1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Sphingomyelin

Sphingomyelin 

Cat. No.: HY-113498 Purity: >97.0%
Handling Instructions

Sphingomyelin is a eukaryotic sphingolipid and one of the major constituents of cell membranes and particularly abundant in the myelin sheath that surrounds neuronal axons. Sphingomyelin plays an important role in cell processes, the regulation of inflammatory responses, and signal transduction. Sphingomyelin metabolism is associated with various central nervous system diseases and Niemann–Pick disease.

For research use only. We do not sell to patients.

Sphingomyelin Chemical Structure

Sphingomyelin Chemical Structure

CAS No. : 85187-10-6

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10 mM * 1  mL in DMSO USD 169 In-stock
Estimated Time of Arrival: December 31
5 mg USD 105 In-stock
Estimated Time of Arrival: December 31
10 mg USD 170 In-stock
Estimated Time of Arrival: December 31
50 mg USD 600 Get quote
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Based on 1 publication(s) in Google Scholar

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Description

Sphingomyelin is a eukaryotic sphingolipid and one of the major constituents of cell membranes and particularly abundant in the myelin sheath that surrounds neuronal axons. Sphingomyelin plays an important role in cell processes, the regulation of inflammatory responses, and signal transduction. Sphingomyelin metabolism is associated with various central nervous system diseases and Niemann–Pick disease[1][2][3][4].

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

Sphingomyelin metabolism resulting in the production of various interconvertible bioactive sphingolipids or derivatives such as ceramide, diacylglyceride, and sphingosine-1-phosphate. These bioactive lipids act on their specific targets within the cell and regulate various signal transduction pathways, thereby affecting cellular functions[1].
Sphingomyelin enriched lipid raft mediated cell signaling[1].

Clinical Trial
Molecular Weight

732.08

Formula

C₄₁H₈₄N₂O₆P

CAS No.

85187-10-6

SMILES

[Sphingomyelin]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
  -20°C 1 month
References

Purity: >97.0%

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Keywords:

SphingomyelinEndogenous MetaboliteEukaryoticsphingolipidcellmembranesneuronalaxonssphingophospholipidsNiemann–PickdiseaseInhibitorinhibitorinhibit

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Sphingomyelin
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