1. Apoptosis
  2. Apoptosis
  3. Thonningianin A

Thonningianin A 

Cat. No.: HY-N4084
Handling Instructions

Thonningianin A, an ellagitannin, is isolated from the methanolic extract of the African medicinal herb, Thonningia sanguinea. The antioxidant properties of Th A involve radical scavenging, anti-superoxide formation and metal chelation. Anti-cancer activities.

For research use only. We do not sell to patients.

Thonningianin A Chemical Structure

Thonningianin A Chemical Structure

CAS No. : 271579-11-4

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Description

Thonningianin A, an ellagitannin, is isolated from the methanolic extract of the African medicinal herb, Thonningia sanguinea. The antioxidant properties of Th A involve radical scavenging, anti-superoxide formation and metal chelation. Anti-cancer activities[1][2].

In Vitro

Thonningianin A effectively inhibited the proliferation of HepG-2 cells by inducing apoptosis, as evidenced by increase in the sub-G1 cell population, DNA fragmentation, and increase in the content of reactive oxygen species[2].

Molecular Weight

874.71

Formula

C₄₂H₃₄O₂₁

CAS No.

271579-11-4

SMILES

OC1=CC(C(OC[[email protected]@H]2[[email protected]@H]3[[email protected]](OC(C4=CC(O)=C(O)C(O)=C4)=O)[[email protected]@H](O)[[email protected]](OC5=CC(O)=C(C(CCC6=CC=CC=C6)=O)C(O)=C5)O2)=O)=C(C7=C(C(O3)=O)C=C(O)C(O)=C7O)C(O)=C1O

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Thonningianin AApoptosisantioxidantscavengingsuperoxidemetalchelationHepG-2sub-G1cellFe2+ionsInhibitorinhibitorinhibit

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