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Results for "

C20

" in MedChemExpress (MCE) Product Catalog:

82

Inhibitors & Agonists

2

Biochemical Assay Reagents

28

Peptides

14

Natural
Products

20

Recombinant Proteins

4

Isotope-Labeled Compounds

43

Antibodies

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P10798

    LY-3841136

    Amylin Receptor Metabolic Disease
    Eloralintide is an amylin receptor (AMYR) activator and long-acting peptide. Eloralintide selectively activates amylin receptors. Eloralintide is modified with a C20 fatty diacid moiety that binds to amylin receptors while retaining selectivity from calcitonin receptors. Eloralintide induces decreased appetite.Eloralintide reduces body weight. Eloralintide can be used for the research of obesity .
    Eloralintide
  • HY-P3506
    Retatrutide
    3 Publications Verification

    LY3437943

    GCGR GLP Receptor Metabolic Disease
    Retatrutide (LY3437943) is a triple agonist peptide of the glucagon receptor (GCGR), glucosedependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide binds human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively. Retatrutide can be used for the research of obesity .
    Retatrutide
  • HY-112016

    C20 Ceramide; N-Arachidoyl-D-sphingosine

    Endogenous Metabolite Neurological Disease
    C20 Ceramide (d18:1/20:0) (N-Arachidoyl-D-sphingosine) is a natural 20:0 ceramide and a N-acylsphingosine in which the ceramide N-acyl group is specified as eicosanoyl. C20 Ceramide (d18:1/20:0) acts as a key signal molecule mediating biological processes .
    C20 Ceramide (d18:1/20:0)
  • HY-P10798A

    LY-3841136 sodium

    Amylin Receptor Calcium Channel Metabolic Disease
    Eloralintide sodium is an Amylin Receptor agonist. Eloralintide sodium selectively activates AMY1R and AMY3R in cells expressing human or rat AMY1R, AMY3R or CTR. Eloralintide sodium activates AMYRs and CTR in rats, inducing a sustained decrease in plasma Ca 2+ levels. Eloralintide sodium reduces appetite and body weight in both lean and obese rats. Eloralintide sodium can be used for research related to obesity .
    Eloralintide sodium
  • HY-19796
    Icomidocholic acid
    1 Publications Verification

    Aramchol; C20-FABAC

    Stearoyl-CoA Desaturase (SCD) Metabolic Disease
    Icomidocholic acid (Aramchol) is a lipid molecule synthesized from cholic acid and arachidic acid. Icomidocholic acid is an orally active SCD1 inhibitor and cholesterol solubilizer with antifibrotic effects. Icomidocholic acid can reduce liver fat content, dissolve cholesterol crystals and prevent gallstone formation. Icomidocholic acid can be used in the study of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) .
    Icomidocholic acid
  • HY-P3506A
    Retatrutide TFA
    3 Publications Verification

    LY3437943 TFA

    GLP Receptor GCGR Metabolic Disease
    Retatrutide (LY3437943) TFA is a triple agonist peptide of the glucagon receptor (GCGR), glucosedependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide TFA binds human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively. Retatrutide TFA can be used for the research of obesity .
    Retatrutide TFA
  • HY-P11245A

    Amylin Receptor Metabolic Disease
    NN1213 acetate, a long-acting human amylin peptide analog, is a selective Amylin receptor agonist with EC50 values of 0.177 and 0.262 nM for hAMY3R and rAMY3R, respectively. NN1213 acetate significantly reduces food intake and fat mass. NN1213 acetate can reduce body weightin diet-induced obese rats. NN1213 acetate can be used for the research of obesity .
    NN1213 acetate
  • HY-P4070

    Insulin Receptor Metabolic Disease
    Insulin icodec is an Insulin (HY-P0035) analog that strongly but reversibly binds to albumin. Insulin icodec has long plasma half-life. Insulin icodec modulates insulin receptor activity, controls blood glucose levels, reduces HbA1c levels, and binds reversibly to human serum albumin. Insulin icodec can be used for the research of type 2 diabetes mellitus .
    Insulin icodec
  • HY-158790

