Search Result
Results for "
radical-scavenging
" in MedChemExpress (MCE) Product Catalog:
1
Biochemical Assay Reagents
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-N2625A
-
|
Cytochrome P450
|
Others
|
Harmalol hydrochloride, a beta carboline alkaloid, presents in several medicinal plants such as Peganum harmala. Harmalol hydrochloride, main metabolite of Harmaline, significantly inhibits the dioxin-mediated induction of CYP1A1 at the transcriptional and posttranslational levels. Harmalol hydrochloride possesses antioxidant and hydroxyl radical-scavenging properties .
|
-
-
- HY-N3289
-
|
Others
|
Others
|
Methyl 3,4,5-trimethoxycinnamate (Compound III) is a natural compound with hydroxyl radical-scavenging effects .
|
-
-
- HY-N12291
-
|
Others
|
Others
|
7,4'-Dihydroxyhomoisoflavane is a natural antioxidant. 7,4'-Dihydroxyhomoisoflavane has ABTS radical-scavenging capacity with an IC50 of 0.22 mg/mL .
|
-
-
- HY-N9387
-
-
-
- HY-N7155
-
|
Reactive Oxygen Species
|
Inflammation/Immunology
|
2,4,7-Trihydroxy-9,10-dihydrophenanthrene is a dihydrophenanthrene derivative that can be isolated from the air-dried whole plant of Pholidota chinensis Lindl.. 2,4,7-Trihydroxy-9,10-dihydrophenanthrene shows potent activities of IC50 at 16.2 μM in DPPH radical-scavenging assay .
|
-
-
- HY-N3141
-
(-)-Olivile; Vladinol C
|
Others
|
Others
|
Olivil ((-)-Olivile) is a lignan that has weak DPPH radical-scavenging activity (EC50: 176 μM) .
|
-
-
- HY-N1354
-
Quercetin-3-D-xyloside; Reinutrin
|
Reactive Oxygen Species
|
Metabolic Disease
|
Reynoutrin (Quercetin-3-D-xyloside) is a flavonoid from Psidium cattleianum, with antioxidant and radical-scavenging activity .
|
-
-
- HY-N9289
-
|
Others
|
Inflammation/Immunology
|
Vitedoin A is a phenyldihydronaphthalene-type lignan. Vitedoin A has antioxidative activity and radical-scavenging effect. Vitedoin A can be isolated from Vitex negundo .
|
-
-
- HY-N10770
-
|
Others
|
Metabolic Disease
|
5'-Geranyl-5,7,2',4'-tetrahydroxyflavone, a phenolic compound, presents strong oxygen radical absorbance capacity (ORAC), DPPH radical-scavenging capacity, ABTS radical-scavenging capacity, ferric reducing antioxidant power (FRAP) and nitrite-scavenging capacity. 5'-Geranyl-5,7,2',4'-tetrahydroxyflavone has the potential for natural antioxidant research .
|
-
-
- HY-N1094
-
|
PARP
MDM-2/p53
|
Inflammation/Immunology
|
Verminoside is an iridoid isolated from Kigelia africana, exhibits anti-inflammatory and remarkable antioxidant activity with a radical-scavenging activity of 2.5 μg/mL. The genotoxicity of Verminoside on human lymphocytes is associated with elevated levels of PARP-1 and p53 proteins .
|
-
-
- HY-N10742
-
|
Reactive Oxygen Species
|
Cardiovascular Disease
|
Maritimein is an aurone that can be isolated from Coreopsis tinctoria. Maritimein shows strong diphenyl(2,4,6-trinitrophenyl)iminoazanium (DPPH) radical-scavenging activity with an IC50 value of 4.12 μM. Maritimein can be used for the research of cardiovascular disease .
|
-
-
- HY-156711
-
|
Others
|
Inflammation/Immunology
|
Ternatumoside II is a flavonoid glycoside that can be isolated from R. crenulata. Ternatumoside II can stimulate IFN-γ expression. Ternatumoside II has radical-scavenging activities (IC50s: 260.5 μM and 320.2 μM for DPPH and ABTS) .
|
-
-
- HY-136593
-
(S)-3-(4-Hydroxyphenyl)lactic acid
|
Others
|
Others
|
(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid (compound 1) is a metabolite isolated from the culture medium of Leuconostoc mesenteroides. (S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid has high DPPH radical-scavenging activities and antioxidative activities .
|
-
-
- HY-121153
-
Alutenusin
|
FXR
|
Others
|
Altenusin shows markedly DPPH radical scavenging activities.
|
-
-
- HY-N8193
-
-
-
- HY-76779
-
|
Others
|
Cancer
|
4-(Chloromethyl)-7-hydroxycoumarin (compound 4) is a hydroxycoumarin derivative with potent antioxidant effect and high hydroxyl radical-scavenging property. 4-(Chloromethyl)-7-hydroxycoumarin contains a methyl group and a chlorine group in the heterocyclic ring. A series of coumarins incorporating hydroxy-, chloro- and/or chloromethyl-moieties has been investigated as potent inhibitors of the zinc enzyme carbonic anhydrase, expecially tumor-associated isoforms CA IX and XII .
|
-
-
- HY-N1412
-
-
-
- HY-112879
-
-
-
- HY-N3670
-
Isoolivil
|
Others
|
Cardiovascular Disease
|
Cycloolivil (Isoolivil) is a natural polyphenolic compound with a significant radical scavenging activity. Antioxidant and Antiaggregant effects .
|
-
-
- HY-W018643A
-
Methyl (E)-ferulate
|
Others
|
Others
|
(E)-Ferulic acid methyl ester (Methyl (E)-ferulate) exhibits strong DPPH and ABTS + radical scavenging activities .
