a potent broad-spectrum arenavirus inhibitor; inhibits Guanarito, Junin, Lassa and Machupo virus with IC50 values of 0.44, 0.62, 1.4 and 3.1 nM, respectively.
st-Ht31 is a membrane-permeable peptide inhibitor of protein kinase A (PKA) anchoring. st-Ht31 induces robust cholesterol/phospholipid efflux. st-Ht31 completely reverses foam cell formation and restores the metabolic health of macrophage .
ST6 Sialyltransferase 6 (ST6GALNAC6) belongs to the salivary transferase family, which modifies proteins and ceramides on the cell surface, thereby altering intercellular or extracellular matrix interactions. ST6 Sialyltransferase 6 can be used in the study of inflammatory bowel disease (IBD) .
ST4206 is a potent and orally active adenosine A2A receptor antagonist, with Kis of 12 nM and 197 nM for adenosine A2A receptor and adenosine A1 receptor, respectively. ST4206 has the potential for Parkinson׳s disease research .
st-Ht31 ammonium is a membrane-permeable peptide inhibitor of protein kinase A (PKA) anchoring. st-Ht31 ammonium induces robust cholesterol/phospholipid efflux. st-Ht31 ammonium completely reverses foam cell formation and restores the metabolic health of macrophage .
Nestoron (ST-1435) is a 19-norprogesterone derivative with high affinity and selectivity for progesterone receptors. Nestoron is a highly selective and potent progestogen that can be used as a hormonal contraceptive .
Levocarnitine propionate hydrochloride (L-Propionylcarnitine chloride; ST-261) is used to treat the deterioration of renal function, congestive heart failure, intermittent claudication, and other diseases.
ST1936 is a selective, nanomolar affinity 5-HT6 receptor agonist with Ki values of 13 nM, 168 nM and 245 nM for human 5-HT6, 5-HT7 and 5-HT2B receptors, respectively. ST1936 also shows moderate affinity (Ki of 300 nM) for human and rat α2 adrenergic receptor .
Desglymidodrine (ST 1059), the active metabolite of Midodrine (HY-12749), is a selective α1-adrenoceptor agonist. Desglymidodrine is an effective arterial and venous vasoconstrictor and can be used to regulate blood pressure .
ST13 Human Pre-designed siRNA Set A contains three designed siRNAs for ST13 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
ST14 Human Pre-designed siRNA Set A contains three designed siRNAs for ST14 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
ST18 Human Pre-designed siRNA Set A contains three designed siRNAs for ST18 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
ST7 Human Pre-designed siRNA Set A contains three designed siRNAs for ST7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
ST1936 oxalate is a selective, nanomolar affinity 5-HT6 receptor agonist with Ki values of 13 nM, 168 nM and 245 nM for human 5-HT6, 5-HT7 and 5-HT2B receptors, respectively. ST1936 oxalate also shows moderate affinity (Ki of 300 nM) for human and rat α2 adrenergic receptor .
ST271 is a potent inhibitor of protein tyrosine kinase (PTK), inhibits phospholipase D activation stimulated by fMet-Leu-Phe and PAF, with IC50s of 6.7 and 9 μM, respectively.
ST7L Human Pre-designed siRNA Set A contains three designed siRNAs for ST7L gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Tecovirimat(ST-246) is an orally bioavailable antipoxvirus compound; potent and selective active against multiple orthopoxviruses with EC50 about 10 nM. Tecovirimat could be used in the study for orthopoxvirus-induced diseases.
ST3GAL1 Human Pre-designed siRNA Set A contains three designed siRNAs for ST3GAL1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
ST3GAL2 Human Pre-designed siRNA Set A contains three designed siRNAs for ST3GAL2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
ST3GAL3 Human Pre-designed siRNA Set A contains three designed siRNAs for ST3GAL3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
ST3GAL4 Human Pre-designed siRNA Set A contains three designed siRNAs for ST3GAL4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
ST3GAL5 Human Pre-designed siRNA Set A contains three designed siRNAs for ST3GAL5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
ST3GAL6 Human Pre-designed siRNA Set A contains three designed siRNAs for ST3GAL6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
ST6GAL1 Human Pre-designed siRNA Set A contains three designed siRNAs for ST6GAL1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
ST6GAL2 Human Pre-designed siRNA Set A contains three designed siRNAs for ST6GAL2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
ST8SIA1 Human Pre-designed siRNA Set A contains three designed siRNAs for ST8SIA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
ST8SIA2 Human Pre-designed siRNA Set A contains three designed siRNAs for ST8SIA2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
ST8SIA4 Human Pre-designed siRNA Set A contains three designed siRNAs for ST8SIA4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
ST8SIA5 Human Pre-designed siRNA Set A contains three designed siRNAs for ST8SIA5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
ST8SIA6 Human Pre-designed siRNA Set A contains three designed siRNAs for ST8SIA6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Levocarnitine propionate-d5 (hydrochloride) is the deuterium labeled Levocarnitine propionate hydrochloride. Levocarnitine propionate hydrochloride (L-Propionylcarnitine chloride; ST-261) is used to treat the deterioration of renal function, congestive heart failure, intermittent claudication, and other diseases.
Levocarnitine propionate-d3 (hydrochloride) is the deuterium labeled Levocarnitine propionate hydrochloride. Levocarnitine propionate hydrochloride (L-Propionylcarnitine chloride; ST-261) is used to treat the deterioration of renal function, congestive heart failure, intermittent claudication, and other diseases.
alpha-2,8-Sialyltransferase (CstII) (ST8Sia VI) is a member of alpha2,8-sialyltransferase (ST8Sia) family, is often used in biochemical studies. alpha-2,8-Sialyltransferase (CstII) catalyzes elongation of the α2,8-linked oligo/polysialic acid chain on the Sia residue transferred .