    Ferroptosis Cancer
    (R)-HTS-3 is an lysophosphatidylcholine acyltransferase 3 (LPCAT3) inhibitor, with an IC50 of 0.09 μM. (R)-HTS-3 suppresses the C20:4 content of PE, PC, and PS, while promoting a correspondingelevation in C22:4 phospholipids and a paradoxical increase in C20:4 phosphatidylinositol (PI) lipids .
    (R)-HTS-3
  • HY-P10956

    LY3541105

    Amylin Receptor CGRP Receptor Metabolic Disease
    Colulintide (LY3541105) is an amylin-calcitonin dual receptor agonist with Amylin as its scaffold. Colulintide is applicable to research related to type 2 diabetes and obesity .
    Colulintide
  • HY-P10959

    LY3532226

    Insulin Receptor Metabolic Disease
    Macupatide is a glucose-dependent insulinotropic polypeptide (GIP) receptor agonist. Macupatide improves insulin secretion responses and insulin sensitivity.Macupatide can be used for the research of type 2 diabetes .
    Macupatide
  • HY-N15905

    Biochemical Assay Reagents Others
    C20 Glucosyl(β) ceramide (d18:1/20:0) is a β-glucosyl ceramide.
    C20 Glucosyl(β) ceramide (d18:1/20:0)
  • HY-N15809

    Biochemical Assay Reagents Inflammation/Immunology
    C20 Galactosyl(?) ceramide (d18:1/20:0) is a β-Glucosyl ceramide.
    C20 Galactosyl(ß) ceramide (d18:1/20:0)
  • HY-P11271

    Insulin Receptor GLP Receptor Metabolic Disease
    Ribupatide is a dual gastric inhibitory polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) receptor agonist. Enicepatide can be studied in antidiabetic research .
    Ribupatide
  • HY-P11245

    Amylin Receptor Metabolic Disease
    NN1213, a long-acting human amylin peptide analog, is a selective Amylin receptor agonist with EC50 values of 0.177 and 0.262 nM for hAMY3R and rAMY3R, respectively. NN1213 significantly reduces food intake and fat mass. NN1213 can reduce body weightin diet-induced obese rats. NN1213 can be used for the research of obesity .
    NN1213
  • HY-P11285A

    Long acting GIPRA-1 TFA

    Insulin Receptor Metabolic Disease
    LAGIPRA peptide TFA is a long-acting GIP1R agonist. LAGIPRA peptide TFA enhances insulin sensitivity by augmenting glucose disposal and reduces branched-chain amino acids (BCAAs) and ketoacids. LAGIPRA peptide TFA has the potential for the research of type 2 diabetes .
    LAGIPRA peptide TFA
  • HY-W414466

    D-Erythro-sphinganine C20 chain

    Biochemical Assay Reagents Metabolic Disease
    C20-Dihydrosphingosine (D-Erythro-sphinganine C20 chain) is an ester product.
    C20-Dihydrosphingosine
  • HY-N15352

    Liposome Neurological Disease
    C20 Sphingomyelin (d18:1/20:1) is a sphingomyelin substance. The level of C20 Sphingomyelin (d18:1/20:1) is associated with amyotrophic lateral sclerosis and primary lateral sclerosis .
    C20 Sphingomyelin (d18:1/20:1)
  • HY-149526

    Cyclic GMP-AMP Synthase Infection Inflammation/Immunology
    cGAS-IN-1 (Compound C20) is a cyclic GMP-AMP synthase (cGAS) inhibitor with IC50s of 2.28 μM (human cGAS, h-cGAS FL) and 1.44 μM (mouse cGAS, m-cGAS CD). cGAS-IN-1 can be used for the studies of autoimmune diseases and chronic inflammation .
    cGAS-IN-1
  • HY-136190