|
-
-
- HY-N4177
-
|
Others
|
Metabolic Disease
|
Rubrofusarin gentiobioside is isolated from the seeds of Cassia tora L. Rubrofusarin gentiobioside has a radical scavenging effect .
|
-
-
- HY-N3858
-
|
Others
|
Inflammation/Immunology
|
Erythristemine is an alkaloid that can be isolated from Erythrina lysistemon. Erythristemine has weak DPPH radical scavenging properties .
|
-
-
- HY-N6043
-
|
Others
|
Inflammation/Immunology
|
Hydroxytyrosol acetate is found in the olive oil with an antioxidant activity. Hydroxytyrosol acetate had a weaker DPPH radical scavenging activity than hydroxytyrosol .
|
-
-
- HY-111523
-
|
Others
|
Metabolic Disease
|
Isomahanine, carbazole alkaloid, is an antioxidative agent. Isomahanine has DPPH radical scavenging activity with an IC50 value of 24 μM .
|
-
-
- HY-N8274
-
|
Others
|
Inflammation/Immunology
|
Flavidin, an aromatic compound, can be isolated from Coelogyne longipe. Flavidin is an antioxidant, and has radical scavenging activity .
|
-
-
- HY-N0499A
-
|
Others
|
Inflammation/Immunology
|
Cyanidin, an antioxidant, has protective effect on DNA cleavage, free radical scavenging activity and significant inhibition of XO activity .
|
-
-
- HY-B1001
-
-
-
- HY-B1001A
-
-
-
- HY-N9068
-
|
Fungal
|
Infection
|
Alterlactone is an antimicrobial. Alterlactone shows broad antimicrobial activity against bacterial and fungal. Alterlactone has strong radical scavenging activity .
|
-
-
- HY-N7931
-
-
-
- HY-N4246
-
|
Others
|
Neurological Disease
|
Bacopaside I, a saponin isolated from Bacopa monnieri, exbibits antioxidant properties and free radical scavenging capacity and exerts antidepressant-like effect .
|
-
-
- HY-N3985
-
|
Others
|
Cancer
|
Gyrophoric acid is a good ultraviolet filter in lichen populations. Gyrophoric acid shows DPPH radical scavenging activity with an IC50 value of 105.75 µg/ml .
|
-
-
- HY-133183
-
|
Others
|
Others
|
Urolignoside is an antioxidant with free radical scavenging activity. Urolignoside potently scavenges DPPH radical, and exhibits antioxidant to β-carotene-lineoleate model .
|
-
-
- HY-N3349A
-
|
Others
|
Others
|
(-)-Lyoniresinol is a lignan isolated from the Tarenna attenuata with antioxidant activities. (-)-Lyoniresinol has radical scavenging activities against DPPH with an IC50 of 82.4 μM .
|
-
-
- HY-125944
-
|
Mitochondrial Metabolism
|
Others
|
Mito-TEMPO is a mitochondria-targeted antioxidant that possesses superoxide and alkyl radical scavenging properties. Mito-TEMPO helps protect against oxidative damage to the mitochondria .
|
-
-
- HY-N3349
-
|
Others
|
Others
|
Lyoniresinol is a lignan isolated from the Tarenna attenuata with antioxidant activities. Lyoniresinol has radical scavenging activities against DPPH with an IC50 of 82.4 μM .
|
-
-
- HY-N8169
-
|
Others
|
Others
|
10-O-Trans-p-methoxycinnamoylcatalpol has antioxidant activity with the IC50 value of 0.37 μM/mL in DPPH free radical scavenging assay .
|
-
-
- HY-W021267
-
|
Reactive Oxygen Species
|
Inflammation/Immunology
|
3-Demethylcolchicine, a colchicine metabolite, possesses a hydroxy-group on its carbon ring that could participate in radical scavenging and markedly inhibits the carrageenin edema .
|
-
-
- HY-N9447
-
-
-
- HY-N4111
-
|
Others
|
Inflammation/Immunology
Cancer
|
Wushanicaritin exhibits significant antioxidant activity (IC50=35.3 μM) in DPPH radical scavenging activity tests. Antitumor effects and anti-inflammatory property .
|
-
-
- HY-N11469
-
|
Others
|
Others
|
Cyclobisdemethoxycurcumin is an antioxidant agent with IC50s of ~250 μM and 15-20 μM in DPPH radical scavenging assay and 2-DR oxidation assay, respectively .
|
-
-
- HY-N0026
-
2'-AA
|
Others
|
Others
|
2'-Acetylacteoside is a phenylethanoid glycoside isolated from Brandisia hancei, inhibits free radical-induced hemolysis of red blood cells and exhibits free radical scavenging activity .
|
-
-
- HY-N7518
-
|
Others
|
Inflammation/Immunology
|
Eulophiol shows the 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity with an EC50 of 27.7μM. Antioxidant activity .
|
-
-
- HY-N1859
-
|
|
|
3'-O-Methylorobol, an antioxidant flavonoid, exhibits moderate antioxidant activity in the 2,2-diphenyl-1-picrylhydrazyl free radical scavenging assay .
|
-
-
- HY-P1512
-
|
SOD
|
Cancer
|
Antioxidant peptide A is a short peptide, which contains alternative aromatic or sulfur-containing amino acid. The side chains of Antioxidant peptide A are believed to contribute to strong radical scavenging activities of peptides in the cancer cell.
|
-
-
- HY-N8194
-
Syringetin 3-O-β-D-glucoside
|
Others
|
Neurological Disease
|
Syringetin-3-O-glucosid (Syringetin 3-O-β-D-glucoside), a flavonol glycoside, shows relatively weak DPPH and ABTS radical scavenging activity .
