Koaburaside
Koaburaside is a cytoprotective and anti-inflammatory natural compound. Koaburaside shows antioxidant activity with an IC50 of 9.0 μM for DPPH-free radical scavenging assay. Koaburaside inhibits histamine release and expressions of IL-6 and TNF-α in human mast cells. Koaburaside also effectively inhibits influenza A neuraminidase.
For research use only. We do not sell to patients.
- CAS No.: 41653-73-0
- Formula: C14H20O9
- Molecular Weight:332.30
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A2780 | IC50 |
>10 μg/mL
Compound: page 1629, R23C1
|
Cytotoxicity against human A2780 cells after 96 hrs by MTT assay
Cytotoxicity against human A2780 cells after 96 hrs by MTT assay
|
[PMID: 17125236] |
| A549 | IC50 |
>10 μg/mL
Compound: page 1629, R23C1
|
Cytotoxicity against human A549 cells after 96 hrs by MTT assay
Cytotoxicity against human A549 cells after 96 hrs by MTT assay
|
[PMID: 17125236] |
| Bel-7402 | IC50 |
>10 μg/mL
Compound: page 1629, R23C1
|
Cytotoxicity against human Bel-7402 cells after 96 hrs by MTT assay
Cytotoxicity against human Bel-7402 cells after 96 hrs by MTT assay
|
[PMID: 17125236] |
| BGC-823 | IC50 |
>10 μg/mL
Compound: page 1629, R23C1
|
Cytotoxicity against human BGC-823 cells after 96 hrs by MTT assay
Cytotoxicity against human BGC-823 cells after 96 hrs by MTT assay
|
[PMID: 17125236] |
| HCT-8 | IC50 |
>10 μg/mL
Compound: page 1629, R23C1
|
Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay
Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay
|
[PMID: 17125236] |
Chemical Information
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CAS No. 41653-73-0
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Molecular Weight 332.30
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Formula C14H20O9
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SMILES
COC1=C(O)C(OC)=CC(O[C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)CO)=C1
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. He Y, et al. Phenolic compounds from Eurycorymbus cavaleriei. J Asian Nat Prod Res. 2011 Jun;13(6):575-80. [Content Brief]
[2]. Subedi L, et al. Anti-neuroinflammatory and neuroprotective effects of the Lindera neesiana fruit in vitro. Phytomedicine. 2016 Jul 15;23(8):872-81. [Content Brief]
[3]. Choi HG, et al. Phenolic glycosides from Lindera obtusiloba and their anti-allergic inflammatory activities. Nat Prod Commun. 2013 Feb;8(2):181-2. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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