Lyoniresinol
Based on 1 Customer Validation
Lyoniresinol is a lignan isolated from the Tarenna attenuata with antioxidant activities. Lyoniresinol has radical scavenging activities against DPPH with an IC50 of 82.4 μM.
For research use only. We do not sell to patients.
- Purity: 99.32%
- CAS No.: 14464-90-5
- Formula: C22H28O8
- Molecular Weight:420.45
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
IC50: 82.4 μM (DPPH)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
>30 μM
Compound: 15
|
Anticancer activity against human A549 cells by SRB assay
Anticancer activity against human A549 cells by SRB assay
|
[PMID: 21420296] |
| BV-2 | IC50 |
69.14 μM
Compound: 15
|
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of lipopolysaccharide induced NO production
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of lipopolysaccharide induced NO production
|
[PMID: 21420296] |
| SK-MEL-2 | IC50 |
>30 μM
Compound: 15
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Anticancer activity against human SK-MEL-2 cells by SRB assay
Anticancer activity against human SK-MEL-2 cells by SRB assay
|
[PMID: 21420296] |
| SK-OV-3 | IC50 |
>30 μM
Compound: 15
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Anticancer activity against human SKOV3 cells by SRB assay
Anticancer activity against human SKOV3 cells by SRB assay
|
[PMID: 21420296] |
| XF498 | IC50 |
7.14 μM
Compound: 15
|
Anticancer activity against human XF498 cells by SRB assay
Anticancer activity against human XF498 cells by SRB assay
|
[PMID: 21420296] |
Lyoniresinol has radical scavenging activities against DPPH with an IC50 of 82.4 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 14464-90-5
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Appearance Solid
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Molecular Weight 420.45
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Formula C22H28O8
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Color White to off-white
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SMILES
OC[C@@H]1[C@@H](C2=CC(OC)=C(O)C(OC)=C2)C3=C(OC)C(O)=C(OC)C=C3C[C@H]1CO
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 4.5 mg/mL (10.70 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (278 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3784 mL | 11.8920 mL | 23.7840 mL | 59.4601 mL |
| 5 mM | 0.4757 mL | 2.3784 mL | 4.7568 mL | 11.8920 mL | |
| 10 mM | 0.2378 mL | 1.1892 mL | 2.3784 mL | 5.9460 mL |