Gibberellin A12
Gibberellin A12 is a free C20-gibberellin, serving as a gibberellin biosynthesis intermediate and metabolite precursor. Gibberellin A12 exists in maturing Sechium edule seed testa, developing Pisum sativum seeds and Gibberella fujikuroi.
For research use only. We do not sell to patients.
- CAS No.: 1164-45-0
- Formula: C20H28O4
- Molecular Weight:332.43
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Gibberellin A12 is present as a free compound in the testa of maturing Sechium edule seeds, and is absent from the embryo and endosperm of these seeds[1].
Gibberellin A12 (0.064-1.0 mM MVA; 2-4 h) is synthesized from MVA by cell-free extracts from Cucurbita maxima liquid endosperm with an apparent Km of 0.4 mM MVA, achieving up to 7% incorporation of MVA into GA12[2].
Gibberellin A12 exists in developing Pisum sativum L. seeds, and can be enzymatically synthesized from mevalonic acid with definite specific activity and production efficiency[3].
Gibberellin A12 (0.2 μCi; 1-24 h) is rapidly and exclusively metabolized by cotyledons from 20-day-old Pisum sativum L. G2 seeds to 13-hydroxylated gibberellins[4].
Gibberellin A12 (0.2 μCi; 3-24 h) is slowly metabolized by seed coats from 20-day-old Pisum sativum L. G2 seeds to both 13-hydroxylated and non-13-hydroxylated gibberellins[4].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1164-45-0
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Appearance Solid
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Molecular Weight 332.43
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Formula C20H28O4
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SMILES
OC([C@@H]1[C@]23[C@](CC[C@](C(C3)=C)([H])C2)([H])[C@]4([C@@]1([H])[C@@](C)(CCC4)C(O)=O)C)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
References
[1]. Albone KS, et al. Identification and localization of gibberellins in maturing seeds of the cucurbit Sechium edule, and a comparison between this cucurbit and the legume Phaseolus coccineus. Planta. 1984;162(6):560-565. [Content Brief]
[2]. Birnberg PR, et al. An improved enzymatic synthesis of labeled gibberellin A12-aldehyde and gibberellin A12. Anal Biochem. 1986;153(1):1-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)