Adarotene is an effective apoptosis inducer, which surprisingly produces DNA damage and exhibites a potent antiproliferative activity on a large panel of human tumor cells.
Alinidine hydrobromide is a specific bradycardic agent. Alinidine hydrobromide reduces the slope of the diastolic depolarization in sinoatrial tissue and Purkinje fibers .
Tecovirimat-d4 is a deuterium-labelled Tecovirimat. Tecovirimat is an orally active viral inhibitor with high activity against viruses of the genus Orthopoxvirus, including smallpox, cowpox and monkeypox viruses[1].
Glycoside St-J (Compound 2) is a triterpenoid saponin. Glycoside St-J has antitumor activity and inhibits HeLa cell proliferation. Glycoside St-J Isolates from natural Anemone flaccida. Glycoside St-J can be used in the development of new anticancer agents .
IL6ST Human Pre-designed siRNA Set A contains three designed siRNAs for IL6ST gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
HS2ST1 Human Pre-designed siRNA Set A contains three designed siRNAs for HS2ST1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
HS3ST1 Human Pre-designed siRNA Set A contains three designed siRNAs for HS3ST1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
HS3ST2 Human Pre-designed siRNA Set A contains three designed siRNAs for HS3ST2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
HS3ST4 Human Pre-designed siRNA Set A contains three designed siRNAs for HS3ST4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
HS3ST5 Human Pre-designed siRNA Set A contains three designed siRNAs for HS3ST5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
HS6ST1 Human Pre-designed siRNA Set A contains three designed siRNAs for HS6ST1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
HS6ST2 Human Pre-designed siRNA Set A contains three designed siRNAs for HS6ST2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
HS6ST3 Human Pre-designed siRNA Set A contains three designed siRNAs for HS6ST3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
GAL3ST1 Human Pre-designed siRNA Set A contains three designed siRNAs for GAL3ST1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
GAL3ST4 Human Pre-designed siRNA Set A contains three designed siRNAs for GAL3ST4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
HS3ST3B1 Human Pre-designed siRNA Set A contains three designed siRNAs for HS3ST3B1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
MRS1334 is a potent and selective human adenosine A3 receptor antagonist with Kis of 2.69 nM, >100 nM, >100 nM for hA3, rA1, rA2A, respectively. MRS1334 blocks the protective effect of Cl-IB-MECA leading to significant bradycardia and elevated ST segment . MRS1334 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Revusiran sodium is a 1st-generation short interfering RNA, which directed against transthyretin (TTR) mRNA. Revusiran sodium can be used for transthyretin (TTR)-mediated amyloidosis research .
Revusiran (ALN-TTRSC) is a 1st-generation short interfering RNA, which directed against transthyretin (TTR) mRNA. Revusiran can be used for transthyretin (TTR)-mediated amyloidosis research .
Goflikicept (RPH 104) is a hybrid protein that selectively binds and inactivates both circulating IL-1ß and IL-1α. Goflikicept has the potential for the research of ST-segment elevation myocardial infarction (STEMI) .
Astegolimab (MSTT 1041A; RG 6149) is a human IgG2 monoclonal antibody that blocks IL-33 signaling by targeting ST2, the IL-33 receptor. Astegolimab has the potential for chronic obstructive pulmonary disease (COPD) research .
SKI-I is a potent and selective inhibitor of human sphingosine kinase (SK), with an IC50 of 1.2 μM for ST-hSK. SKI-I also inhibits hERK2 (IC50=11 μM). SKI-I induces apoptosis in tumor cell lines .
alpha-2,6-Sialyltransferase (Pd26ST) (EC 2.4.99.1) is capable of sialylating both terminal and internal galactose and N-acetylgalactosamine, which producing terminal α2,6-sialosides .
10-Undecenal consists of an 11-carbon chain with a double bond between the 9th and 10th carbon atoms and an aldehyde group attached to the 1st carbon atom. This compound has a pungent or fatty smell and is commonly used as a flavoring commodity in foods such as bakery, confectionary and beverages.
Lexatumumab (HGS-ETR 2) is a human agonistic TRAIL receptor 2 (TRAIL-R2, DR5, APO-2) IgG4κ type monoclonal antibody. Lexatumumab induces apoptosis in malignant mesothelioma. Lexatumumab can be used for malignant pleural mesothelioma (MPM) research .
Ethyl (E)-2-hexenoate consists of a six-carbon chain with a double bond between the 2nd and 3rd carbon atoms, an ethyl ester group attached to the 1st carbon atom, and a A methyl group connected by 4 carbon atoms. This compound has a fruity, sweet or floral aroma and is commonly used as a flavoring in foods such as baked goods, confectionary and beverages.
EGFR-IN-7 is a potent, selective and orally active EGFR kinase inhibitor. EGFR-IN-7 has inhibitory effect for for EGFR (WT) and EGFR (mutant C797S/T790M/L858R) with IC50 values of 7.92 nM and 0.218 nM, respectively. EGFR-IN-7 can be used for the research of various cancers .
XY-52 (Compound 32) is a Stimulation-2 (ST2) inhibitor, with an IC50 value of 5.68 μM in AlphaLISA assay, and 4.59 μM in HEK-Blue assay. XY-52 increases proinflammatory T-cell proliferation. XY-52 reduces the plasma sST2 and IFNγ biomarkers in the graft versus host disease (GVHD) mice model .