|
-
-
- HY-N11552
-
|
Glutathione Peroxidase
|
Inflammation/Immunology
|
Sorbifolin, a flavone glucoside, can be isolated from the Pterogyne nitens. Sorbifolin has myeloperoxidase inhibitory and radical scavenging activities. Sorbifolin is also a MPO inhibitor with an IC50 value of 19.2 nM .
|
-
-
- HY-N4168B
-
|
Others
|
Cancer
|
Methyl chlorogenate is an antioxidant, and has radical scavenging activity. Methyl chlorogenate is an anti-inflammatory agent. Methyl chlorogenate also inhibits hepatocellular carcinoma (HCC) cell proliferation and metastasis .
|
-
-
- HY-N7080
-
Hydroferulic acid
|
Others
|
Metabolic Disease
|
Dihydroferulic acid (Hydroferulic acid) is one of the main metabolites of curcumin and antioxidant/radical-scavenging properties with an IC50 value of 19.5 μM. Dihydroferulic acid is a metabolite of human gut microflora as well as a precursor of vanillic acid .
|
-
-
- HY-130294
-
|
Elastase
|
Inflammation/Immunology
|
Pyracrenic acid is an elastase inhibitor (IC50 = 2.42 µM), can be obtained from the bark of Pyracantha crenulata. Pyracrenic acid has DPPH free radical scavenging activity and anti-inflammatory activity .
|
-
- HY-N8846
-
|
Fungal
|
Infection
|
dl-Aloesol is a natural product that can be isolated from fungus Aspergillus sp. Aspergillus sp metabolites has cytotoxic, antibacterial, free radical scavenging, anti-parasitic, antiviral and antiproliferative activities, etc .
|
-
- HY-W067572
-
(-)-Stobadine
|
Reactive Oxygen Species
|
Cardiovascular Disease
|
Stobadine is a potent antioxidant and prevents free radical induced alterations in ER membrane fluidity. Stobadine can be used for effective cardio- and neuroprotectants development based on antioxidant or free radical scavenging mechanisms of action .
|
-
- HY-N4084
-
|
Apoptosis
|
Cancer
|
Thonningianin A, an ellagitannin, is isolated from the methanolic extract of the African medicinal herb, Thonningia sanguinea. The antioxidant properties of Th A involve radical scavenging, anti-superoxide formation and metal chelation. Anti-cancer activities .
|
-
- HY-111898
-
|
Others
|
Cancer
|
Epirosmanol is a nature diterpene lactone from S. officinalis. Epirosmanol shows anti-cancer activity and inhibits melanin biosynthesis against melanoma cells. Epirosmanol also exhibits DPPH radical scavenging activity .
|
-
- HY-N3315
-
|
Others
|
Inflammation/Immunology
|
Massonianoside B is an antioxidant, which can be isolated from Cedrus deodara pine needle. Massonianoside B exhibits radicals scavenging capacities, and restores CCL4-impaired activity of antioxidant enzymes .
|
-
- HY-N1417
-
Sesamol
1 Publications Verification
|
|
|
Sesamol is a constituent of sesame oil. Sesamol shows a free radical scavenging activity. Sesamol shows an IC50=5.95±0.56 μg/mL in the DPPH assay. Anti-oxidant activities . Anticancer activities .
|
-
- HY-W001542
-
-
- HY-N1521
-
Lantadene A
|
Others
|
Inflammation/Immunology
|
Rehmannic acid (lantadene A) is a compound isolated from Lantana camara. Rehmannic acid shows considerable in vitro antioxidant, free radical scavenging capacity activities in a dose dependant manner. Rehmannic acid is a promising candidate for use as an antioxidant and hepatoprotective agent .
|
-
- HY-N2307A
-
(+)-Lirinidine
|
Others
|
Cancer
|
Lirinidine ((+)-Lirinidine) is an alkaloid isolated from the leaves of L. tulipifera and has antioxidant and anticancer activities. Lirinidine exhibits medium ferric reducing power activity and minor radical scavenging activity in vitro. Lirinidine can be used for cosmetic research .
|
-
- HY-N9588
-
|
Others
|
Cancer
|
Pedaliin is a bioactive component obtained from the ethanol extract of Sesame (Sesamum indicum L.) leaves (SLs). Pedaliin shows in vitro antioxidant and anti-colon cancer efficacy with radical scavenging activity and ferric reducing antioxidant power (FRAP) .
|
-
- HY-N8254
-
|
Others
|
Others
|
Haginin A (compound 3)can be isolated from the EtOAc fraction of Lespedeza cyrtobotrya. Haginin A has radical scavenging activity with IC50 values of 9.0 μM and 37.7 μM in the ABTS system and DPPH system, respectively .
|
-
- HY-126241
-
|
Aldehyde Dehydrogenase (ALDH)
|
Inflammation/Immunology
|
RV01 is an analogue of resveratrol, inhibits DNA damage, reduces acetaldehyde dehydrogenase 2 (ALDH2) mRNA expression induced by ethanol, and exhibits hydroxyl radical scavenging activity . RV01 decreases iNOS expression, with anti-neuroinflammatory activity .
|
-
- HY-W714006
-
|
Others
|
Metabolic Disease
|
Cochliodinol (compound 1) is a metabolite derived from the Apis mellifera ligustica. Cochliodinol has strong free radical scavenging activity of 2, 2-diphenyl-1-picrohydrazine (DPPH) (IC50=3.06 μg/mL) .
