MAO-B-IN-50
MAO-B-IN-50 (Compound C20) is a selective MAO-B inhibitor with an IC50 value of 0.06 μM. MAO-B-IN-50 shows good inhibitory effects on the aggregation of Aβ40/42 and Tau proteins, with overall IC50 values around 1 μM. MAO-B-IN-50 exhibits potent and selective AChE inhibition (IC50 = 1.78 μM). MAO-B-IN-50 can be used in the research of Alzheimer's disease.
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- CAS No.: 3105860-84-9
- Formule: C28H24N2O8
- Masse moléculaire:516.50
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
IC50 & Target
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MAO-B 0.06 μM (IC50) |
MAO-A 0.98 μM (IC50) |
AChE 1.78 μM (IC50) |
Chemical Information
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CAS No. 3105860-84-9
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Masse moléculaire 516.50
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Formule C28H24N2O8
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SMILES
O=C1/C(C(OC)OC2=C1C=C(O)C=C2)=C\NC3=CC=C(N/C=C4C(OC)OC5=C(C=C(O)C=C5)C\4=O)C=C3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Alzheimer’s Disease Modeling
Alzheimer’s Disease (AD) is a neurodegenerative disorder characterized by a progressive decline in cognitive functions and loss of specific types of neurons and synapses. Alzheimer's symptoms can be simulated in mice by injecting drugs (such as Aβ) or genetically modified.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MAO-B-IN-50 Related Classifications
HY-180842 Related Classifications
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