JAK-2-/3-IN-3 (compound ST4j) is a potent JAK2/3 inhibitor with IC50s of 13.00 and 14.86 nM for JAK2 and JAK3, respectively. JAK-2-/3-IN-3 inhibits autophosphorylation of JAK2 and induces apoptosis in a dose- and time-dependent manner. JAK-2-/3-IN-3 can be used in studies of lymph derived diseases and leukemia .
AZ 12216052 is a mGluR8 positive allosteric modulator, and helps mGluR8 modulate signaling inputing to retinal ganglion cells. AZ 12216052 exhibits antianxiety effect .
ST6 Gal Sialyltransferase 2 (EC:2.4.3.1, ST6GAL2) catalyzes the transfer of sialic acid from CMP to an oligosaccharide substrate. ST6 Gal Sialyltransferase 2 plays an important role in schizophrenic research .
ST3 beta-Gal alpha-2,3-Sialyltransferase 2 (EC:2.4.3.4, ST3GAL2) catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates .
ST3 beta-Gal alpha-2,3-Sialyltransferase 6 (EC:2.4.99., ST3GAL6; SIAT10, Type 2 lactosamine alpha-2,3-sialyltransferase) transfer sialic acid from the activated cytidine 5'-monophospho-N-acetylneuraminic acid to terminal positions on sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins. ST3 beta-Gal alpha-2,3-Sialyltransferase 6 play an important role in cancer .
alpha-2,8-Sialyltransferase (CstII) (ST8Sia VI) is a member of alpha2,8-sialyltransferase (ST8Sia) family, is often used in biochemical studies. alpha-2,8-Sialyltransferase (CstII) catalyzes elongation of the α2,8-linked oligo/polysialic acid chain on the Sia residue transferred .
ST6 Sialyltransferase 1 (EC:2.4.3.3, ST6GALNAC1, SIAT7A, Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1)? transfers a sialic acid, N-acetylneuraminic acid (NeuAc), in an alpha-2,6 linkage to O-linked GalNAc residues. ST6 Sialyltransferase 1 plays an important role in cancer .
10-Undecenal consists of an 11-carbon chain with a double bond between the 9th and 10th carbon atoms and an aldehyde group attached to the 1st carbon atom. This compound has a pungent or fatty smell and is commonly used as a flavoring commodity in foods such as bakery, confectionary and beverages.
Ethyl (E)-2-hexenoate consists of a six-carbon chain with a double bond between the 2nd and 3rd carbon atoms, an ethyl ester group attached to the 1st carbon atom, and a A methyl group connected by 4 carbon atoms. This compound has a fruity, sweet or floral aroma and is commonly used as a flavoring in foods such as baked goods, confectionary and beverages.
Carbohydrate Sulfotransferase 2 (EC:2.8.2.-) can catalyze sulphate transfer to position 6 of non-reducing GlcNAc residues within keratan-like structures on N-linked glycans and within mucin-associated glycans .
Carbohydrate Sulfotransferase 10 (EC:2.8.2.-) can catalyze sulphate transfer to position 3 of terminal glucuronic acid of both protein- and lipid-linked oligosaccharides .
Carbohydrate Sulfotransferase 4 (EC:2.8.2.-) can catalyze sulphate transfer to the hydroxyl group at C-6 position of the non-reducing GlcNAc residue within O-linked mucin-type glycans .
Carbohydrate Sulfotransferase 7 (EC:2.8.2.17) can catalyze sulphate transfer to position 6 of non- GlcNAc residues and to position 6 of the GalNAc residue of chondroitin .
Heparan Sulfate 3-O-Sulfotransferase 1 is a sulfotransferase. Heparan Sulfate 3-O-Sulfotransferase controls cellular production of the anticoagulant heparan sulfate related structure .
Heparan Sulfate Glucosamine 3-O-Sulfotransferase 3 is a sulfotransferase. Heparan Sulfate Glucosamine 3-O-Sulfotransferase 3 is important in heparan sulfate biosynthesis .
CDK2 is a member of the eukaryotic S/T protein kinase family and its function is to catalyze the phosphoryl transfer of ATP γ-phosphate to serine or threonine hydroxyl (denoted as S0/T0) in a protein substrate.
st-Ht31 is a membrane-permeable peptide inhibitor of protein kinase A (PKA) anchoring. st-Ht31 induces robust cholesterol/phospholipid efflux. st-Ht31 completely reverses foam cell formation and restores the metabolic health of macrophage .
st-Ht31 ammonium is a membrane-permeable peptide inhibitor of protein kinase A (PKA) anchoring. st-Ht31 ammonium induces robust cholesterol/phospholipid efflux. st-Ht31 ammonium completely reverses foam cell formation and restores the metabolic health of macrophage .
Tenatumomab (ST2146) is a murine monoclonal antibody against tenascin-C. And tenascin-C, the large extracellular glycoprotein, is overexpressed in cancer. Tenatumomab has been used for Pretargeted Antibody Guided Radioimmunoresearch (PAGRIT), and delivering radionuclides to tumors via PAGRIT and direct 131Iodine labeling approach .
Goflikicept (RPH 104) is a hybrid protein that selectively binds and inactivates both circulating IL-1ß and IL-1α. Goflikicept has the potential for the research of ST-segment elevation myocardial infarction (STEMI) .