|
-
- HY-N0513
-
|
Others
|
Cardiovascular Disease
Inflammation/Immunology
|
Loganic acid is an iridoid isolated from cornelian cherry fruits. Loganic acid can modulate diet-induced atherosclerosis and redox status. Loganic acid has strong free radical scavenging activity and remarkable cyto-protective effect against heavy metal mediated toxicity .
|
-
- HY-N3451
-
|
Lipoxygenase
|
Cancer
|
Isothymusin is a potent anti-oxidant agent. Isothymusin shows radical scavenging activities. Isothymusin shows anti-proliferative activities in cancer cell lines. Isothymusin inhibited the enzymes associated with the promotion stage of cancer, including cycloxygenase- 2 and lipoxygenase-5 .
|
-
- HY-N8375
-
|
Others
|
Metabolic Disease
|
Sieboldin is a dihydrochalcone, which inhibits the production of advanced glycation end products (AGE) produced by bovine serum albumins (BSA), has free radical scavenging activity and cytotoxicity in cancer cell lines, and is also used to capture of methylglyoxal (MGO) from Malus baccata .
|
-
- HY-N10294
-
|
HIV
|
Infection
Inflammation/Immunology
|
Epicoccone B, firstly reported from C. globosum, exhibits the DPPH free radical scavenging ability with IC50 value of 10.8 μM, and has potent α-glucosidase inhibition with IC50 value of 27.3 μM. Anti-HIV activity .
|
-
- HY-N0393
-
|
PPAR
Reactive Oxygen Species
Bacterial
|
Infection
Inflammation/Immunology
Cancer
|
Glabridin is a natural isoflavan from Glycyrrhiza uralensis, binds to and activates PPARγ, with an EC50 of 6115 nM. Glabridin exhibits antioxidant, anti-bacterial, anti-nephritic, anti-diabetic, anti-fungal, antitumor, anti-inflammatory, antiosteoporotic, cardiovascular protective, neuroprotective and radical scavenging activities .
|
-
- HY-N3554
-
(+)-Catechol 7-β-D-xylopyranoside
|
Others
|
Others
|
Catechin-7-O-β-D-xylopyranoside is an antioxidant compound with strong DPPH free radical scavenging ability. Catechin-7-O-β-D-xylopyranoside can be extracted from birch inner bark and nepeta stem bark .
|
-
- HY-N11771
-
|
Others
|
Others
|
Glyurallin B is a flavonoid, that can be isolated from licorice (Glycyrrhiza inflata and Glycyrrhiza uralensis). Glyurallin B shows ABTS + radical scavenging activity and the inhibitory activity on lipid peroxidation, with EC50 values of 11.9 ± 0.58 μM and 15.3 ± 1.26 μM, respectivley .
|
-
- HY-N0539
-
|
Aldose Reductase
|
Cancer
|
Calceolarioside B is a natural product isolated from Akebia quinata leaves. Calceolarioside B exhibits significant inhibitory activity against rat lens aldose reductase (RLAR) with an IC50 of 23.99 μM. Calceolarioside B displays inhibitory effect on DPPH radical scavenging activity with an IC50 of 94.60 μM .
|
-
- HY-N1719
-
2α,3α,23-Trihydroxyolean-12-en-28-oic acid
|
|
|
Isoarjunolic acid (2α,3α,23-Trihydroxyolean-12-en-28-oic acid) is a triterpenoid, can be isolated from the stems of Cornus kousa. Isoarjunolic acid could have free radical scavenging activity and elastase inhibition activity .
|
-
- HY-N2443
-
|
Bacterial
|
Infection
Neurological Disease
|
Tribuloside is a flavonoid that can be isolated from Tribulus terrestris L . Tribuloside exhibits anti-mycobacterial activity against the non-pathogenic Mycobacterium species with a minimum inhibitory concentration (MIC) of 5.0 mg/mL. Tribuloside has 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity .
|
-
- HY-N3421
-
|
Interleukin Related
TNF Receptor
Influenza Virus
|
Infection
Inflammation/Immunology
Cancer
|
Koaburaside is a cytoprotective and anti-inflammatory natural compound. Koaburaside shows antioxidant activity with an IC50 of 9.0 μM for DPPH-free radical scavenging assay. Koaburaside inhibits histamine release and expressions of IL-6 and TNF-α in human mast cells. Koaburaside also effectively inhibits influenza A neuraminidase .
|
-
- HY-N4286
-
|
Apoptosis
|
Cancer
|
4-Methyldaphnetin is a precursor in the synthesis of derivatives of 4-methyl coumarin. 4-Methyldaphnetin has potent, selective anti-proliferative and apoptosis-inducing effects on several cancer cell lines. 4-Methyldaphnetin possesses radical scavenging property and strongly inhibits membrane lipid peroxidation .
|
-
- HY-124953
-
|
MAP3K
Apoptosis
|
Cancer
|
7,3',4'-Trihydroxyisoflavone, a major metabolite of Daidzein, is an ATP-competitive inhibitor of Cot (Tpl2/MAP3K8) and MKK4. 7,3',4'-Trihydroxyisoflavone has anticancer, anti-angiogenic, chemoprotective, and free radical scavenging activities .
|
-
- HY-P4531
-
|
Opioid Receptor
|
Neurological Disease
|
H-Ser-Tyr-OH is a dipeptide consisting of glutamic acid, glycine and histidine. H-Ser-Tyr-OH can form a copper(II) complex with copper ions to form a strong free radical scavenging activity. H-Ser-Tyr-OH also increases the intracellular uptake of the delta opioid receptor ligand deltorphin .
