366 Results for "

peptide ligand

" in MedChemExpress (MCE) Product Catalog:
Products (366)

366 Results for "peptide ligand" in MCE Product Catalog:

16
16 Publications Verification
Cat. No.: HY-P0224
CAS No.: 59880-97-6
Synonyms: fMLP; N-Formyl-MLF
Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

N-Formyl-Met-Leu-Phe (fMLP; N-Formyl-MLF) is a chemotactic peptide and a specific ligand of N-formyl peptide receptor (FPR). N-Formyl-Met-Leu-Ph is reported to inhibit TNF-alpha secretion.
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9
9 Cited Publications
Cat. No.: HY-P1740
CAS No.: 114681-65-1
Target:  

Integrin Apoptosis Caspase

Research Areas:  

Inflammation/Immunology

RGD peptide (GRGDNP) is an inhibitor of integrin-ligand interactions. RGD peptide (GRGDNP) competitively inhibits α5β1 binding with extracellular matrice (ECM). RGD peptide (GRGDNP) promotes apoptosis through activation of conformation changes that enhance pro-caspase-3 activation and autoprocessing. RGD peptide (GRGDNP) plays an important role in cell adhesion, migration, growth, and differentiation .
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9
9 Cited Publications
Cat. No.: HY-P1740A
Target:  

Integrin Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

RGD peptide (GRGDNP) TFA is an inhibitor of integrin-ligand interactions. RGD peptide (GRGDNP) TFA competitively inhibits α5β1 binding with extracellular matrice (ECM). RGD peptide (GRGDNP) TFA promotes apoptosis through activation of conformation changes that enhance pro-caspase-3 activation and autoprocessing. RGD peptide (GRGDNP) TFA plays an important role in cell adhesion, migration, growth, and differentiation .
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7
7 Cited Publications
Cat. No.: HY-P7224
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL8; Lung Giant Cell Carcinoma-Derived Chemotactic Protein; Prev. IL8; Alveolar Macrophage Chemotactic Factor I; MDNCF; Tumor Necrosis Factor-Induced Gene 1; NAP-1; Neutrophil-Activating peptide 1; MONAP; T-Cell Chemotactic Factor; GCP-1; Interleukin 8; Monocyte-Derived Neutrophil Chemotactic Factor; Interleukin-8; Monocyte-Derived Neutrophil-Activating peptide; Emoctakin; Granulocyte Chemotactic Protein 1; AMCF-I; Chemokine (C-X-C Motif) ligand 8; B-ENAP; SCYB8; TSG-1; LYNAP; 3-10C; LUCT; K60; LECT; Small Inducible Cytokine Subfamily B, Member 8; IL-8; Beta-Thromboglobulin-Like Protein; GCP1; Neutrophil-Activating Protein 1; NAP1; C-X-C Motif Chemokine 8; NAF; C-X-C Motif Chemokine; Beta Endothelial Cell-Derived Neutrophil Activating peptide; Protein 3-10C; C-X-C Motif Chemokine ligand 8; Lymphocyte Derived Neutrophil Activating peptide
Species:  
Human
Source:  
E. coli
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5
5 Cited Publications
Cat. No.: HY-P2268
CAS No.: 1092460-91-7
Target:  

Amyloid-β

Research Areas:  

Inflammation/Immunology Cancer

RAGE antagonist peptide is an advanced glycation end products (RAGE) antagonist. RAGE antagonist peptide prevents RAGE from binding with several of its most important ligands, including HMGB-1, S100P, and S100A4. RAGE antagonist peptide (RAP) possesses anti-tumor and anti-inflammatory activities .
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5
5 Cited Publications
Cat. No.: HY-P2268A
Target:  

Amyloid-β

Research Areas:  

Inflammation/Immunology Cancer

RAGE antagonist peptide TFA is an advanced glycation end products (RAGE) antagonist. RAGE antagonist peptide TFA prevents RAGE from binding with several of its most important ligands, including HMGB-1, S100P, and S100A4. RAGE antagonist peptide TFA possesses anti-tumor and anti-inflammatory activities .
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5
5 Cited Publications
Cat. No.: HY-10199A
CAS No.: 159634-47-6
Purity:  98.52%
Synonyms: MK-677 free base; MK-0677 free base
Ibutamoren (MK-677 free base; MK-0677 free base) is an orally active non-peptide growth hormone secretagogue receptor agonist. Ibutamoren activates signal cascades by mimicking endogenous ligands, triggers pulsatile release of growth hormone from the pituitary gland, and increases serum levels of IGF-1 and insulin-like growth factor-binding protein 3. Ibutamoren not only increases the frequency of growth hormone pulses in male individuals, but also promotes elevated bone formation markers in female individuals with postmenopausal osteoporosis. The combination of Ibutamoren with Alendronate sodium hydrate (HY-11101) significantly increases bone mineral density at the femoral neck. However, Ibutamoren may cause mild, reversible adverse reactions such as increased appetite, fluid retention, and elevated fasting blood glucose. Ibutamoren has been widely used in studies related to idiopathic growth hormone deficiency, sarcopenia, Alzheimer's disease, and osteoporosis .
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3
3 Cited Publications
Cat. No.: HY-P1868
CAS No.: 134580-64-6
Synonyms: DGEA peptide
Target:  

Integrin

Research Areas:  

Infection

α2β1 Integrin Ligand Peptide interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular signals into cells. It is a potential antagonist of collagen receptors .
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3
3 Cited Publications
Cat. No.: HY-P1868A
Synonyms: DGEA peptide TFA
Target:  

Integrin

Research Areas:  

Others

α2β1 Integrin Ligand Peptide TFA interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular signals into cells. It is a potential antagonist of collagen receptors .
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3
3 Cited Publications
Cat. No.: HY-P2264
CAS No.: 676657-00-4
Target:  