Astegolimab (MSTT 1041A; RG 6149) is a human IgG2 monoclonal antibody that blocks IL-33 signaling by targeting ST2, the IL-33 receptor. Astegolimab has the potential for chronic obstructive pulmonary disease (COPD) research .
Lexatumumab (HGS-ETR 2) is a human agonistic TRAIL receptor 2 (TRAIL-R2, DR5, APO-2) IgG4κ type monoclonal antibody. Lexatumumab induces apoptosis in malignant mesothelioma. Lexatumumab can be used for malignant pleural mesothelioma (MPM) research .
Glycoside St-J (Compound 2) is a triterpenoid saponin. Glycoside St-J has antitumor activity and inhibits HeLa cell proliferation. Glycoside St-J Isolates from natural Anemone flaccida. Glycoside St-J can be used in the development of new anticancer agents .
The ST3GAL4 protein, a beta-galactoside alpha2-3 sialyltransferase, crucially sialylates glycoproteins and glycolipids. It mediates hemostasis by sialylating VWF, preventing ASGPR recognition and clearance, and regulates platelet clearance. ST3GAL4 is integral to sialyl Lewis X epitope biosynthesis, facilitating leukocyte adhesion and transendothelial migration. In glycosphingolipid biosynthesis, it sialylates gangliosides, contributing to myelin formation. ST3GAL4 Protein, Human (HEK293, His-HA) is the recombinant human-derived ST3GAL4 protein, expressed by HEK293, with C-His, N-HA labeled tag. The total length of ST3GAL4 Protein, Human (HEK293, His-HA) is 293 a.a., with molecular weight of ~35.4 kDa.
The SULT2A1 protein utilizes PAPS for critical sulfonation of steroids and bile acids in the liver and adrenal glands. Its multifunctional activity extends to a variety of compounds, enhancing its water solubility to facilitate renal excretion. SULT2A1 Protein, Human (His) is the recombinant human-derived SULT2A1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of SULT2A1 Protein, Human (His) is 284 a.a., with molecular weight of 34-38 kDa.
ST6GAL1, a pivotal enzyme, facilitates glycosylation by transferring sialic acid from CMP-sialic acid to galactose-containing acceptor substrates. ST6GAL1 Protein, Human (HEK293, His) is the recombinant human-derived ST6GAL1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of ST6GAL1 Protein, Human (HEK293, His) is 380 a.a., with molecular weight of 41-60 kDa.
ST2/IL1RL1 Protein potently inhibits IL-33 signaling. ST2/IL1RL1 Protein, Human (310a.a, HEK293, His) is the recombinant human-derived ST2/IL1RL1 protein, expressed by HEK293 , with C-His labeled tag. The total length of ST2/IL1RL1 Protein, Human (310a.a, HEK293, His) is 310 a.a., with molecular weight of 52-60 kDa.
ST2/IL1RL1 Protein potently inhibits IL-33 signaling. ST2/IL1RL1 Protein, Human (HEK293) is the recombinant human-derived ST2/IL1RL1 protein, expressed by HEK293 , with tag free. The total length of ST2/IL1RL1 Protein, Human (HEK293) is 310 a.a., with molecular weight of 55-60 kDa.
ST2/IL1RL1 Protein potently inhibits IL-33 signaling. ST2/IL1RL1 Protein, Human (HEK293, Fc) is the recombinant human-derived ST2/IL1RL1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of ST2/IL1RL1 Protein, Human (HEK293, Fc) is 310 a.a., with molecular weight of 75-100 kDa.
ST2/IL1RL1 Protein potently inhibits IL-33 signaling. ST2/IL1RL1 Protein, Human (HEK293, His) is the recombinant human-derived ST2/IL1RL1 protein, expressed by HEK293 , with C-His labeled tag. The total length of ST2/IL1RL1 Protein, Human (HEK293, His) is 310 a.a., with molecular weight of 55-60 kDa.
ST2/IL1RL1 Protein potently inhibits IL-33 signaling. ST2/IL1RL1 Protein, Human (328a.a, HEK293, His) is the recombinant human-derived ST2/IL1RL1 protein, expressed by HEK293 , with C-His labeled tag. The total length of ST2/IL1RL1 Protein, Human (328a.a, HEK293, His) is 310 a.a., with molecular weight of 55-60 kDa.
The ST6GALNAC2 protein is an essential enzyme that catalyzes the transfer of N-acetylneuramidyl groups to glycan chains in glycoproteins. This glycosyltransferase shows a preference for N-acetylgalactosamine (GalNAc) residues that have been modified by the addition of galactose or galactose followed by the addition of sialic acid in an α-2,3 linkage. ST6GALNAC2 Protein, Human (HEK293, His) is the recombinant human-derived ST6GALNAC2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of ST6GALNAC2 Protein, Human (HEK293, His) is 346 a.a., with molecular weight of ~44.0 kDa.
The ST8SIA1 protein links sialic acid to ganglioside GM3 via an α 2,8-bond to form ganglioside GD3. ST8SIA1 Protein, Human (HEK293, His) is the recombinant human-derived ST8SIA1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of ST8SIA1 Protein, Human (HEK293, His) is 308 a.a., with molecular weight of ~48.0 kDa.
Sulfotransferase 1B1 (SULT1B1) is a sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of dopamine, small phenols such as 1-naphthol and p-nitrophenol, thyroid hormones and many xenobiotic compounds. SULT1B1 may play a role in gut microbiota-host metabolic interaction. SULT1B1 Protein, Human (His) is the recombinant human-derived SULT1B1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of SULT1B1 Protein, Human (His) is 296 a.a., with molecular weight of 28-35 kDa.
