1. Membrane Transporter/Ion Channel Neuronal Signaling Metabolic Enzyme/Protease
  2. TRP Channel FAAH
  3. 20-Hydroxy-N-arachidonoyl taurine

20-Hydroxy-N-arachidonoyl taurine (Compound C20:4 NAT) acts as an activator of TRPV1 and TRPV4, with EC50 values of 28 µM and 21 µM, respectively. 20-Hydroxy-N-arachidonoyl taurine serves as a substrate for fatty acid amide hydrolase (FAAH).

For research use only. We do not sell to patients.

20-Hydroxy-N-arachidonoyl taurine

20-Hydroxy-N-arachidonoyl taurine Chemical Structure

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Description

20-Hydroxy-N-arachidonoyl taurine (Compound C20:4 NAT) acts as an activator of TRPV1 and TRPV4, with EC50 values of 28 µM and 21 µM, respectively. 20-Hydroxy-N-arachidonoyl taurine serves as a substrate for fatty acid amide hydrolase (FAAH)[1].

IC50 & Target[1]

TRPV1

 

TRPV4

 

In Vitro

20-Hydroxy-N-arachidonoyl taurine (20 µM; concentration-dependence profiling) activates TRPV1-transfected CHO cells with an EC50 of 28 µM and TRPV4-transfected CHO cells with an EC50 of 21 µM, but does not activate TRPM8-transfected CHO cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

427.60

Formula

C22H37NO5S

SMILES

O=C(NCCS(=O)(O)=O)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCCO

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
20-Hydroxy-N-arachidonoyl taurine
Cat. No.:
HY-181463
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