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Cat. No.: HY-128395

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C20-Dihydrosphingomyelin

(Synonyms: C20-DHSM; DHSM (d18:0/20:0))

C20-Dihydrosphingomyelin (C20-DHSM; DHSM (d18:0/20:0)) is a saturated form of Sphingomyelin (HY-113498). C20-Dihydrosphingomyelin is a secondary component of most cell sphingolipids and its levels significantly decrease after intermittent fasting during Ramadan. C20-Dihydrosphingomyelin can be used for the development of liposome reagents.

For research use only. We do not sell to patients.

CAS No.: 917104-47-3
Formula: C₄₃H₈₉N₂O₆P
Molecular Weight:761.15

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (262 KB)

C20-Dihydrosphingomyelin Chemical Structure

CAS No.: 917104-47-3

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Fluorescent Dye

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Biological Activity

Description

All Endogenous Metabolite Isoforms :

Chemical Information

CAS No. 917104-47-3
Molecular Weight 761.15
Formula C₄₃H₈₉N₂O₆P
SMILES

CCCCCCCCCCCCCCCCCCCC(N[C@H]([C@H](O)CCCCCCCCCCCCCCC)COP(OCC[N+](C)(C)C)([O-])=O)=O
Synonyms

C20-DHSM; DHSM (d18:0/20:0)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (262 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Madkour MI, et al. Ramadan intermittent fasting is associated with ameliorated inflammatory markers and improved plasma sphingolipids/ceramides in subjects with obesity: lipidomics analysis. Sci Rep. 2023 Oct 13;13(1):17322.

[2]. Kasagi N, et al. Optimization of dihydrosphingomyelin/cholesterol mol ratio in topotecan-loaded liposomes to enhance drug retention and plasma half-life by understanding physicochemical and thermodynamic properties of the lipid membrane. Journal of Molecular Structure. 2023 Jul 5;1283:135333.

[3]. Yano M, et al. Quantitative analysis of ceramide molecular species by high performance liquid chromatography. J Lipid Res. 1998 Oct;39(10):2091-8. PMID: 9788256. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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C20-Dihydrosphingomyelin

All Endogenous Metabolite Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

C20-Dihydrosphingomyelin Related Classifications

HY-128395 Related Classifications