ST6GAL1 Protein catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing acceptor substrates. ST6GAL1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived ST6GAL1 protein, expressed by HEK293 , with N-His labeled tag. The total length of ST6GAL1 Protein, Mouse (HEK293, His) is 377 a.a., with molecular weight of 50-55 kDa.
The ST2/IL1RL1 protein serves as a receptor for IL-33 and plays a crucial role in immunity and response to environmental stress through IL1RAP. It recruits MYD88, IRAK1/4 and TRAF6 upon stimulation, leading to MAPK phosphorylation. ST2/IL1RL1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived ST2/IL1RL1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of ST2/IL1RL1 Protein, Mouse (HEK293, His) is 311 a.a., with molecular weight of 50-70 kDa.
ST2/IL1RL1 Protein is a member of the Toll-like receptor superfamily, and is a soluble and membrane-bound protein that is the receptor for interleukin 33. It recruits MYD88, IRAK1/4, and TRAF6 after stimulation, leading to MAPK phosphorylation. It is also an inhibitor of interleukin 1 receptor (IL-1RI) and Toll-like receptor 4 (TLR4) signaling, maintaining endotoxin tolerance. ST2/IL1RL1 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived ST2/IL1RL1 protein, expressed by HEK293 , with C-His labeled tag. The total length of ST2/IL1RL1 Protein, Cynomolgus (HEK293, His) is 331 a.a., with molecular weight of ~37.1 kDa.
The ST6GAL1 protein is responsible for facilitating the transfer of sialic acid from CMP-sialic acid to galactose-containing receptor substrates. Sialic acid is an important component of a variety of glycoproteins and glycolipids, and ST6GAL1 protein-mediated sialic acid transfer plays a crucial role in regulating the structure and function of these molecules. ST6GAL1 Protein, Rat (HEK293, His) is the recombinant rat-derived ST6GAL1 protein, expressed by HEK293 , with N-His labeled tag. The total length of ST6GAL1 Protein, Rat (HEK293, His) is 377 a.a., with molecular weight of ~46 kDa.
ST6GALNAC2 Protein, an enzyme, is involved in the process of glycosylation. It adds a specific sugar molecule to proteins and lipids, influencing their functions in cell signaling and adhesion. ST6GALNAC2 Protein is also implicated in certain diseases and may serve as a potential target for therapeutic interventions. ST6GALNAC2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived ST6GALNAC2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of ST6GALNAC2 Protein, Mouse (HEK293, His) is 346 a.a., with molecular weight of ~45.0 kDa.
The ST2/IL1RL1 protein serves as a receptor for IL-33 and plays a crucial role in immunity and response to environmental stress through IL1RAP. It recruits MYD88, IRAK1/4 and TRAF6 upon stimulation, leading to MAPK phosphorylation. ST2/IL1RL1 Protein, Mouse (332a.a, HEK293, Fc) is the recombinant mouse-derived ST2/IL1RL1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of ST2/IL1RL1 Protein, Mouse (332a.a, HEK293, Fc) is 332 a.a., with molecular weight of ~93.2 kDa.
The ST2/IL1RL1 protein serves as a receptor for IL-33 and plays a crucial role in immunity and response to environmental stress through IL1RAP. It recruits MYD88, IRAK1/4 and TRAF6 upon stimulation, leading to MAPK phosphorylation. ST2/IL1RL1 Protein, Mouse (332a.a, HEK293, His) is the recombinant mouse-derived ST2/IL1RL1 protein, expressed by HEK293 , with C-His labeled tag. The total length of ST2/IL1RL1 Protein, Mouse (332a.a, HEK293, His) is 332 a.a., with molecular weight of ~55.7 kDa.
ST3GAL3 protein plays a central role in cellular processes by catalyzing the formation of NeuAc-alpha-2,3-Gal-beta-1,4-GlcNAc-, NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- and NeuAc-α-2,3-Gal-beta-1,3-GalNAc- sequences are present in the terminal carbohydrate groups of glycoproteins and glycolipids. ST3GAL3 Protein, Human (His-SUMO) is the recombinant human-derived ST3GAL3 protein, expressed by E. coli , with N-His, N-SUMO labeled tag. The total length of ST3GAL3 Protein, Human (His-SUMO) is 347 a.a., with molecular weight of ~54.9 kDa.
The SULT1E1 protein is a sulfotransferase that critically regulates estrogen homeostasis by sulfating estradiol and estrone, resulting in hormone inactivation. Its versatility extends to sulfated DHEA, pregnenolone, and xenobiotics such as ethinyl estradiol. SULT1E1 Protein, Human (His) is the recombinant human-derived SULT1E1 protein, expressed by E. coli , with N-His labeled tag. The total length of SULT1E1 Protein, Human (His) is 293 a.a., with molecular weight of ~33 kDa.
Interleukin-24 (IL-24) belongs to the IL10 family of cytokines that selectively induces apoptosis in cancer cells and is recognized during melanoma cell differentiation. IL-24 overexpression increases the expression of GADD family genes and induces cell apoptosis. IL-24 Protein, Human (HEK293, His) is the recombinant human-derived IL-24 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of IL-24 Protein, Human (HEK293, His) is 155 a.a., with molecular weight of ~35 kDa.