|
-
- HY-N3348
-
|
Fungal
|
Infection
Inflammation/Immunology
|
Lyoniside is a lignan glycoside with antioxidant, allelopathic and antifungal activities, which can be isolated from the rhizomes and stems of bilberry (Vaccinium myrtillus L.). Lyoniside exhibits radical scavenging properties with an IC50 value of 23 μg/mL in DPPH assay. Lyoniside inhibits the mycelial growth of Fusarium oxysporum and Mucor hiemalis at 50 μg/mL with inhibitory rates of 78% and 80%, respectively .
|
-
- HY-N0393R
-
|
PPAR
Reactive Oxygen Species
Bacterial
|
Infection
Inflammation/Immunology
Cancer
|
Glabridin (Standard) is the analytical standard of Glabridin. This product is intended for research and analytical applications. Glabridin is a natural isoflavan from Glycyrrhiza uralensis, binds to and activates PPARγ, with an EC50 of 6115 nM. Glabridin exhibits antioxidant, anti-bacterial, anti-nephritic, anti-diabetic, anti-fungal, antitumor, anti-inflammatory, antiosteoporotic, cardiovascular protective, neuroprotective and radical scavenging activities .
|
-
- HY-N9814
-
|
NO Synthase
|
Inflammation/Immunology
|
Shanciol B, isolated from the ethyl acetate extract of the air-dried whole plant of Pholidota imbricate Hook, inhibits nitric oxide (NO) production and 1,1-diphenyl-2-picrylhydrazil (DPPH) radical scavenging activity . Shanciol B is a microsomal prostaglandin E synthase-1 (mPGES-1) inhibitor with anti-inflammatory activity .
|
-
- HY-P1934A
-
|
Fungal
IFNAR
Reactive Oxygen Species
|
Infection
Inflammation/Immunology
Cancer
|
Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide . Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation . Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC50 of 24 µM in the DPPH assay .
|
-
- HY-150585
-
|
Amyloid-β
Cholinesterase (ChE)
Tau Protein
|
Neurological Disease
|
BuChE-IN-5 (compound 25b) is a potent BuChE inhibitor with an IC50 value of 1.94 μM. BuChE-IN-5 efficiently inhibits aggregation Aβ and tau protein in Escherichia coli. BuChE-IN-5 also has free radical scavenging capacity and antioxidant activity. BuChE-IN-5 can be used for researching Alzheimer’s disease .
|
-
- HY-N9051
-
|
Glucosidase
|
Inflammation/Immunology
Cancer
|
6-Prenylquercetin-3-Me ether is a natural product that can be extracted from G. uralensis leaves.
6-Prenylquercetin-3-Me ether has radical scavenging activity toward DPPH. 6-Prenylquercetin-3-Me ether also has inhibitory activity against α-glucosidase .
|
-
- HY-142125
-
|
Xanthine Oxidase
Reactive Oxygen Species
Apoptosis
|
Inflammation/Immunology
Cancer
|
Broussochalcone A is an antioxidant and an inhibitor of Xanthine Oxidase (IC50=2.21 μM), with free radical scavenging activity. Broussochalcone A inhibits iron-induced lipid peroxidation and nitric oxide synthesis in lipopolysaccharide (LPS) -activated macrophages. Broussochalcone A also induces Apoptosis of human renal carcinoma cells by increasing ROS levels and activating FOXO3 signaling pathways .
|
-
- HY-N6937
-
(R,R)-SDG; (R,R)-LGM2605
|
Others
|
Inflammation/Immunology
|
(R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) is the minor isomer of Secoisolariciresinol diglucoside in flaxseed. (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) possesses antioxidant and free radical scavenging activities and DNA-radioprotective properties. (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) inhibits myeloperoxidase (MPO) activity by suppressing both the peroxidase and chlorination cyclesin inflammatory cells .
|
-
- HY-112053
-
2,2-Diphenyl-1-picrylhydrazyl
|
Others
|
Metabolic Disease
|
DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that can be used to measure the radical scavenging activity of antioxidants. The odd electron of nitrogen atom in DPPH is reduced by receiving a hydrogen atom from antioxidants to the corresponding hydrazine. DPPH method may be utilized in aqueous and nonpolar organic solvents and can be used to examine both hydrophilic and lipophilic antioxidants .
|
-
- HY-N0403
-
|
Apoptosis
|
Inflammation/Immunology
|
2,3,4',5-Tetrahydroxystilbene 2-O-β-D-glucoside (TSG) is an active product that can be extracted from Polygonum multiflorum Thunb. TSG has anti-inflammatory, antioxidative, anti-atherosclerotic, anti-apoptotic, and free radical scavenging activities, TSG is also indicated to facilitate long-term potentiation and learning and memory in both normal and pathological conditions .
|
-
- HY-N10927
-
|
Others
|
Others
|
2,11,12-Trihydroxy-7,20-epoxy-8,11,13-abietatriene, a diterpenoid, has significant effects on DPPH radical scavenging activity with an IC50 value of 20.0 µM. 2,11,12-Trihydroxy-7,20-epoxy-8,11,13-abietatriene shows potent antioxidant activity .
|
-
- HY-W018643
-
Methyl ferulate
|
p38 MAPK
Autophagy
|
Neurological Disease
Inflammation/Immunology
Cancer
|
Ferulic acid methyl ester (Methyl ferulate) is a derivative of ferulic acid, isolated from Stemona tuberosa, with anti-inflammatory and antioxidant properties . Ferulic acid methyl ester is a cell membrane and brain permeable compound, shows free radical scavenging ability, used in the research of neurodegenerative disorders . Ferulic acid methyl ester inhibits COX-2 expression, blocks p-p38 and p-JNK in primary bone marrow derived-macrophages .
