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ROMO1 Antibody (YA8354)(PBS only)

(Synonyms: bA353C18.2; C20orf52; MTGM; MTGMP)

ROMO1 Antibody (YA8354) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ROMO1.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    WB, IHC-P, ICC/IF

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • ROMO1 Antibody (YA8354)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
Dilution Ratio 1:500-2000 1:150-500 1:100-250

Product Details

Description

ROMO1 Antibody (YA8354) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ROMO1.

  • Host Mouse
  • Species Reactivity
    Human
  • Calculated Molecular Weight Predicted band size: 8 kDa
Immunogen

Full length human recombinant protein of human ROMO1 produced in HEK293T cell.

Purification

Affinity purified

Conjugation

Non-conjugated

Isotype

IgG1

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    ROMO1 induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation|Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage

  • Subcellular Localization

    Mitochondrion inner membrane

  • Expression


    Tissue_Specificity: Up-regulated in a number of cancer cell lines when compared to a normal lung fibroblast cell line. Highly expressed in brain tumors
    Induction: By the anticancer drug fluorouracil (5FU)

  • Isoforms & Post-Translational Modification

    P60602 has two isomers: P60602-1: 8183 Da (predicted); P60602-2: 5900 Da (predicted).

  • SwissProt ID

    P60602

  • Synonyms

    bA353C18.2; C20orf52; MTGM; MTGMP

ROMO1 Antibody (YA8354)(PBS only) Related Classifications

MOQ
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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • ROMO1 Antibody (YA8354)(PBS only) Product Image