IL-24 protein, produced by T-cells, regulates immune responses, tissue homeostasis, defense, and oncogenesis. It induces type I interferon response in influenza infection, signaling through IL20RA/IL20RB or IL20RB/IL22RA1 receptor complexes to stimulate JAK1-STAT3 and MAPK pathways. IL-24 promotes secretion of IL8 and MMP1, maintains ER homeostasis, and serves as a quality control mechanism for the ubiquitin proteasome system. IL-24 Protein, Human (HEK293, Fc) is the recombinant human-derived IL-24 protein, expressed by HEK293 , with C-mFc labeled tag. The total length of IL-24 Protein, Human (HEK293, Fc) is 155 a.a., with molecular weight of ~44.6 KDa.
IL-24 protein, produced by T-cells, regulates immune responses, tissue homeostasis, defense, and oncogenesis. It induces type I interferon response in influenza infection, signaling through IL20RA/IL20RB or IL20RB/IL22RA1 receptor complexes to stimulate JAK1-STAT3 and MAPK pathways. IL-24 promotes secretion of IL8 and MMP1, maintains ER homeostasis, and serves as a quality control mechanism for the ubiquitin proteasome system. Animal-Free IL-24 Protein, Human (His) is the recombinant human-derived animal-FreeIL-24 protein, expressed by E. coli, with C-His labeled tag. The total length of Animal-Free IL-24 Protein, Human (His) is 155 a.a., with molecular weight of ~19.10 kDa.
SULT1A3 protein, a sulfotransferase utilizing PAPS, catalyzes the sulfate conjugation of phenolic monoamines, including neurotransmitters (dopamine, norepinephrine, serotonin) and drugs. This activity contributes significantly to inactivation and elimination, emphasizing SULT1A3's crucial role in regulating neurotransmitter and drug levels, maintaining homeostasis, and ensuring proper biological system functioning. SULT1A3 Protein, Human (His) is the recombinant human-derived SULT1A3 protein, expressed by E. coli , with N-6*His labeled tag. The total length of SULT1A3 Protein, Human (His) is 295 a.a., with molecular weight of ~35.0 kDa.
The SULT2B1 protein uses PAPS to catalyze sulfate conjugation, mainly sulfating cholesterol, and shows significant activity on steroids such as pregnenolone and DHEA. It plays a crucial role in epidermal cholesterol metabolism, regulating epidermal proliferation and differentiation. SULT2B1 Protein, Human (364a.a, His) is the recombinant human-derived SULT2B1 protein, expressed by E. coli , with N-His labeled tag. The total length of SULT2B1 Protein, Human (364a.a, His) is 364 a.a., with molecular weight of ~44 kDa.
The TMED1 protein may facilitate vesicular protein trafficking in the early secretory pathway, acting as a cargo receptor on the luminal side to incorporate secretory cargo into transport vesicles. It is involved in the formation of the vesicle shell on the cytoplasmic side and positively affects IL-33-mediated IL-8 and IL-6 production by interacting with IL1RL1. TMED1 Protein, Human (171a.a, HEK293, Fc) is the recombinant human-derived TMED1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of TMED1 Protein, Human (171a.a, HEK293, Fc) is 171 a.a., with molecular weight of 55-65 kDa.
CD82, a vital immune response participant, engages with CD4 or CD8 to provide crucial costimulatory signals in the TCR/CD3 pathway. Its direct interaction with IGSF8 plays a pivotal role in modulating immune functions and mediating cellular responses. CD82 Protein, Human (HEK293, Fc) is the recombinant human-derived CD82 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of CD82 Protein, Human (HEK293, Fc) is 123 a.a., with molecular weight of 40-60 kDa.
CD82, a vital immune response participant, engages with CD4 or CD8 to provide crucial costimulatory signals in the TCR/CD3 pathway. Its direct interaction with IGSF8 plays a pivotal role in modulating immune functions and mediating cellular responses. CD82 Protein, Human (HEK293, His) is the recombinant human-derived CD82 protein, expressed by HEK293, with C-His labeled tag. The total length of CD82 Protein, Human (HEK293, His) is 118 a.a., with molecular weight of 25-33 kDa.
LRP-12, a probable receptor, potentially facilitates the internalization of lipophilic molecules and signal transduction. It may function as a tumor suppressor and interacts with proteins RACK1, ZFYVE9, and NMRK2. LRP-12 Protein, Human (HEK293, His) is the recombinant human-derived LRP-12 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of LRP-12 Protein, Human (HEK293, His) is 456 a.a., with molecular weight of ~64-85 kDa.
The SULT1C2 protein utilizes PAPS to catalyze sulfate conjugation and has specific affinity for sulfonated p-nitrophenol. It selectively avoids sulfonated steroids, dopamine, acetaminophen or alpha-naphthol. SULT1C2 Protein, Human (His) is the recombinant human-derived SULT1C2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of SULT1C2 Protein, Human (His) is 296 a.a., with molecular weight of ~38.0 kDa.
SULT4A1 Protein, an atypical sulfotransferase, shows low PAPS affinity and minimal catalytic activity toward substrates like L-triiodothyronine and estrone. Despite limited efficiency, SULT4A1 may impact drug and neurotransmitter metabolism in the central nervous system (CNS). SULT4A1 Protein, Human is the recombinant human-derived SULT4A1 protein, expressed by E. coli , with tag free. The total length of SULT4A1 Protein, Human is 284 a.a., with molecular weight of ~34.0 kDa.