|
-
- HY-N0241
-
|
Cholinesterase (ChE)
|
Metabolic Disease
|
Rhodionin, isolated from the root of Rhodiola crenulata, is a specific non-competitive cytochrome P450 2D6 inhibitor with an IC50 of 0.761 μM and a Ki of 0.769 μM . Rhodionin exhibits potent, dose-dependent inhibitory effects on acetylcholinesterase (AChE) with IC50 ranged from 57.50 to 2.43 μg/mL . Rhodionin exhibits potent DPPH free radical scavenging activities, with an IC50 of 19.49 μM .
|
-
- HY-131803
-
|
Nucleoside Antimetabolite/Analog
|
Inflammation/Immunology
|
Urolignoside is an antioxidant with free radical scavenging activity. Urolignoside potently scavenges DPPH radical, and exhibits antioxidant to β-carotene-lineoleate model . 3'-Azido-3'-deoxyguanosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-N0495
-
Aloenin A
|
Beta-secretase
|
Neurological Disease
|
Aloenin (Aloenin A) is a kind of natural product, has effective clearing and free radical activity, and has moderate inhibitory activity on β-secretion (BACE) (IC50=14.95 μg/mL). Aloenin suppresses peritoneal hypertrophy in large rats and suppresses its release.
|
-
- HY-N10295
-
|
Aryl Hydrocarbon Receptor
|
Inflammation/Immunology
|
Flavipin is an aryl hydrocarbon receptor (Ahr) agonist that induces the expression of Ahr downstream genes in mouse CD4 + T cells and CD11b + macrophages. Flavipin inhibits the stabilizing function of Arid5a on Il23a 3′UTR, a newly identified target mRNA . Flavipin exhibits the DPPH free radical scavenging ability with IC50 value of 7.2 μM, and has potent α-glucosidase inhibition with IC50 value of 33.8 μM .
|
-
- HY-146172
-
|
Reactive Oxygen Species
|
Inflammation/Immunology
Cancer
|
Antioxidant agent-3 (Compound 14q), an potent antioxidant, displays potent DPPH radicals scavenging activity and ABTS + scavenging activity with IC50s of 26.58 and 30.31 μM, respectively. Antioxidant agent-3 (Compound 14q) increases reactive oxygen species (ROS), superoxide dismutase (SOD) and glutathione (GSH), and reduced lactate dehydrogenase (LDH) in H2O2-treated HepG2 cells .
|
-
- HY-N7432
-
|
Antibiotic
Bacterial
Fungal
|
Infection
|
DIMBOA, an antibiotic, has antibacterial properties and inhibits bacteria such as Staphylococcus aureus and the mycotoxin-producing fungus Fusarium graminearum (which causes scab). DIMBOA exhibits strong free radical scavenging activity and weak iron(III) ion reducing activity, and has antioxidant activity. DIMBOA inhibits the biosynthesis and accumulation of toxic trichothecenes by affecting the expression of Tri6 and Tri5. DIMBOA reduces plant susceptibility to scab. DIMBOA also exhibits cytotoxicity to plant cells, causing plasmolysis, cell collapse, and cell rupture .
|
-
- HY-149404
-
|
Reactive Oxygen Species
Tyrosinase
|
Others
|
Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) is a potent, non-competitive tyrosinase inhibitor with an IC50 value of 49.33 ± 2.64 µM and Ki value of 31.25 ± 0.25 µM. Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) have the highest radical scavenging activity to reduce the production of reactive oxygen species (ROS) with an IC50 value of 25.39 ± 0.77 µM. Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) can be used for anti-browning substances in the food and agricultural sectors .
|
-
- HY-N10621
-
|
Others
|
Cancer
|
3,5-Dimethoxy-2,7-phenanthrenediol (compound 2) is a phenanthrene compound isolated from the roots of Combretum laxum. 3,5-Dimethoxy-2,7-phenanthrenediol is cytotoxic to human cancer cell lines 786-0, MCF-7 and NCI/ADR-RES, with IC50s of 73.26 μM, 118.40 μM and 83.99 μM respectively. 3,5-Dimethoxy-2,7-phenanthrenediol also has free radical scavenging activity with an IC50 of 20.4 μM .
|
-
- HY-149008
-
|
Amylases
|
Metabolic Disease
Cancer
|
α-Amylase-IN-3 (Compound 4) is a none-competitive type of α-Amylase inhibitor with an IC50 value of 18.04 μM, which also has radical scavenging activities (DPPH and ABTS) with IC50 values of 16.04 μM (DPPH) and 16.99 μM (ABTS), respectively. α-Amylase-IN-3 has good protein–ligand interactions profile against α-Amylase. α-Amylase-IN-3 may have pharmacological activities such as anti-oxidative, anti-inflammatory inhibitory, which is helpful for the development of diabetes and oxidative stress associated disease .
|
-
- HY-Y0320
-
DMSO
|
Bacterial
Cholinesterase (ChE)
|
Infection
Inflammation/Immunology
Cancer
|
Dimethyl sulfoxide (DMSO) is an aprotic solvent that dissolves polar and non-polar compounds, including water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and can rapidly penetrate or enhance the penetration of other substances into biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity. Dimethyl sulfoxide also exhibits antifreeze and antibacterial properties . MCE provides Dimethyl sulfoxide that complies with the inspection standards (Ch.P) of Part 4 of the Chinese Pharmacopoeia (2020 Edition).
|
-
Cat. No. |
Product Name |
Type |
-
- HY-Y0320
-
DMSO
|
Co-solvents
|
Dimethyl sulfoxide (DMSO) is an aprotic solvent that dissolves polar and non-polar compounds, including water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and can rapidly penetrate or enhance the penetration of other substances into biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity. Dimethyl sulfoxide also exhibits antifreeze and antibacterial properties . MCE provides Dimethyl sulfoxide that complies with the inspection standards (Ch.P) of Part 4 of the Chinese Pharmacopoeia (2020 Edition).
