20(S),24(S)-Dihydroxydammar-25-en-3-one

製品番号: HY-N1683: Data Sheet 取扱説明書
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20(S),24(S)-Dihydroxydammar-25-en-3-one (compound 19) is a kind of triterpene. 20(S),24(S)-Dihydroxydammar-25-en-3-one can be isolated from the floral spikes of Betula platyphylla var. 20(S),24(S)-Dihydroxydammar-25-en-3-one has cytotoxicity against Human Cancer Cell Lines.

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20(S),24(S)-Dihydroxydammar-25-en-3-one 構造式

CAS 番号 : 75069-59-9

容量		在庫状況
MOQ		Minimum order quantity
50 mg		お問い合わせ
100 mg		お問い合わせ
250 mg		お問い合わせ
Other size		お問い合わせ

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

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純度とドキュメンテーション
参考文献
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製品説明

Cellular Effect

Cell Line	Type	Value	Description	References
COLO 205	IC₅₀	58.8 μM Compound: 19	Cytotoxicity against human COLON205 cells after 48 hrs by MTT assay Cytotoxicity against human COLON205 cells after 48 hrs by MTT assay	[PMID: 17346076]
K562	IC₅₀	40.2 μM Compound: 19	Cytotoxicity against human K562 cells after 48 hrs by MTT assay Cytotoxicity against human K562 cells after 48 hrs by MTT assay	[PMID: 17346076]
K562/Adr	IC₅₀	35.9 μM Compound: 19	Cytotoxicity against human doxorubicin-resistant K562/Adr cells after 48 hrs by MTT assay Cytotoxicity against human doxorubicin-resistant K562/Adr cells after 48 hrs by MTT assay	[PMID: 17346076]
K562/Adr	IC₅₀	50.4 μM Compound: 19	Cytotoxicity against human doxorubicin-resistant K562/Adr cells in presence of 1 uM doxorubicin after 48 hrs by MTT assay Cytotoxicity against human doxorubicin-resistant K562/Adr cells in presence of 1 uM doxorubicin after 48 hrs by MTT assay	[PMID: 17346076]
KB	IC₅₀	70.2 μM Compound: 19	Cytotoxicity against human KB cells after 48 hrs by MTT assay Cytotoxicity against human KB cells after 48 hrs by MTT assay	[PMID: 17346076]
MCF7	IC₅₀	73.1 μM Compound: 19	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 17346076]

分子量

458.72

分子式

C₃₀H₅₀O₃

CAS 番号

75069-59-9

SMILES

CC1(C)C(CC[C@]2(C)[C@@]3([H])CC[C@]4([H])[C@]([C@@](C)(O)CC[C@H](O)C(C)=C)([H])CC[C@](C)4[C@@](C)3CC[C@@]12[H])=O

Structure Classification

Initial Source

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Yoshiki Kashiwada, et al. Triterpenoids from the floral spikes of Betula platyphylla var. japonica and their reversing activity against multidrug-resistant cancer cells. J Nat Prod. 2007, 70, 4. [Content Brief]