The SULT2B1 protein uses PAPS to catalyze sulfate conjugation, mainly sulfating cholesterol, and shows significant activity on steroids such as pregnenolone and DHEA. It plays a crucial role in epidermal cholesterol metabolism, regulating epidermal proliferation and differentiation. SULT2B1 Protein, Human (311a.a, His) is the recombinant human-derived SULT2B1 protein, expressed by E. coli , with C-6*His labeled tag. The total length of SULT2B1 Protein, Human (311a.a, His) is 311 a.a., with molecular weight of ~35.0 kDa.
Sulfotransferase 1A2 (SULT1A2) is a phenol sulfotransferase with thermostable enzyme activity. SULT1A2 utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. SULT1A2 is also responsible for the sulfonation and activation of minoxidil. SULT1A2 induces the mutagenicity and carcinogenicity of certain substrates by influencing DNA adduct formation. SULT1A2 Protein, Human (His) is the recombinant human-derived SULT1A2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of SULT1A2 Protein, Human (His) is 295 a.a., with molecular weight of ~33.0 kDa.
KLF6 Protein, a transcriptional activator, binds GC box motifs and may contribute to B-cell growth and development. It interacts with ZZEF1. KLF6 Protein, Human is the recombinant human-derived KLF6 protein, expressed by E. coli , with tag free. The total length of KLF6 Protein, Human is 109 a.a., with molecular weight of ~16.0 kDa.
CHST5 protein, utilizing PAPS, catalyzes sulfate transfer to position 6 of non-reducing GlcNAc residues in keratan, particularly in the cornea. This sulfonation is crucial for mediating keratan sulfate sulfation, a key process in maintaining corneal transparency. CHST5 acts on short and long carbohydrate substrates, emphasizing its role in corneal function and contribution to maintaining corneal transparency through keratan sulfate sulfation. CHST5 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CHST5 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of CHST5 Protein, Mouse (HEK293, Fc) is 369 a.a., with molecular weight of ~70.1 KDa.
Glycoprotein 130 (gp130) is a trans-membrane protein, is the common signal-transducing receptor subunit of the interleukin-6 (IL-6) family. gp130 inhibits the cell growth and migration, decreases the STAT3 phosphorylation induced by IL-6, and decreases IL-6-induced increase of Ki67. gp130 shows anti-tumor, anti-inflammation and anti-nociceptive activity. gp130/IL6ST Protein, Human (HEK293) is a recombinant protein consisting of 596 amino acids (M23-I618) and is produced by HEK293 cells.
Glycoprotein 130 (gp130) is a trans-membrane protein, is the common signal-transducing receptor subunit of the interleukin-6 (IL-6) family. gp130 inhibits the cell growth and migration, decreases the STAT3 phosphorylation induced by IL-6, and decreases IL-6-induced increase of Ki67. gp130 shows anti-tumor, anti-inflammation and anti-nociceptive activity. gp130/IL6ST Protein, Human (HEK293, Fc) is a recombinant protein with a Fc label that consists of 618 amino acids (M1-I618) and is produced by HEK293 cells.
gp130/IL6ST is an important signal transduction molecule that can form high-affinity receptor complexes for cytokines such as IL6, LIF, and OSM. Upon IL6 binding, gp130/IL6ST homodimerizes and activates the JAK-MAPK and JAK-STAT3 pathways, leading to the phosphorylation of IL6ST tyrosine residues and subsequent activation of STAT3. gp130/IL6ST Protein, Human (HEK293, His) is the recombinant human-derived gp130/IL6ST protein, expressed by HEK293 , with C-His labeled tag. The total length of gp130/IL6ST Protein, Human (HEK293, His) is 597 a.a., with molecular weight of 80-110 kDa.
Glycoprotein 130 (gp130) is a trans-membrane protein, is the common signal-transducing receptor subunit of the interleukin-6 (IL-6) family. gp130 inhibits the cell growth and migration, decreases the STAT3 phosphorylation induced by IL-6, and decreases IL-6-induced increase of Ki67. gp130 shows anti-tumor, anti-inflammation and anti-nociceptive activity. gp130/IL6ST Protein, Human (HEK293, His-Fc) is a recombinant protein with a His-Fc label that consists of 618 amino acids (M1-I618) and is produced by HEK293 cells.
Glycoprotein 130 (gp130) is a trans-membrane protein, is the common signal-transducing receptor subunit of the interleukin-6 (IL-6) family. gp130 inhibits the cell growth and migration, decreases the STAT3 phosphorylation induced by IL-6, and decreases IL-6-induced increase of Ki67. gp130 shows anti-tumor, anti-inflammation and anti-nociceptive activity. gp130/IL6ST Protein, Rhesus Macaque (HEK293, Fc) is a recombinant protein with a Fc label that consists of 618 amino acids (M1-I618) and is produced by HEK293 cells.
Glycoprotein 130 (gp130) is a trans-membrane protein, is the common signal-transducing receptor subunit of the interleukin-6 (IL-6) family. gp130 inhibits the cell growth and migration, decreases the STAT3 phosphorylation induced by IL-6, and decreases IL-6-induced increase of Ki67. gp130 shows anti-tumor, anti-inflammation and anti-nociceptive activity. gp130/IL6ST Protein, Rhesus Macaque (HEK293, His) is a recombinant protein with a His label that consists of 618 amino acids (M1-I618) and is produced by HEK293 cells.
Glycoprotein 130 (gp130) is a trans-membrane protein, is the common signal-transducing receptor subunit of the interleukin-6 (IL-6) family. gp130 inhibits the cell growth and migration, decreases the STAT3 phosphorylation induced by IL-6, and decreases IL-6-induced increase of Ki67. gp130 shows anti-tumor, anti-inflammation and anti-nociceptive activity. gp130/IL6ST Protein, Mouse (595a.a, HEK293, His) is a recombinant protein with a His label that consists of 595 amino acids (Q23-E617) and is produced by HEK293 cells.