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-N9413
-
L-γ-Glutamyl-(S)-Allyl-Cysteine
|
Peptides
|
Metabolic Disease
|
γ-Glutamyl-S-allylcysteine (L-γ-Glutamyl-(S)-Allyl-Cysteine) is a naturally occurring organosulfur compound found in garlic. γ-Glutamyl-S-allylcysteine has antiglycative effect and shows radical-scavenging and metal-chelating capacities .
|
-
- HY-P1512A
-
|
Peptides
|
Cancer
|
Antioxidant peptide A TFA is a short peptide, which contains alternative aromatic or sulfur-containing amino acid. The side chains of Antioxidant peptide A are believed to contribute to strong radical scavenging activities of peptides in the cancer cell .
|
-
- HY-P1512
-
|
SOD
|
Cancer
|
Antioxidant peptide A is a short peptide, which contains alternative aromatic or sulfur-containing amino acid. The side chains of Antioxidant peptide A are believed to contribute to strong radical scavenging activities of peptides in the cancer cell.
|
-
- HY-P5316
-
|
Peptides
|
Inflammation/Immunology
|
MHLWAAK is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MHLWAAK has high DPPH and ABTS radical scavenging ability. MHLWAAK protects zebrafish larvae from H2O2-induced oxidative damage .
|
-
- HY-P5317
-
|
Peptides
|
Inflammation/Immunology
|
MAQAAEYYR is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MAQAAEYYR has high DPPH and ABTS radical scavenging ability. MAQAAEYYR protects zebrafish larvae from H2O2-induced oxidative damage .
|
-
- HY-P5318
-
|
Peptides
|
Inflammation/Immunology
|
MDYYFEER is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MDYYFEER has high DPPH and ABTS radical scavenging ability. MDYYFEER protects zebrafish larvae from H2O2-induced oxidative damage .
|
-
- HY-P5316A
-
|
Peptides
|
Inflammation/Immunology
|
MHLWAAK TFA is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MHLWAAK TFA has high DPPH and ABTS radical scavenging ability. MHLWAAK TFA protects zebrafish larvae from H2O2-induced oxidative damage .
|
-
- HY-P5317A
-
|
Peptides
|
Inflammation/Immunology
|
MAQAAEYYR TFA is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MAQAAEYYR TFA has high DPPH and ABTS radical scavenging ability. MAQAAEYYR TFA protects zebrafish larvae from H2O2-induced oxidative damage .
|
-
- HY-P5318A
-
|
Peptides
|
Inflammation/Immunology
|
MDYYFEER TFA is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MDYYFEER TFA has high DPPH and ABTS radical scavenging ability. MDYYFEER TFA protects zebrafish larvae from H2O2-induced oxidative damage .
|
-
- HY-P4531
-
|
Opioid Receptor
|
Neurological Disease
|
H-Ser-Tyr-OH is a dipeptide consisting of glutamic acid, glycine and histidine. H-Ser-Tyr-OH can form a copper(II) complex with copper ions to form a strong free radical scavenging activity. H-Ser-Tyr-OH also increases the intracellular uptake of the delta opioid receptor ligand deltorphin .
|
-
- HY-P1934A
-
|
Fungal
IFNAR
Reactive Oxygen Species
|
Infection
Inflammation/Immunology
Cancer
|
Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide . Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation . Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC50 of 24 µM in the DPPH assay .
|
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-N2625A
-
-
-
- HY-N3289
-
-
-
- HY-N12291
-
-
-
- HY-N9387
-
-
-
- HY-N7155
-
-
-
- HY-N3141
-
-
-
- HY-N1354
-
-
-
- HY-N9289
-
-
-
- HY-N10770
-
|
Structural Classification
Flavonoids
Gramineae
Source classification
Plants
Other Flavonoids
Saccharum officinarum
|
Others
|
5'-Geranyl-5,7,2',4'-tetrahydroxyflavone, a phenolic compound, presents strong oxygen radical absorbance capacity (ORAC), DPPH radical-scavenging capacity, ABTS radical-scavenging capacity, ferric reducing antioxidant power (FRAP) and nitrite-scavenging capacity. 5'-Geranyl-5,7,2',4'-tetrahydroxyflavone has the potential for natural antioxidant research .
|
-
-
- HY-N9413
-
-
-
- HY-N1094
-
-
-
- HY-N10742
-
-
-
- HY-156711
-
-
-
- HY-121153
-
-
-
- HY-N8193
-
-
-
- HY-N1412
-
-
-
- HY-N3670
-
-
-
- HY-W018643A
-
-
-
- HY-N4177
-
-
-
- HY-N3858
-
-
-
- HY-N6043
-
-
-
- HY-111523
-
-
-
- HY-N8274
-
-
-
- HY-N0499A
-
-
-
- HY-N9068
-
-
-
- HY-N7931
-
-
-
- HY-N4246
-
-
-
- HY-N3985
-
-
-
- HY-133183
-
-
-
- HY-N3349A
-
-
-
- HY-N3349
-
-
-
- HY-N8169
-
-
-
- HY-W021267
-
-
-
- HY-N9447
-
-
-
- HY-N4111
-
-
-
- HY-N11469
-
-
-
- HY-N0026
-
-
-
- HY-N7518
-
-
-
- HY-N8194
-
-
-
- HY-N11552
-
-
-
- HY-N4168B
-
-
-
- HY-N7080
-
-
-
- HY-130294
-
-
-
- HY-N8846
-
-
-
- HY-N4084
-
-
-
- HY-111898
-
|
Source classification
Plants
|
Others
|
Epirosmanol is a nature diterpene lactone from S. officinalis. Epirosmanol shows anti-cancer activity and inhibits melanin biosynthesis against melanoma cells. Epirosmanol also exhibits DPPH radical scavenging activity .
|
-
-
- HY-N3315
-
-
-
- HY-W001542
-
-
-
- HY-N1521
-
-
-
- HY-N2307A
-
-
- HY-N9588
-
|
Flavonoids
Sesamum indicum Linn.
