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Cat. No.: HY-N10927

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2,11,12-Trihydroxy-7,20-epoxy-8,11,13-abietatriene

2,11,12-Trihydroxy-7,20-epoxy-8,11,13-abietatriene, a diterpenoid, has significant effects on DPPH radical scavenging activity with an IC₅₀ value of 20.0 µM. 2,11,12-Trihydroxy-7,20-epoxy-8,11,13-abietatriene shows potent antioxidant activity.

For research use only. We do not sell to patients.

CAS No.: 1608462-12-9
Formula: C₂₀H₂₈O₄
Molecular Weight:332.43

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

2,11,12-Trihydroxy-7,20-epoxy-8,11,13-abietatriene Chemical Structure

CAS No.: 1608462-12-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Protocols (1)
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
BGC-823	IC₅₀	>10 μM Compound: 1	Cytotoxic activity against human BGC823 cells by MTT method Cytotoxic activity against human BGC823 cells by MTT method	[PMID: 25739048]
HCT-116	IC₅₀	>10 μM Compound: 1	Cytotoxic activity against human HCT116 cells by MTT method Cytotoxic activity against human HCT116 cells by MTT method	[PMID: 25739048]
HeLa	IC₅₀	>10 μM Compound: 1	Cytotoxic activity against human HeLa cells by MTT method Cytotoxic activity against human HeLa cells by MTT method	[PMID: 25739048]
HepG2	IC₅₀	>10 μM Compound: 1	Cytotoxic activity against human HepG2 cells by MTT method Cytotoxic activity against human HepG2 cells by MTT method	[PMID: 25739048]
NCI-H460	IC₅₀	>10 μM Compound: 1	Cytotoxic activity against human H460 cells by MTT method Cytotoxic activity against human H460 cells by MTT method	[PMID: 25739048]

Chemical Information

CAS No. 1608462-12-9
Molecular Weight 332.43
Formula C₂₀H₂₈O₄
SMILES

CC(C1=C(O)C(O)=C2[C@@]3(CO4)C[C@@H](O)CC(C)(C)[C@@H]3C[C@H]4C2=C1)C
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Bao-Bao Zhang, et al. Diterpenoids from Saliva plebeia R. Br. and Their Antioxidant and Anti-Inflammatory Activities. Molecules. 2015 Aug 14;20(8):14879-88. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

2,11,12-Trihydroxy-7,20-epoxy-8,11,13-abietatriene

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Biological Activity
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Protocols
Purity & Documentation
References

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2,11,12-Trihydroxy-7,20-epoxy-8,11,13-abietatriene

Biological Activity

Description

Cellular Effect

Chemical Information

Protocols

Purity & Documentation

References

Calculators

Help & FAQs

2,11,12-Trihydroxy-7,20-epoxy-8,11,13-abietatriene Related Classifications

HY-N10927 Related Classifications

Bioz

Keywords

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