    TRP Channel Neurological Disease
    TRPC6-PAM-C20 is a selective positive allosteric modulator (PAM) of TRPC6 channels. TRPC6-PAM-C20 is a potent enhancer of channel activation, enabling low basal concentrations of DAG to induce activation of the ion channel. TRPC6-PAM-C20 induces increases in intracellular Ca 2+ concentrations ([Ca 2+]i) in TRPC6-expressing HEK293 cells with an EC50 of 2.37 μM. TRPC6-PAM-C20 can be used as a valuable tool to selectively exaggerate TRPC6-dependent signals .
    TRPC6-PAM-C20
  • HY-151595

    Epigenetic Reader Domain Cancer
    Menin-MLL inhibitor-22 (compound C20) is an orally active inhibitor of the interaction between menin and mixed lineage leukemia (MLL) (IC50=7 nM). Menin-MLL inhibitor-22 binds menin protein and inhibits cancer cell growth (MV4 cells, IC50=0.3 μM). Menin is a putative tumor suppressor associated with multiple endocrine neoplasia type 1 (MEN-1 syndrome) .
    Menin-MLL inhibitor-22
  • HY-112016A

    (E/Z)-C20 Ceramide; (E/Z)-N-Arachidoyl-D-sphingosine

    Endogenous Metabolite Neurological Disease
    (E/Z)-C20 Ceramide (d18:1/20:0) ((E/Z)-N-Arachidoyl-D-sphingosine) is the mixture of (Z)-C20 Ceramide and (E)-C20 Ceramide .
    (E/Z)-C20 Ceramide (d18:1/20:0)
  • HY-134104

    D-erythro-Sphingosine-C20

    Others Neurological Disease
    C20-Sphingosine is a long-chain base (LCB) that can be used in the study of neural development .
    C20-Sphingosine
  • HY-P11285

    Long acting GIPRA-1

    Insulin Receptor Metabolic Disease
    LAGIPRA peptide is a long-acting GIP1R agonist. LAGIPRA peptide enhances insulin sensitivity by augmenting glucose disposal and reduces branched-chain amino acids (BCAAs) and ketoacids. LAGIPRA peptide has the potential for the research of type 2 diabetes .
    LAGIPRA peptide
  • HY-N16008

    Biochemical Assay Reagents Others
    C20:4 Anandamide (AEA) is a class of anandamides.
    C20:4 Anandamide (AEA)
  • HY-P10959A

    LY3532226 acetate

    Insulin Receptor Metabolic Disease
    Macupatide acetate is a glucose-dependent insulinotropic polypeptide (GIP) receptor agonist. Macupatide acetate improves insulin secretion responses and insulin sensitivity.Macupatide acetate can be used for the research of type 2 diabetes .
    Macupatide acetate
  • HY-17649

    Progesterone Receptor Neurological Disease
    EIDD-036, is the blood-brain barrier penetrant C-20 oxime of Progesterone (HY-N0437), that binds progesterone receptor (PR) with an IC50 of 171 nM. EIDD-036 is the active metabolite of EIDD-1723 (HY-125547). EIDD-036 exhibits promising challenges for rapid administration in acute trauma. EIDD-036 can be used for the study of traumatic brain injury (TBI) .
    EIDD-036
  • HY-W590670

    N-[(2S,3R)-1,3-Dihydroxyoctadecan-2-yl]icosanamide

    Biochemical Assay Reagents Others
    C20-Dihydroceramide is a biochemical assay reagent.
    C20-Dihydroceramide
  • HY-113445

    COX Endogenous Metabolite Endocrinology
    Thromboxane B3 is a prostaglandin analog derived from arachidonic acid (AA) in the cyclooxygenase (COX) metabolic pathway. Thromboxane B3 is generated from arachidonic acid (AA) in platelets and vascular endothelial cells through the catalysis of cyclooxygenase (COX) and thromboxane synthase (TXS). Thromboxane B3 has been reported to be formed by human platelets upon ingestion of eicosapentaenoic acid (C20: 5ω3) .
    Thromboxane B3
  • HY-117580

