1. Phenols
    Acids and Aldehydes
  2. Gyrophoric acid

Gyrophoric acid 

Cat. No.: HY-N3985
Handling Instructions

Gyrophoric acid is a good ultraviolet filter in lichen populations. Gyrophoric acid shows DPPH radical scavenging activity with an IC50 value of 105.75 µg/ml.

For research use only. We do not sell to patients.

Gyrophoric acid Chemical Structure

Gyrophoric acid Chemical Structure

CAS No. : 548-89-0

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Description

Gyrophoric acid is a good ultraviolet filter in lichen populations. Gyrophoric acid shows DPPH radical scavenging activity with an IC50 value of 105.75 µg/ml[1][2].

In Vitro

Gyrophoric acid (200 μM) leads to significant decrease of mitochondrial membrane potential in ovarian cancer cells A2780 after 24 h long exposure but not in HT-29 colon adenocarcinoma cells. Gyrophoric acid significantly inhibits cell growth and affects the expression of Bcl-2, Bax and Hsp70 proteins but only on higher concentration in A375 melanoma cancer cells. Gyrophoric acid treatment on HeLa cells clearly indicates ROS production and apoptosis as form of occurred cell death. Moreover, DNA damage and changing activity of stress/survival proteins as p38MAPK, Erk1/2 and Akt mediated by Gyrophoric acid treatment confirm pro-apoptotic potential[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

468.41

Formula

C₂₄H₂₀O₁₀

CAS No.
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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Gyrophoric acid
Cat. No.:
HY-N3985
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