DTD1 Antibody (YA8629)
(Synonyms: C20orf88; DUE-B; DUEB; HARS2; pqn-68)DTD1 Antibody (YA8629) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DTD1.
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Host:
Mouse
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Isotype:
IgG1
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Application:
ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
Applications
| Application |
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|
| Dilution Ratio | 1:100-250 |
Product Details
DTD1 Antibody (YA8629) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DTD1.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 23.2 kDa
Full length human recombinant protein of human DTD1 produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
DTD1 is a Possible ATPase involved in DNA replication, may facilitate loading of CDC45 onto pre-replication complexes |An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality[1][2].
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Subcellular Localization
Nucleus,Cytoplasm
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Expression
Tissue_Specificity: Expressed in many adult and fetal tissues. Highest levels in testis, ovary, spleen and in adult and fetal brain -
Isoforms & Post-Translational Modification
Q8TEA8: 209 amino acids, molecular weight 23424 Da.
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Subunit
Homodimer (PubMed:15653697)
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SwissProt ID
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Synonyms
C20orf88; DUE-B; DUEB; HARS2; pqn-68
Documentation