The CHST15 protein is a sulfotransferase that catalyzes the transfer of sulfate to GalNAc 4-sulfate in chondroitin sulfate A to form chondroitin sulfate E with GlcA-GalNAc(4,6-SO(4)) units. It also sulfates the unique non-reducing terminal sequence GalNAc(4SO4)-GlcA(2SO4)-GalNAc(6SO4), similar to thrombomodulin chondroitin sulfate. CHST15 Protein, Human (HEK293, His) is the recombinant human-derived CHST15 protein, expressed by HEK293 , with N-His labeled tag. The total length of CHST15 Protein, Human (HEK293, His) is 463 a.a., with molecular weight of 70-80 KDa.
CHST11 Protein catalyzes sulfate transfer to position 4 of the GalNAc residue in chondroitin, the main proteoglycan in cartilage and cell surfaces. It can sulfate Gal residues in desulfated dermatan sulfate, with a preference for GlcA->GalNAc units over IdoA->GalNAc units, and does not form 4,6-di-O-sulfated GalNAc when chondroitin sulfate C is the acceptor. CHST11 Protein, Human (sf9, His) is the recombinant human-derived CHST11 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of CHST11 Protein, Human (sf9, His) is 312 a.a., with molecular weight of ~43 KDa.
Glycoprotein 130 (gp130) is a trans-membrane protein, is the common signal-transducing receptor subunit of the interleukin-6 (IL-6) family. gp130 inhibits the cell growth and migration, decreases the STAT3 phosphorylation induced by IL-6, and decreases IL-6-induced increase of Ki67. gp130 shows anti-tumor, anti-inflammation and anti-nociceptive activity. gp130/IL6ST Protein, Mouse (617a.a, HEK293, His) is a recombinant protein with a His label and is produced by HEK293 cells.
Glycoprotein 130 (gp130) is a trans-membrane protein, is the common signal-transducing receptor subunit of the interleukin-6 (IL-6) family. gp130 inhibits the cell growth and migration, decreases the STAT3 phosphorylation induced by IL-6, and decreases IL-6-induced increase of Ki67. gp130 shows anti-tumor, anti-inflammation and anti-nociceptive activity. gp130/IL6ST Protein, Rat (HEK293, His) is a recombinant protein with a His label that consists of 614 amino acids (M4-E618) and is produced by HEK293 cells.
The CHST3 protein utilizes PAPS to keyly catalyze the transfer of sulfate to position 6 of GalNAc in chondroitin, the major proteoglycan in cartilage. CHST3 also sulfonates Gal residues in keratan sulfate and sialic acid LacNAc oligosaccharides with less efficiency. CHST3 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CHST3 protein, expressed by HEK293 , with N-His labeled tag. The total length of CHST3 Protein, Mouse (HEK293, His) is 434 a.a., with molecular weight of 55-75 KDa.
Glycoprotein 130 (gp130) is a trans-membrane protein, is the common signal-transducing receptor subunit of the interleukin-6 (IL-6) family. gp130 inhibits the cell growth and migration, decreases the STAT3 phosphorylation induced by IL-6, and decreases IL-6-induced increase of Ki67. gp130 shows anti-tumor, anti-inflammation and anti-nociceptive activity. gp130/IL6ST Protein, Rat (HEK293, His-Fc) is a recombinant protein with a His-Fc label that consists of 614 amino acids (M4-E618) and is produced by HEK293 cells.
The HS3ST1 protein utilizes PAPS to crucially catalyze the transfer of sulfate to position 3 of the glucosamine residue in heparan sulfate (HS), representing the rate-limiting step in HS biosynthesis. This activity is essential for the formation of the anticoagulant heparan sulfate and completion of the antithrombin pentasaccharide binding site. HS3ST1 Protein, Human (sf9, His) is the recombinant human-derived HS3ST1 protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of HS3ST1 Protein, Human (sf9, His) is 287 a.a., with molecular weight of ~36 KDa.
Glycoprotein 130 (gp130) is a trans-membrane protein, is the common signal-transducing receptor subunit of the interleukin-6 (IL-6) family. gp130 inhibits the cell growth and migration, decreases the STAT3 phosphorylation induced by IL-6, and decreases IL-6-induced increase of Ki67. gp130 shows anti-tumor, anti-inflammation and anti-nociceptive activity. gp130/IL6ST Protein, Mouse (617a.a, HEK293, Fc) is a recombinant protein with a Fc label that consists of 617 amino acids (M1-E617) and is produced by HEK293 cells.
Levocarnitine propionate-d3 (hydrochloride) is the deuterium labeled Levocarnitine propionate hydrochloride. Levocarnitine propionate hydrochloride (L-Propionylcarnitine chloride; ST-261) is used to treat the deterioration of renal function, congestive heart failure, intermittent claudication, and other diseases.
Tecovirimat-d4 is a deuterium-labelled Tecovirimat. Tecovirimat is an orally active viral inhibitor with high activity against viruses of the genus Orthopoxvirus, including smallpox, cowpox and monkeypox viruses[1].
Levocarnitine propionate-d5 (hydrochloride) is the deuterium labeled Levocarnitine propionate hydrochloride. Levocarnitine propionate hydrochloride (L-Propionylcarnitine chloride; ST-261) is used to treat the deterioration of renal function, congestive heart failure, intermittent claudication, and other diseases.