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ITPA Antibody (YA3104)(PBS only)

(Synonyms: My049; ITPase; NTPase; C20orf37; dJ794I6.3; HLC14-06-P)

ITPA Antibody (YA3104) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ITPA.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB, IHC-P

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • ITPA Antibody (YA3104)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Applications

Application
WB Info
WB: Western Blot
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
Dilution Ratio 1:500-1:1000 1:50-1:100

Product Details

Description

ITPA Antibody (YA3104) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ITPA.

  • Host Rabbit
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 21 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 21 kDa
Immunogen

A synthetic peptide of human Inosine triphosphate pyrophosphatase

Purification

Affinity Purified

Conjugation

Non-conjugated

Isotype

IgG

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    ITPA is a Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions

  • Subcellular Localization

    Cytoplasm

  • Expression


    Tissue_specificity:Ubiquitous. Highly expressed in heart, liver, sex glands, thyroid and adrenal gland

  • Isoforms & Post-Translational Modification

    Q9BY32 has 3 isomers: Q9BY32-1: 21446 Da (predicted); Q9BY32-2: 19603 Da (predicted); Q9BY32-3: 16833 Da (predicted).

  • Subunit

    Homodimer

  • SwissProt ID

    Q9BY32

  • Gene ID
    3704 [NCBI]
  • Synonyms

    My049; ITPase; NTPase; C20orf37; dJ794I6.3; HLC14-06-P

  • Research Field

    -

ITPA Antibody (YA3104)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • ITPA Antibody (YA3104)(PBS only) Product Image