Betulaceae

5,8-Dihydroxy-6,7-dimethoxyflavone, isolated from aerial parts of Gnaphalium gaudichaudianum, has antitumor activity.

Santin is a flavonol isolated from Dodonaea uscosa.

Hirsutenone is an active botanical diarylheptanoid present in Alnus species and exhibits many biological activities, including anti-inflammatory, anti-tumor promoting and anti-atopic dermatitis effects. Hirsutenone attenuates adipogenesis by binding directly to PI3K and ERK1 in a non-ATP competitive manner. Hirsutenone can be used for the study of obesity.

3,4'-Dihydroxypropiophenone is a phenylpropanoid that can be isolated from the leaves of the B. platyphylla vat. latifolia and exhibits anti-aging activity.

Hazelnutin F is an indoleacetic acid glycoside found in the kernels of Corylus avellana L.. Hazelnutin F lacks significant antioxidant activity against ABTS and DPPH radicals.

(20S,24S)-20,24-Dihydroxy-3,4-secodammara-4(28),25-dien-3-oic acid is a secodammarane-type triterpenic acid that can be found in the male flowers of Alnus japonica.

2,6-Dihydroxyxanthone is a natural xanthone.

3,4'-Dihydroxypropiophenone 3-O-glucoside is a natural phenylacetylene.

9,10,18-Trihydroxystearic acid is a C18 family of hydroxy acid.

Carpinontriol A is a natural phenolic compound.

Platyphyllonol-5-O-β-D-xylopyranoside is a natural phenolic compound.

Giffonin P is a selective inhibitor targeting α-glucosidase with an IC₅₀ of 55.3 μM. Giffonin P delays carbohydrate hydrolysis and glucose absorption, exerting anti-hyperglycemic activity. Giffonin P reduces postprandial blood glucose levels and is primarily used in research on type 2 diabetes.

Betulonaldehyde is a pentacyclic triterpenoid that can be isolated from Diospyros filipendula. Betulonaldehyde has antiplasmodial activity (IC₅₀: 3.36 µg/mL). Betulonaldehyde has cytotoxic to NCI H187 lung cancer cells and non-cancerous Vero cells (IC₅₀s: 19.23 and 17.09 µg/mL, respectively). Betulonaldehyde inhibits Phorbol 12-myristate 13-acetate (HY-18739) induced inflammation in mice.

Carpinontriol B is a natural diarylheptanoid compound.

20(S),24(S)-Dihydroxydammar-25-en-3-one (compound 19) is a kind of triterpene. 20(S),24(S)-Dihydroxydammar-25-en-3-one can be isolated from the floral spikes of Betula platyphylla var. 20(S),24(S)-Dihydroxydammar-25-en-3-one has cytotoxicity against Human Cancer Cell Lines.

Centrolobol is a diarylheptane compound with antioxidant and anti-inflammatory properties, which exists in the fermented stems of Alnus sibirica. Centrolobol scavenges DPPH free radicals and inhibits the production of NO in LPS-stimulated immune cells. Centrolobol can be used in studies related to anti-inflammation and antioxidation.

Catechin-7-O-β-D-xylopyranoside is an antioxidant compound with strong DPPH free radical scavenging ability. Catechin-7-O-β-D-xylopyranoside can be extracted from birch inner bark and nepeta stem bark.

Hirsutanonol ((5S)-Hirsutanonol) is a diarylheptanoid that can be isolated from the bark of Alnus hirsute var. sibirica. Hirsutanonol inhibits cyclooxygenase-2 (COX-2) expression. Hirsutanonol has anti-filarial with an IC₅₀ value of 44.11 μg/mL for microfilariae.

(20S)-Protopanaxadiol-3-one is a natural product found in Melia azedarach and Betula pendula.

Arabidopyl alcohol is a natural product obtained from Betula pendula bark.