    OH-PRED

    Drug Metabolite Inflammation/Immunology
    16α-Hydroxyprednisolone (OH-PRED) is a stereoselective metabolite of the 22(R) epimer of the glucocorticoid Budesonide (HY-13580). 16α-Hydroxyprednisolone formation is catalyzed by isoenzymes within the cytochrome P450 3A (CYP3A) subfamily. 16α-Hydroxyprednisolone formation can be inhibited by antibodies targeting the CYP3A subfamily .
    16α-Hydroxyprednisolone
  • HY-145549

    N-eicosanoyl-D-erythro-Sphingosylphosphorylcholine; SM(d18:1/20:0)

    Endogenous Metabolite Endocrinology
    C20 Sphingomyelin (d18:1/20:0) (N-eicosanoyl-D-erythro-Sphingosylphosphorylcholine; SM(d18:1/20:0)) is a naturally occurring sphingolipid. C20 Sphingomyelin (d18:1/20:0) levels are upregulated in the hippocampus of streptozotocin (HY-13753)-induced diabetic rats and in human plasma, positively correlating with insulin resistance in obese humans. C20 Sphingomyelin (d18:1/20:0) is also upregulated in the liver of a mouse model of Niemann-Pick C1 disease, a neurodegenerative cholesterol sphingolipid lysosomal storage disorder.
    C20 Sphingomyelin (d18:1/20:0)
  • HY-164412

    Endogenous Metabolite LDLR Others
    Phosphatidylcholine (C18:2,C20:4) is a phospholipid that can be isolated from egg yolk .
    Phosphatidylcholine (C18:2,C20:4)
  • HY-P11271A

    Insulin Receptor GLP Receptor Metabolic Disease
    Ribupatide TFA is a dual gastric inhibitory polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) receptor agonist. Ribupatide TFA can be studied in antidiabetic research .
    Ribupatide TFA
  • HY-P3506B

    LY3437943 acetate

    GCGR GLP Receptor Metabolic Disease
    Retatrutide (LY3437943) acetate is a triple agonist peptide of the glucagon receptor (GCGR), glucosedependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide acetate inhibits human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively. Retatrutide acetate can be used for the research of obesity .
    Retatrutide acetate
  • HY-P10591

    Olatorepatidum

    Insulin Receptor GLP Receptor Metabolic Disease
    Olatorepatide (Olatorepatidum) is a dual gastric inhibitory polypeptide (GIP) receptor and glucagon like peptide 1 (GLP-1) receptor agonist, with antidiabetic effect .
    Olatorepatide
  • HY-N10703

    Others Others
    2-Isopropyl-8,8-dimethyl-7,8-dihydrophenanthrene-3,4,5(6H)-trione is a C20 -norabietane diterpenoid with anti-inflammatory activity. 2-Isopropyl-8,8-dimethyl-7,8-dihydrophenanthrene-3,4,5(6H)-trione can be isolated from sage leaves .
    1-Oxomiltirone
  • HY-158801

    C20:4 Carnitine chloride; L-Arachidonoylcarnitine chloride; L-Carnitine arachidonoyl ester chloride

    Endogenous Metabolite Metabolic Disease
    Arachidonoyl-L-carnitine (C20:4 Carnitine) chloride is an arachidonic acid-L-carnitine complex .
    Arachidonoyl-L-carnitine chloride
  • HY-W746957

    Drug Intermediate Others
    GA44 is a C20-gibberellin and is an intermediate in the early 13-hydroxylation pathway .
    GA44
  • HY-179803

    Others Metabolic Disease
    C20 Ceramide (d17:1/20:0) is a ceramide.
    C20 Ceramide (d17:1/20:0)
  • HY-114668

