Sulfotransferase 2A1 Antibody (YA1861)
(Synonyms: HST; ST2; STD; hSTa; DHEAS; ST2A1; ST2A3; DHEA-ST)
Based on 1 Customer Validation
Sulfotransferase 2A1 Antibody (YA1861) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Sulfotransferase 2A1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF, FC
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in rabbit IgG in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|---|---|
| Dilution Ratio | 1:1000-1:2000 | 1:100-1:200 | 1:50-1:200 | 1:50-1:100 |
Product Details
Sulfotransferase 2A1 Antibody (YA1861) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Sulfotransferase 2A1.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 34 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 34 kDa
Entrez Gene: 6822 Human ; 20859 Mouse ; 24912 Rat
SwissProt: Q06520 Human ; P52843 Mouse ; P15709 Rat
OMIM: 125263 Human
A synthesized peptide derived from human SULT2A1 aa234-285.
Endogenous
Affinity Chromatography
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in rabbit IgG in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Sulfotransferase 2A1 is a Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfonation of steroids and bile acids in the liver and adrenal glands. Mediates the sulfation of a wide range of steroids and sterols, including pregnenolone, androsterone, DHEA, bile acids, cholesterol and as well many xenobiotics that contain alcohol and phenol functional groups. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Plays an important role in maintening steroid and lipid homeostasis. Plays a key role in bile acid metabolism. In addition, catalyzes the metabolic activation of potent carcinogenic polycyclic arylmethanols[1][2][3][4][5][6][7][8].
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Subcellular Localization
Cytoplasm
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Expression
Tissue_specificity:Liver, adrenal and at lower level in the kidney. Is present in human fetus in higher level in the adrenal than the liver and the kidney -
Subunit
Homodimer
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SwissProt ID
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Synonyms
HST; ST2; STD; hSTa; DHEAS; ST2A1; ST2A3; DHEA-ST
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Research Field
Signal Transduction
Documentation
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