Ephrin Receptor

Research Areas:  

Inflammation/Immunology

KYL peptide, an antagonistic peptide, selectively targets EphA4 receptor (IC50:4.22 μM, Kd:1.3 μM). KYL peptide binds to the ligand-binding domain of EphA4, effectively alleviates Aβ-induced synaptic dysfunction and synaptic plasticity defects in AD mice. KYL peptide can promote nerve regeneration after injury and modulating immune responses .
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3
3 Cited Publications
Cat. No.: HY-K0225

MCE Carboxyl Magnetic beads (200 nm, 10 mg/mL) are characterized by superparamagnetism, fast magnetic response, abundant carboxyl functional groups, monodispersity, and submicron scale particle size. Biological ligands (proteins, peptides, oligonucleotides, drug molecules, etc.) can be covalently coupled to the surface of microspheres under the action of special chemical reagents (such as EDC).

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2
2 Cited Publications
Cat. No.: HY-P3108
CAS No.: 1176306-10-7
Alamandine, a member of the renin-angiotensin system (RAS), a vasoactive peptide, is an endogenous ligand of the G protein-coupled receptor MrgD. Alamandine targets to protect the kidney and heart through anti-hypertensive actions .
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2
2 Cited Publications
Cat. No.: HY-P4803
CAS No.: 202933-49-1
PAR-2 (1-6) (human) (SLIGKV), a peptide ligand, is a PAR-2 agonist .
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2
2 Cited Publications
Cat. No.: HY-P72791
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL5; Chemokine (C-X-C Motif) ligand 5; Prev. SCYB5; Neutrophil-Activating Protein 78; ENA-78; Small-Inducible Cytokine B5; Small Inducible Cytokine Subfamily B (Cys-X-Cys), Member 5 (Epithelial-Derived Neutrophil-Activating peptide 78); C-X-C Motif Chem
Species:  
Mouse
Source:  
E. coli
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2
2 Cited Publications
Cat. No.: HY-P1014
CAS No.: 119911-68-1
Synonyms: Human α-CGRP (8-37)
Target:  

CGRP Receptor

Research Areas:  

Cardiovascular Disease

HCGRP-(8-37) (Human α-CGRP (8-37)) is a fragment of human calcitonin gene-related peptide (hCGRP) and an antagonist of the CGRP receptor, with an IC50 of 32.1 pM against the CGRP receptor. HCGRP-(8-37) blocks adenylate cyclase activation induced by CGRP receptor ligands and attenuates vascular responses triggered by CGRP. HCGRP-(8-37) reduces capsaicin-induced vasodilation in porcine nasal mucosa and superficial skin. HCGRP-(8-37) serves as a research tool to distinguish effects mediated by CGRP or calcitonin receptors, and to investigate CGRP-induced vascular effects .
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1
1 Cited Publications
Cat. No.: HY-P0272
CAS No.: 106362-32-7
Target:  

HIV

Research Areas:  

Infection

Peptide T is an octapeptide from the V2 region of HIV-1 gp120. Peptide T is a ligand for the CD4 receptor and prevents binding of HIV to the CD4 receptor.
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1
1 Cited Publications
Cat. No.: HY-P10086
CAS No.: 1289375-12-7
Synonyms: Human TREM-1(213-221)
TREM-1 inhibitory peptide GF9 (Human TREM-1 (213-221)) is a TREM-1 inhibitor. TREM-1 inhibitory peptide GF9 blocks the TREM-1 signaling pathway via a ligand-independent mechanism, spontaneously inserts into the cell membrane to dissociate TREM-1 from DAP-12, and functions through the Signaling Chain Homooligomerization (SCHOOL) model. TREM-1 inhibitory peptide GF9 reduces the levels of TNFα, IL-1β, IL-6, and M-CSF. TREM-1 inhibitory peptide GF9 inhibits tumor growth, prolongs the survival of mice with pancreatic cancer models, ameliorates collagen-induced arthritis, and exerts protective effects on bone and cartilage simultaneously. TREM-1 inhibitory peptide GF9 can be used in research related to arthritis, pancreatic cancer, retinopathy, alcoholic liver disease, and liver cancer .
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1
1 Cited Publications
Cat. No.: HY-P99263
CAS No.: 1256258-86-2
Synonyms: Anti-Human selectin P Recombinant Antibody

Target:  

P-selectin

Research Areas:  

Cardiovascular Disease

Inclacumab (Anti-Human selectin P Recombinant Antibody) is a human monoclonal IgG4 antibody selectively targets P-selectin with a Kd value of 9.9 nM. Inclacumab inhibits P-selectin glycoprotein ligand 1 (PSGL-1) mimetic peptide bind with P-selectin with an IC50 value of 1.9 μg/mL and strongly inhibits cell adhesion .
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1
1 Cited Publications
Cat. No.: HY-P7157
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL5; Chemokine (C-X-C Motif) ligand 5; Prev. SCYB5; Neutrophil-Activating Protein 78; ENA-78; Small-Inducible Cytokine B5; Small Inducible Cytokine Subfamily B (Cys-X-Cys), Member 5 (Epithelial-Derived Neutrophil-Activating peptide 78); C-X-C Motif Chem
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P7158
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL5; Chemokine (C-X-C Motif) ligand 5; Prev. SCYB5; Neutrophil-Activating Protein 78; ENA-78; Small-Inducible Cytokine B5; Small Inducible Cytokine Subfamily B (Cys-X-Cys), Member 5 (Epithelial-Derived Neutrophil-Activating peptide 78); C-X-C Motif Chem
Species:  
Human
Source:  
E. coli
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