    Camptothecin-20-O-propionate

    Topoisomerase Cancer
    Camptothecin-20(S)-O-propionate (CZ48), the C20-propionate ester of CPT, is a highly effective anticancer agent. Camptothecin-20(S)-O-propionate (CZ48) is a topoisomerase-Ι inhibitor .
    Camptothecin-20(S)-O-propionate
  • HY-146935S

    Isotope-Labeled Compounds Others
    C20:1 Ceramide-d7 is deuterium labeled C20:1 Ceramide.
    C20:1 Ceramide-d7
  • HY-P11235

    PF-08653944; MET-097

    GLP Receptor Metabolic Disease
    Berobenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist .
    Berobenatide
  • HY-P11270

    BGM0504; BG128

    Insulin Receptor GLP Receptor Metabolic Disease
    Relsipatide (BG128) is a dual gastric inhibitory polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) receptor agonist. Enicepatide can be studied in antidiabetic research .
    Relsipatide
  • HY-P11237

    CT-388

    GCGR Insulin Receptor Metabolic Disease
    Enicepatide is a dual gastric inhibitory polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) receptor agonist. Enicepatide can be studied in antidiabetic research .
    Enicepatide
  • HY-141635

    Endogenous Metabolite Metabolic Disease
    cis-11,14-Eicosadienoic acid methyl ester is a more lipid soluble form of the ω-6 C20-2 fatty acid 11(Z),14(Z)-eicosadienoic acid, a naturally occurring PUFA. 11(Z),14(Z)-Eicosadienoic acid competitively inhibits inosine 5’-monophosphate dehydrogenase (Ki=3.1 μM) and inhibits the binding of LTB4 to its receptor on neutrophils (Ki=3.0 μM). Also, serum levels of eicosadienoic acids negatively correlate with degree of sleep disturbance.3 Eicosadienoic acids are converted by desaturases, in vivo, to eicosatrienoic acids, which are potent vasodilators.
    cis-11,14-Eicosadienoic acid methyl ester
  • HY-139062

    C6 Ceramide (d18:1/6:0) Urea; Cer(d18:1/6:0) Urea; D-erythro-Urea-C6-Ceramide

    Apoptosis Ceramidase Autophagy β-catenin Cancer
    C6 Urea Ceramide (Cer(d18:1/6:0) Urea) is an inhibitor of neutral ceramidase. C6 Urea Ceramide increases total ceramide levels in wild-type mouse embryonic fibroblasts (MEFs) and HT-29 colon cancer cells. C6 Urea Ceramide (5-10 μM) inhibits proliferation of HT-29 cells and induces apoptosis and autophagy, but is not toxic to non-cancerous cells. C6 Urea Ceramide decreases total and phosphorylated β-catenin levels in HT-29 and HCT116 cells, and induces colocalization of β-catenin with the 20S proteasome. C6 Urea Ceramide (1.25, 2.5, and 5 mg/kg) reduced tumor growth and increased C16, C18, C20, and C24 ceramide levels in tumor tissues in the HT-29 mouse xenograft model.
    C6 Urea Ceramide
  • HY-CE00116

    C20:3(Omega-3)-CoA; Cis-(omega-3)-icosatrienoyl-CoA

    Biochemical Assay Reagents Others
    (11Z,14Z,17Z)-Icosatrienoyl-CoA (C20:3(Omega-3)-CoA) is an unsaturated fatty acyl-CoA.
    (11Z,14Z,17Z)-Icosatrienoyl-CoA
  • HY-N11436

    Others Others
    Aconicarchamine B is a C20-diterpenoid alkaloid, which can be isolated from Aconitum carmichaelii .
    Aconicarchamine B
  • HY-163635

    Fungal Infection
    Antifungal agent 102 (compound C20) is a antifungal agent aganist B. cinerea with the EC50 of 1.23 μg/mL .
    Antifungal agent 102
  • HY-W127464

    Biochemical Assay Reagents Others
    Arachidyl Laurate is a laurate medium chain saturated (C20:0) fatty acid ester compound that can be used as a reference for the analysis of wax laurate.
    Arachidyl Laurate

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