ST638
ST638 is a potent tyrosine kinase inhibitor (IC50=370 nM). ST638 also targets the CSF-1 receptor and inhibits PGE2 production.
For research use only. We do not sell to patients.
- CAS No.: 107761-24-0
- Formula: C19H18N2O3S
- Molecular Weight:354.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 107761-24-0
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Molecular Weight 354.42
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Formula C19H18N2O3S
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SMILES
O=C(N)/C(C#N)=C/C1=CC(CSC2=CC=CC=C2)=C(O)C(OCC)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Puri J, et al. Selective inhibition of PGE2 production in cells transfected with c-fms encoded CSF-1 receptor genes by the tyrosine kinase inhibitor, ST638. Agents Actions. 1991 Jul;33(3-4):314-7. [Content Brief]
[2]. Fuortes M, et al. Adhesion-dependent protein tyrosine phosphorylation in neutrophils treated with tumor necrosis factor. J Cell Biol. 1993 Feb;120(3):777-84. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)