4-(Chloromethyl)-7-hydroxycoumarin
Based on 1 Customer Validation
4-(Chloromethyl)-7-hydroxycoumarin (compound 4) is a hydroxycoumarin derivative with potent antioxidant effect and high hydroxyl radical-scavenging property. 4-(Chloromethyl)-7-hydroxycoumarin contains a methyl group and a chlorine group in the heterocyclic ring. A series of coumarins incorporating hydroxy-, chloro- and/or chloromethyl-moieties has been investigated as potent inhibitors of the zinc enzyme carbonic anhydrase, expecially tumor-associated isoforms CA IX and XII.
For research use only. We do not sell to patients.
- Purity: 98.01%
- CAS No.: 25392-41-0
- Formula: C10H7ClO3
- Molecular Weight:210.62
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 25392-41-0
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Appearance Solid
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Molecular Weight 210.62
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Formula C10H7ClO3
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Color Off-white to pink
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SMILES
O=C1OC(C=C2O)=C(C=C2)C(CCl)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (474.80 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (476 KB)
- English - EN (476 KB)
- Français - FR (476 KB)
- Deutsch - DE (476 KB)
- Norwegian - NO (476 KB)
- Español - ES (476 KB)
- Swedish - SV (476 KB)
- Italian - IT (476 KB)
- Korean - KR (476 KB)
- Portuguese - PT (476 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.7480 mL | 23.7399 mL | 47.4798 mL | 118.6994 mL |
| 5 mM | 0.9496 mL | 4.7480 mL | 9.4960 mL | 23.7399 mL | |
| 10 mM | 0.4748 mL | 2.3740 mL | 4.7480 mL | 11.8699 mL | |
| 15 mM | 0.3165 mL | 1.5827 mL | 3.1653 mL | 7.9133 mL | |
| 20 mM | 0.2374 mL | 1.1870 mL | 2.3740 mL | 5.9350 mL | |
| 25 mM | 0.1899 mL | 0.9496 mL | 1.8992 mL | 4.7480 mL | |
| 30 mM | 0.1583 mL | 0.7913 mL | 1.5827 mL | 3.9566 mL | |
| 40 mM | 0.1187 mL | 0.5935 mL | 1.1870 mL | 2.9675 mL | |
| 50 mM | 0.0950 mL | 0.4748 mL | 0.9496 mL | 2.3740 mL | |
| 60 mM | 0.0791 mL | 0.3957 mL | 0.7913 mL | 1.9783 mL | |
| 80 mM | 0.0593 mL | 0.2967 mL | 0.5935 mL | 1.4837 mL | |
| 100 mM | 0.0475 mL | 0.2374 mL | 0.4748 mL | 1.1870 mL |
4-(Chloromethyl)-7-hydroxycoumarin Related Classifications
HY-76779 Related Classifications
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