Pedaliaceae
Plants
Isoflavones
|
Others
|
Pedaliin is a bioactive component obtained from the ethanol extract of Sesame (Sesamum indicum L.) leaves (SLs). Pedaliin shows in vitro antioxidant and anti-colon cancer efficacy with radical scavenging activity and ferric reducing antioxidant power (FRAP) .
|
-
- HY-N8254
-
-
- HY-W714006
-
-
- HY-N0513
-
-
- HY-N3451
-
-
- HY-N8375
-
-
- HY-N10294
-
-
- HY-N0393
-
|
Structural Classification
Classification of Application Fields
Source classification
Plants
Infection
Flavonoids
Leguminosae
Phenols
Polyphenols
Inflammation/Immunology
Disease Research Fields
Glycyrrhiza uralensis Fisch.
Isoflavones
|
PPAR
Reactive Oxygen Species
Bacterial
|
Glabridin is a natural isoflavan from Glycyrrhiza uralensis, binds to and activates PPARγ, with an EC50 of 6115 nM. Glabridin exhibits antioxidant, anti-bacterial, anti-nephritic, anti-diabetic, anti-fungal, antitumor, anti-inflammatory, antiosteoporotic, cardiovascular protective, neuroprotective and radical scavenging activities .
|
-
- HY-N3554
-
-
- HY-N11771
-
-
- HY-N0539
-
-
- HY-N2443
-
-
- HY-N3421
-
-
- HY-N4286
-
-
- HY-N3348
-
-
- HY-N0393R
-
|
Infection
Structural Classification
Flavonoids
Classification of Application Fields
Leguminosae
Source classification
Phenols
Plants
Inflammation/Immunology
Disease Research Fields
Glycyrrhiza uralensis Fisch.
|
PPAR
Reactive Oxygen Species
Bacterial
|
Glabridin (Standard) is the analytical standard of Glabridin. This product is intended for research and analytical applications. Glabridin is a natural isoflavan from Glycyrrhiza uralensis, binds to and activates PPARγ, with an EC50 of 6115 nM. Glabridin exhibits antioxidant, anti-bacterial, anti-nephritic, anti-diabetic, anti-fungal, antitumor, anti-inflammatory, antiosteoporotic, cardiovascular protective, neuroprotective and radical scavenging activities .
|
-
- HY-N9814
-
-
- HY-P1934A
-
-
- HY-N9051
-
-
- HY-142125
-
-
- HY-N6937
-
-
- HY-N0403
-
-
- HY-N10927
-
|
Structural Classification
Terpenoids
Labiatae
Source classification
Diterpenoids
Plants
Stevia rebaudiana (Bertoni) Bertoni
|
Others
|
2,11,12-Trihydroxy-7,20-epoxy-8,11,13-abietatriene, a diterpenoid, has significant effects on DPPH radical scavenging activity with an IC50 value of 20.0 µM. 2,11,12-Trihydroxy-7,20-epoxy-8,11,13-abietatriene shows potent antioxidant activity .
|
-
- HY-W018643
-
-
- HY-N0241
-
-
- HY-N0495
-
-
- HY-N10295
-
-
- HY-N7432
-
-
- HY-N10621
-
|
Structural Classification
Combretaceae
Phenols
Polyphenols
Plants
Quisqualis indica Linn.
|
Others
|
3,5-Dimethoxy-2,7-phenanthrenediol (compound 2) is a phenanthrene compound isolated from the roots of Combretum laxum. 3,5-Dimethoxy-2,7-phenanthrenediol is cytotoxic to human cancer cell lines 786-0, MCF-7 and NCI/ADR-RES, with IC50s of 73.26 μM, 118.40 μM and 83.99 μM respectively. 3,5-Dimethoxy-2,7-phenanthrenediol also has free radical scavenging activity with an IC50 of 20.4 μM .
|
-
- HY-Y0320
-
DMSO
|
Microorganisms
Source classification
|
Bacterial
Cholinesterase (ChE)
|
Dimethyl sulfoxide (DMSO) is an aprotic solvent that dissolves polar and non-polar compounds, including water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and can rapidly penetrate or enhance the penetration of other substances into biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity. Dimethyl sulfoxide also exhibits antifreeze and antibacterial properties . MCE provides Dimethyl sulfoxide that complies with the inspection standards (Ch.P) of Part 4 of the Chinese Pharmacopoeia (2020 Edition).
|
-
Cat. No. |
Product Name |
|
Classification |
-
- HY-131803
-
|
|
Azide
|
Urolignoside is an antioxidant with free radical scavenging activity. Urolignoside potently scavenges DPPH radical, and exhibits antioxidant to β-carotene-lineoleate model . 3'-Azido-3'-deoxyguanosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
Your information is safe with us. * Required Fields.
Inquiry Information
- Product Name:
- Cat. No.:
- Quantity:
- MCE Japan Authorized Agent: