85187-10-6
85187-10-6
Chemical Structure
Biological Activity: Sphingomyelin is a eukaryotic sphingolipid and one of the major constituents of cell membranes and particularly abundant in the myelin sheath that surrounds neuronal axons. Sphingomyelin plays an important role in cell processes, the regulation of inflammatory responses, and signal transduction. Sphingomyelin metabolism is associated with various central nervous system diseases and Niemann–Pick disease[1][2][3][4].
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Sphingomyelin | 98.0% | Sphingomyelin is a eukaryotic sphingolipid and one of the major constituents of cell membranes and particularly abundant in the myelin sheath that surrounds neuronal axons. Sphingomyelin plays an important role in cell processes, the regulation of inflammatory responses, and signal transduction. Sphingomyelin metabolism is associated with various central nervous system diseases and Niemann–Pick disease. | ||||||||||||||||||||
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References
- [1]. Chakraborty M, et al. Sphingomyelin and its role in cellular signaling. Adv Exp Med Biol. 2013;991:1-14. [Content Brief]
- [2]. Schneider N, et al. Sphingomyelin in Brain and Cognitive Development: Preliminary Data. eNeuro. 2019 Aug 6;6(4). pii: ENEURO.0421-18.2019. [Content Brief]
- [3]. Bienias K, et al. Regulation of sphingomyelin metabolism. Pharmacol Rep. 2016 Jun;68(3):570-81. [Content Brief]
- [4]. Schuchman EH, et al. Types A and B Niemann-Pick disease. Mol Genet Metab. 2017 Jan - Feb;120(1-2):27-33. [Content Brief]
Keywords
