1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. TRP Channel
  3. TRPC6-PAM-C20

TRPC6-PAM-C20 

Cat. No.: HY-136190
Handling Instructions

TRPC6-PAM-C20 is a selective TRPC6 positive allosteric modulator. TRPC6-PAM-C20 selectively activates TRPC6 over other TRP channels and also activates TRPA1. TRPC6-PAM-C20 induces transient increase in intracellular Ca2+ in HEK cells expressing TRPC6 (EC50=2.37 μM).

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TRPC6-PAM-C20 Chemical Structure

TRPC6-PAM-C20 Chemical Structure

CAS No. : 667427-75-0

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Description

TRPC6-PAM-C20 is a selective TRPC6 positive allosteric modulator. TRPC6-PAM-C20 selectively activates TRPC6 over other TRP channels and also activates TRPA1. TRPC6-PAM-C20 induces transient increase in intracellular Ca2+ in HEK cells expressing TRPC6 (EC50=2.37 μM).

Molecular Weight

363.41

Formula

C₂₂H₂₁NO₄

CAS No.

667427-75-0

SMILES

O=C1C(C2=NC(C)(C)CC3=C2C=C(OC)C(OC)=C3)=CC4=CC=CC=C4O1

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Keywords:

TRPC6-PAM-C20TRP ChannelTransient receptor potential channelsInhibitorinhibitorinhibit

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TRPC6-PAM-C20
Cat. No.:
HY-136190
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